| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0898235 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0888574 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0746071 |
| PRELID2 | PRELI domain containing 2 | 0.0725146 |
| SVIL | supervillin | 0.0715927 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0667906 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0648944 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.062351 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0543133 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0491426 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.048725 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0467685 |
| SSH2 | slingshot protein phosphatase 2 | 0.0458329 |
| ASPH | aspartate beta-hydroxylase | 0.0449614 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0442455 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0435426 |
| SMAD3 | SMAD family member 3 | 0.0434592 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0428968 |
| ATXN1 | ataxin 1 | 0.0413773 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0408812 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.040393 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0379877 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0361174 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.035226 |
| TGFA | transforming growth factor, alpha | 0.0347548 |
| ITGB8 | integrin, beta 8 | 0.032878 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0327971 |
| MACROD2 | MACRO domain containing 2 | 0.0324752 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0317889 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0308815 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0307077 |
| SUMF1 | sulfatase modifying factor 1 | 0.0301257 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0300686 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0294421 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0282453 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0282263 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0276795 |
| FAM3C | family with sequence similarity 3, member C | 0.0273814 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0273349 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0266855 |
| R3HDM1 | R3H domain containing 1 | 0.0266762 |
| GDA | guanine deaminase | 0.0262622 |
| TXNRD1 | thioredoxin reductase 1 | 0.0256929 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0256851 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0256286 |
| ZNF638 | zinc finger protein 638 | 0.0256114 |
| MYO9A | myosin IXA | 0.0254443 |
| ZNF609 | zinc finger protein 609 | 0.0253237 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | 0.0246588 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0244395 |
| HMGA2 | high mobility group AT-hook 2 | 0.0244194 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0243302 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0241013 |
| FNIP1 | folliculin interacting protein 1 | 0.023798 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0229036 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0228652 |
| NF1 | neurofibromin 1 | 0.0228585 |
| SMYD3 | SET and MYND domain containing 3 | 0.0227033 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0226431 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0226413 |
| TMEM165 | transmembrane protein 165 | 0.0222142 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0221963 |
| PCNX4 | pecanex 4 | 0.0218637 |
| PCED1B | PC-esterase domain containing 1B | 0.0217893 |
| FHIT | fragile histidine triad | 0.0217207 |
| AEBP2 | AE binding protein 2 | 0.0217181 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0213577 |
| RAD51B | RAD51 paralog B | 0.0212237 |
| NBEAL1 | neurobeachin-like 1 | 0.0210891 |
| DIAPH3 | diaphanous-related formin 3 | 0.0209721 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0206594 |
| UTRN | utrophin | 0.020457 |
| BPTF | bromodomain PHD finger transcription factor | 0.0203031 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.020236 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | 0.0202329 |
| ZFHX3 | zinc finger homeobox 3 | 0.020158 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0200329 |
| NBEA | neurobeachin | 0.0197556 |
| KLC1 | kinesin light chain 1 | 0.0197429 |
| USP34 | ubiquitin specific peptidase 34 | 0.0197391 |
| VCL | vinculin | 0.0197183 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0196621 |
| EGFR | epidermal growth factor receptor | 0.0196305 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0195867 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0194263 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0191682 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.018984 |
| METTL15 | methyltransferase like 15 | 0.0188539 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0188113 |
| EHBP1 | EH domain binding protein 1 | 0.0187691 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0187518 |
| MMS22L | MMS22-like, DNA repair protein | 0.0186896 |
| RBL1 | retinoblastoma-like 1 | 0.018495 |
| AIG1 | androgen-induced 1 | 0.0184614 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0184569 |
| PCNX2 | pecanex 2 | 0.0184564 |
| SPIDR | scaffolding protein involved in DNA repair | 0.01843 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0184117 |
| NUP214 | nucleoporin 214kDa | 0.0182957 |
| TUT4 | terminal uridylyl transferase 4 | 0.018171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.190893 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169782 |
| POTEF | POTE ankyrin domain family, member F | -0.123858 |
| TMSB10 | thymosin beta 10 | -0.113949 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.103412 |
| ACTG1 | actin gamma 1 | -0.101879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.101403 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0962226 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0957862 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.093685 |
| ENO1 | enolase 1, (alpha) | -0.0888159 |
| LDHA | lactate dehydrogenase A | -0.0886322 |
| RPL12 | ribosomal protein L12 | -0.0841066 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0818393 |
| RPS6 | ribosomal protein S6 | -0.0808906 |
| B2M | beta-2-microglobulin | -0.0799647 |
| RPL23 | ribosomal protein L23 | -0.0755599 |
| RPLP0 | ribosomal protein, large, P0 | -0.0751611 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0669042 |
| RPS19 | ribosomal protein S19 | -0.0649984 |
| HMGA1 | high mobility group AT-hook 1 | -0.0607599 |
| ANXA2 | annexin A2 | -0.0596339 |
| TPI1 | triosephosphate isomerase 1 | -0.059628 |
| PTMA | prothymosin, alpha | -0.056963 |
| RPL35A | ribosomal protein L35a | -0.0560878 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.055914 |
| KRT7 | keratin 7, type II | -0.0556585 |
| MT2A | metallothionein 2A | -0.0531765 |
| SQSTM1 | sequestosome 1 | -0.0525056 |
| PCBP2 | poly(rC) binding protein 2 | -0.0520703 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0519182 |
| S100A10 | S100 calcium binding protein A10 | -0.0511226 |
| RACK1 | receptor for activated C kinase 1 | -0.0510642 |
| TPM4 | tropomyosin 4 | -0.0509035 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.050614 |
| RPLP1 | ribosomal protein, large, P1 | -0.0489001 |
| RPS12 | ribosomal protein S12 | -0.0484742 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0479596 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0465649 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0465244 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0465183 |
| RPS8 | ribosomal protein S8 | -0.0458767 |
| PKM | pyruvate kinase, muscle | -0.0454732 |
| RPS4X | ribosomal protein S4, X-linked | -0.0448924 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0444926 |
| RPL19 | ribosomal protein L19 | -0.0439749 |
| RPL32 | ribosomal protein L32 | -0.043708 |
| PGK1 | phosphoglycerate kinase 1 | -0.0434261 |
| RPL11 | ribosomal protein L11 | -0.0432457 |
| RPS14 | ribosomal protein S14 | -0.0420828 |
| RPL35 | ribosomal protein L35 | -0.0412164 |
| LAMB3 | laminin, beta 3 | -0.0411648 |
| NDRG1 | N-myc downstream regulated 1 | -0.0409429 |
| S100A9 | S100 calcium binding protein A9 | -0.0399838 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0387249 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.038427 |
| RPS11 | ribosomal protein S11 | -0.0377302 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0376394 |
| RPL15 | ribosomal protein L15 | -0.036435 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0355969 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0345215 |
| WWC1 | WW and C2 domain containing 1 | -0.034422 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0343553 |
| YBX1 | Y box binding protein 1 | -0.0341394 |
| UBC | ubiquitin C | -0.0341235 |
| DSPP | dentin sialophosphoprotein | -0.0340586 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0339922 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0339384 |
| TUBA1B | tubulin, alpha 1b | -0.0339363 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336684 |
| RPS5 | ribosomal protein S5 | -0.0336684 |
| S100A6 | S100 calcium binding protein A6 | -0.0335885 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0332806 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0332703 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0331064 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0329254 |
| EGR1 | early growth response 1 | -0.0329055 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0328457 |
| RPL31 | ribosomal protein L31 | -0.0327612 |
| IRS2 | insulin receptor substrate 2 | -0.0323354 |
| PAX8 | paired box 8 | -0.0323117 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0320674 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0316994 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0315364 |
| CALR | calreticulin | -0.0314287 |
| VCAN | versican | -0.0311365 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.030856 |
| SLMAP | sarcolemma associated protein | -0.030678 |
| RPL36 | ribosomal protein L36 | -0.0305397 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0303101 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0301196 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0300027 |
| EZR | ezrin | -0.0299353 |
| RPL8 | ribosomal protein L8 | -0.0298693 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.029693 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0296164 |
| CLDN4 | claudin 4 | -0.0295666 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0293071 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.029113 |
| PLAU | plasminogen activator, urokinase | -0.0289818 |
