| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.1877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.15342 |
| FAM13A | family with sequence similarity 13, member A | 0.103787 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0919688 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0909992 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0909358 |
| STC1 | stanniocalcin 1 | 0.0882161 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0825746 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0817747 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0773211 |
| HELZ | helicase with zinc finger | 0.0733882 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0732218 |
| RTN4 | reticulon 4 | 0.0624173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0603333 |
| CANX | calnexin | 0.0598425 |
| TXNIP | thioredoxin interacting protein | 0.0579441 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0572823 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0564416 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0549771 |
| ATP13A3 | ATPase type 13A3 | 0.0529562 |
| SMAD3 | SMAD family member 3 | 0.0509329 |
| ZNF395 | zinc finger protein 395 | 0.04983 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0495702 |
| OGA | O-GlcNAcase | 0.0488997 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0471337 |
| MAP1B | microtubule-associated protein 1B | 0.0459172 |
| GOLGA4 | golgin A4 | 0.0459155 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0455976 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0455907 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0451984 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.04401 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0436653 |
| SBF2 | SET binding factor 2 | 0.0417581 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0416208 |
| SNX13 | sorting nexin 13 | 0.0414547 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0413747 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0399439 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0393828 |
| USP3 | ubiquitin specific peptidase 3 | 0.0393029 |
| MT1X | metallothionein 1X | 0.0390728 |
| COG5 | component of oligomeric golgi complex 5 | 0.0384153 |
| SETD5 | SET domain containing 5 | 0.0380534 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0377424 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0376849 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0376078 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0371921 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0371449 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0363904 |
| COPA | coatomer protein complex, subunit alpha | 0.0362277 |
| CLTC | clathrin, heavy chain (Hc) | 0.0355225 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0354261 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0349964 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0349181 |
| RLF | rearranged L-myc fusion | 0.0349017 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0343151 |
| LRRC49 | leucine rich repeat containing 49 | 0.0342668 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0341748 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0338573 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0336132 |
| STK17A | serine/threonine kinase 17a | 0.0333532 |
| PHF21A | PHD finger protein 21A | 0.0332551 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0330469 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0329113 |
| TXNRD1 | thioredoxin reductase 1 | 0.0329023 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.032861 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0327982 |
| INSIG2 | insulin induced gene 2 | 0.0324713 |
| TFG | TRK-fused gene | 0.031255 |
| SEC24D | SEC24 family member D | 0.0312123 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0310776 |
| RBM39 | RNA binding motif protein 39 | 0.0309399 |
| STK17B | serine/threonine kinase 17b | 0.0304616 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0304123 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0301899 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0300636 |
| ZNF292 | zinc finger protein 292 | 0.0298113 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.029523 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0291597 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0291417 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0290831 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0290378 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0290282 |
| ANO6 | anoctamin 6 | 0.0289773 |
| NOP58 | NOP58 ribonucleoprotein | 0.0288826 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.028822 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0287545 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0284019 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0283171 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.028317 |
| SFXN1 | sideroflexin 1 | 0.0280957 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0279349 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0278273 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0278259 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0277473 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0277324 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0276763 |
| USP47 | ubiquitin specific peptidase 47 | 0.0276483 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0275972 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0274843 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0274079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.24479 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.200239 |
| FN1 | fibronectin 1 | -0.136688 |
| HLA-B | major histocompatibility complex, class I, B | -0.111965 |
| TMSB10 | thymosin beta 10 | -0.104868 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.102801 |
| B2M | beta-2-microglobulin | -0.0912107 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0789473 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0729139 |
| IGF2 | insulin-like growth factor 2 | -0.0676944 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.065985 |
| VIM | vimentin | -0.0623656 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0615271 |
| HLA-A | major histocompatibility complex, class I, A | -0.0597698 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0570026 |
| MT2A | metallothionein 2A | -0.056729 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0552142 |
| ACTG1 | actin gamma 1 | -0.0499164 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.048967 |
| POTEF | POTE ankyrin domain family, member F | -0.0468602 |
| RPL37A | ribosomal protein L37a | -0.0468505 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0464682 |
| RPS8 | ribosomal protein S8 | -0.0460302 |
| PRSS23 | protease, serine, 23 | -0.0455355 |
| ZNF804A | zinc finger protein 804A | -0.044191 |
| NAV1 | neuron navigator 1 | -0.0441556 |
| RPL35A | ribosomal protein L35a | -0.0437561 |
| NLGN1 | neuroligin 1 | -0.0435921 |
| VCL | vinculin | -0.0428466 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0427213 |
| CLMP | CXADR-like membrane protein | -0.0417064 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0405502 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0386257 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0381841 |
| RPL23 | ribosomal protein L23 | -0.037473 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0363954 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0356371 |
| COL5A1 | collagen, type V, alpha 1 | -0.0343766 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0337669 |
| RPL31 | ribosomal protein L31 | -0.0332896 |
| INTS6 | integrator complex subunit 6 | -0.0332457 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0332272 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.031862 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.031488 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0311286 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309572 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0309553 |
| RPS6 | ribosomal protein S6 | -0.0301858 |
| PDLIM5 | PDZ and LIM domain 5 | -0.029943 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.029767 |
| DGKI | diacylglycerol kinase, iota | -0.0294678 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0292716 |
| ENO1 | enolase 1, (alpha) | -0.0291312 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0289872 |
| RIGI | RNA sensor RIG-I | -0.0286881 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0275799 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0274451 |
| OXR1 | oxidation resistance 1 | -0.0274091 |
| RPL19 | ribosomal protein L19 | -0.0271052 |
| ASPH | aspartate beta-hydroxylase | -0.0269541 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0268073 |
| RPS13 | ribosomal protein S13 | -0.0251784 |
| CD44 | CD44 molecule (Indian blood group) | -0.0250708 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0249626 |
| RPS27 | ribosomal protein S27 | -0.0247876 |
| EGR1 | early growth response 1 | -0.0242951 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0241671 |
| RACK1 | receptor for activated C kinase 1 | -0.0241492 |
| C1S | complement component 1, s subcomponent | -0.0240162 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0239874 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0234688 |
| RPL9 | ribosomal protein L9 | -0.0234468 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0232098 |
| S100A9 | S100 calcium binding protein A9 | -0.0232007 |
| C3 | complement component 3 | -0.0229673 |
| RPS14 | ribosomal protein S14 | -0.022891 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0228821 |
| PTK2 | protein tyrosine kinase 2 | -0.0228138 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0227761 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0227492 |
| CCND1 | cyclin D1 | -0.0227439 |
| RPL12 | ribosomal protein L12 | -0.0226516 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.022613 |
| MRC2 | mannose receptor, C type 2 | -0.0226035 |
| CALD1 | caldesmon 1 | -0.0225895 |
| XYLT1 | xylosyltransferase I | -0.0222496 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0220208 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0217685 |
| FGF13 | fibroblast growth factor 13 | -0.0217001 |
| RPL34 | ribosomal protein L34 | -0.0216343 |
| HIP1 | huntingtin interacting protein 1 | -0.0214616 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0214071 |
| CUX1 | cut-like homeobox 1 | -0.0211958 |
| SPMIP6 | sperm microtubule inner protein 6 | -0.0209941 |
| SEPTIN9 | septin 9 | -0.0209695 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0208888 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0205901 |
| CALR | calreticulin | -0.0204047 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0203848 |
| LRRC23 | leucine rich repeat containing 23 | -0.0203129 |
