| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbidopa (monohydrate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.191725 |
| FNDC3B | fibronectin type III domain containing 3B | 0.148982 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.109761 |
| SLC38A2 | solute carrier family 38, member 2 | 0.101881 |
| DTNA | dystrobrevin, alpha | 0.0798308 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0791359 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0667205 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0633197 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0589587 |
| FN1 | fibronectin 1 | 0.0579805 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0541873 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0529099 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0502779 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0501221 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0490339 |
| ZNF292 | zinc finger protein 292 | 0.0478272 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.046046 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0457461 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0442008 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0429013 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0419085 |
| INSIG2 | insulin induced gene 2 | 0.0405486 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0397145 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0392525 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0390643 |
| CPE | carboxypeptidase E | 0.0389785 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0385362 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0379837 |
| WDR45B | WD repeat domain 45B | 0.035813 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0357573 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0357444 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0349526 |
| PRELID2 | PRELI domain containing 2 | 0.0349243 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.034571 |
| RTN4 | reticulon 4 | 0.034474 |
| KIF1B | kinesin family member 1B | 0.0344528 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0342748 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.034246 |
| SEC24A | SEC24 family member A | 0.0342025 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0335981 |
| NGLY1 | N-glycanase 1 | 0.0329872 |
| STK17A | serine/threonine kinase 17a | 0.0329176 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0327167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0316231 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0311867 |
| KIAA1217 | KIAA1217 | 0.0307363 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.030735 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0304507 |
| PGK1 | phosphoglycerate kinase 1 | 0.0303643 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0302218 |
| AHSG | alpha-2-HS-glycoprotein | 0.0301942 |
| TNS1 | tensin 1 | 0.0294683 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0292322 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0292212 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0286286 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0285632 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0283681 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.0282027 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0281941 |
| PLIN2 | perilipin 2 | 0.0280028 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0279066 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0276019 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0273528 |
| A1CF | APOBEC1 complementation factor | 0.0269822 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0268596 |
| RNF145 | ring finger protein 145 | 0.0268166 |
| TF | transferrin | 0.0266977 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.026609 |
| HLF | hepatic leukemia factor | 0.0266003 |
| LYZ | lysozyme | 0.0263733 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0262998 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0259922 |
| HLA-A | major histocompatibility complex, class I, A | 0.0257183 |
| FGB | fibrinogen beta chain | 0.0252229 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0246771 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0246006 |
| APOA2 | apolipoprotein A-II | 0.0244176 |
| PTK2 | protein tyrosine kinase 2 | 0.0239376 |
| VEGFA | vascular endothelial growth factor A | 0.0236065 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0235947 |
| FAM13A | family with sequence similarity 13, member A | 0.0235553 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0234323 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0234288 |
| NBAS | neuroblastoma amplified sequence | 0.0233718 |
| LPIN2 | lipin 2 | 0.0231086 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0230677 |
| LRRC1 | leucine rich repeat containing 1 | 0.0230605 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0228316 |
| RBM25 | RNA binding motif protein 25 | 0.0228109 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0226928 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0225739 |
| ATP10A | ATPase, class V, type 10A | 0.0224446 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0224157 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.022324 |
| MYO1B | myosin IB | 0.0223002 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.0220056 |
| HELZ | helicase with zinc finger | 0.0219751 |
| CANX | calnexin | 0.0218955 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0216825 |
| KIF21A | kinesin family member 21A | 0.0214615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | -0.178571 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.162432 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.161817 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.142603 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.135152 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.132913 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11058 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.108909 |
| SVIL | supervillin | -0.0922352 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0856941 |
| APOB | apolipoprotein B | -0.0803976 |
| GPC3 | glypican 3 | -0.0717428 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0712354 |
| VCL | vinculin | -0.0693772 |
| CTSB | cathepsin B | -0.0671314 |
| BCL2L1 | BCL2-like 1 | -0.0632216 |
| FOXP1 | forkhead box P1 | -0.0623999 |
| SMAD3 | SMAD family member 3 | -0.0601757 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0584117 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0576847 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0567934 |
| MRTFA | myocardin related transcription factor A | -0.0557724 |
| RPS2 | ribosomal protein S2 | -0.0551035 |
| RPL11 | ribosomal protein L11 | -0.0535274 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0517341 |
| RRBP1 | ribosome binding protein 1 | -0.0494645 |
| LCN2 | lipocalin 2 | -0.0485616 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0471808 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0465256 |
| FAM107B | family with sequence similarity 107, member B | -0.0463765 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0449085 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0443214 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0436039 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0434262 |
| ITGAV | integrin, alpha V | -0.0418234 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0415786 |
| RBM39 | RNA binding motif protein 39 | -0.0414181 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.041297 |
| RPL38 | ribosomal protein L38 | -0.0410255 |
| IGF2 | insulin-like growth factor 2 | -0.0410204 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0409861 |
| CFB | complement factor B | -0.0399457 |
| JAK1 | Janus kinase 1 | -0.0391674 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0391349 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0389017 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0388766 |
| RPLP0 | ribosomal protein, large, P0 | -0.0388613 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0386887 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0384866 |
| MT2A | metallothionein 2A | -0.0379322 |
| FRMD5 | FERM domain containing 5 | -0.0371911 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0368118 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0362781 |
| FAT1 | FAT atypical cadherin 1 | -0.0362239 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.0357295 |
| RPS12 | ribosomal protein S12 | -0.0356307 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0354223 |
| ZFHX3 | zinc finger homeobox 3 | -0.0352508 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0350977 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0349442 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.034836 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0348248 |
| LMO7 | LIM domain 7 | -0.0346635 |
| SERINC1 | serine incorporator 1 | -0.034496 |
| RPS24 | ribosomal protein S24 | -0.0344284 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0342732 |
| VMP1 | vacuole membrane protein 1 | -0.034094 |
| SKI | SKI proto-oncogene | -0.0339028 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0337379 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0337279 |
| A2M | alpha-2-macroglobulin | -0.0336238 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0333817 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0331291 |
| RASA2 | RAS p21 protein activator 2 | -0.0328121 |
| TMSB10 | thymosin beta 10 | -0.0327844 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.032677 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0326438 |
| PTCHD4 | patched domain containing 4 | -0.032588 |
| HPCAL1 | hippocalcin-like 1 | -0.0321207 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0320829 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0320107 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.031934 |
| CLTC | clathrin, heavy chain (Hc) | -0.0318409 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0315538 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0315459 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0313763 |
| KYNU | kynureninase | -0.0311508 |
| UBC | ubiquitin C | -0.0304512 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0297616 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0297446 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0297024 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0296991 |
| RPL7 | ribosomal protein L7 | -0.0295502 |
| SMYD3 | SET and MYND domain containing 3 | -0.0294733 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0292967 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0287925 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0285792 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0281767 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0281489 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0280395 |
