| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0699296 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0671689 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0626265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0580297 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0579725 |
| RNF149 | ring finger protein 149 | 0.0512132 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.048453 |
| PTGR1 | prostaglandin reductase 1 | 0.0434084 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0418384 |
| TXNIP | thioredoxin interacting protein | 0.0403254 |
| RNF43 | ring finger protein 43 | 0.0388909 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0360063 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0351137 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0337616 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.032656 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0316235 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0312438 |
| UBAC2 | UBA domain containing 2 | 0.0308259 |
| MEIS2 | Meis homeobox 2 | 0.0304514 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0301935 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0298326 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0297407 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0292307 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0289775 |
| APOL1 | apolipoprotein L, 1 | 0.0277513 |
| EHBP1 | EH domain binding protein 1 | 0.0268634 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0267329 |
| ANXA4 | annexin A4 | 0.0258518 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0257065 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0248575 |
| ZNF638 | zinc finger protein 638 | 0.024586 |
| TMEM135 | transmembrane protein 135 | 0.0242123 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0239222 |
| ZNF148 | zinc finger protein 148 | 0.0227632 |
| PTEN | phosphatase and tensin homolog | 0.0226288 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0221567 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.022016 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0214304 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0208034 |
| MEF2A | myocyte enhancer factor 2A | 0.0203139 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0202675 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0200275 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0199784 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0198501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0196968 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0189875 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0186415 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.018327 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.018193 |
| DENND4C | DENN/MADD domain containing 4C | 0.0177202 |
| TMEM123 | transmembrane protein 123 | 0.0177089 |
| TPCN1 | two pore segment channel 1 | 0.0175866 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0174471 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0174192 |
| WDR26 | WD repeat domain 26 | 0.017404 |
| SYTL3 | synaptotagmin-like 3 | 0.0172076 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0170892 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0170766 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0169571 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0167525 |
| IL20RA | interleukin 20 receptor, alpha | 0.016747 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0167257 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0166847 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.0165856 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0165474 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0165337 |
| DNM2 | dynamin 2 | 0.0164228 |
| CD99 | CD99 molecule | 0.0164094 |
| KIF16B | kinesin family member 16B | 0.0163897 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0162399 |
| PGK1 | phosphoglycerate kinase 1 | 0.0159125 |
| CCDC146 | coiled-coil domain containing 146 | 0.0157667 |
| ZNF652 | zinc finger protein 652 | 0.0157583 |
| PDS5B | PDS5 cohesin associated factor B | 0.0157202 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0156065 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0155413 |
| PRSS23 | protease, serine, 23 | 0.0154322 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0153384 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.015293 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0152696 |
| YEATS2 | YEATS domain containing 2 | 0.0150963 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.0150847 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0150584 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0149585 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0148529 |
| CNOT11 | CCR4-NOT transcription complex, subunit 11 | 0.0147687 |
| ITM2B | integral membrane protein 2B | 0.0146427 |
| CSNK1D | casein kinase 1, delta | 0.0145669 |
| CCDC14 | coiled-coil domain containing 14 | 0.0145658 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.014369 |
| ATXN1 | ataxin 1 | 0.0142014 |
| GALK2 | galactokinase 2 | 0.0141478 |
| CORIN | corin, serine peptidase | 0.0138809 |
| HUNK | hormonally up-regulated Neu-associated kinase | 0.0137829 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0137792 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.013763 |
| PHKB | phosphorylase kinase, beta | 0.0137015 |
| CMIP | c-Maf inducing protein | 0.0136609 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.013633 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0136317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.260041 |
| ANXA2 | annexin A2 | -0.181437 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.154664 |
| EGR1 | early growth response 1 | -0.153578 |
| MYO1E | myosin IE | -0.133517 |
| MACC1 | metastasis associated in colon cancer 1 | -0.111457 |
| SQSTM1 | sequestosome 1 | -0.110879 |
| B2M | beta-2-microglobulin | -0.110753 |
| EZR | ezrin | -0.108666 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0924436 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.090045 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0899009 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0868981 |
| TJP1 | tight junction protein 1 | -0.0761829 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0749011 |
| VCL | vinculin | -0.0743939 |
| JUN | jun proto-oncogene | -0.0726644 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0714555 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0703548 |
| LCN2 | lipocalin 2 | -0.070324 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0686093 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0683206 |
| RIGI | RNA sensor RIG-I | -0.0678299 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0676579 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.066292 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0630769 |
| IRF1 | interferon regulatory factor 1 | -0.0615106 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0607811 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0592168 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0591214 |
| AREG | amphiregulin | -0.0575299 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0571932 |
| SP100 | SP100 nuclear antigen | -0.0571158 |
| RRBP1 | ribosome binding protein 1 | -0.0568642 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0560595 |
| PLSCR1 | phospholipid scramblase 1 | -0.055464 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0549407 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0538336 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.053444 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0532417 |
| RUNX1 | runt-related transcription factor 1 | -0.0520763 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.050386 |
| INTS6 | integrator complex subunit 6 | -0.0502824 |
| PERP | PERP, TP53 apoptosis effector | -0.0500093 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0497686 |
| HLA-B | major histocompatibility complex, class I, B | -0.0495615 |
| RNF213 | ring finger protein 213 | -0.0491399 |
| ATP11A | ATPase, class VI, type 11A | -0.0482275 |
| ACTN4 | actinin, alpha 4 | -0.0472061 |
| EFNB2 | ephrin-B2 | -0.0471482 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0469813 |
| ITGA6 | integrin, alpha 6 | -0.0468958 |
| CCNL1 | cyclin L1 | -0.0466053 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0465357 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0464636 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0461122 |
| VMP1 | vacuole membrane protein 1 | -0.0454428 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0453152 |
| MAP7 | microtubule-associated protein 7 | -0.0449029 |
| SPATA13 | spermatogenesis associated 13 | -0.0444219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0439411 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0436815 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0432133 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0429932 |
| SPAG9 | sperm associated antigen 9 | -0.0424354 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0418594 |
| SDC4 | syndecan 4 | -0.0415663 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0414831 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0413593 |
| GOLGB1 | golgin B1 | -0.0405759 |
| IRS2 | insulin receptor substrate 2 | -0.0393167 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0392838 |
| FTL | ferritin, light polypeptide | -0.0385963 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0383494 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0383225 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0379031 |
| KLF6 | Kruppel-like factor 6 | -0.0377782 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0377258 |
| ERBIN | erbb2 interacting protein | -0.0376872 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0374342 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0369009 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0366149 |
| TMC5 | transmembrane channel-like 5 | -0.0365355 |
| ACTG1 | actin gamma 1 | -0.0362764 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0362566 |
| MORF4L2 | mortality factor 4 like 2 | -0.0356409 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0344876 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0334307 |
| MX1 | MX dynamin-like GTPase 1 | -0.0332447 |
| S100A10 | S100 calcium binding protein A10 | -0.0331514 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0325761 |
| RPS6 | ribosomal protein S6 | -0.0325407 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0324643 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0319029 |
| DUSP10 | dual specificity phosphatase 10 | -0.0318637 |
| TOP1 | topoisomerase (DNA) I | -0.0318361 |
| HM13 | histocompatibility (minor) 13 | -0.0317845 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.031773 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0317194 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0312978 |
