| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbidopa (monohydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0901902 |
| RIN2 | Ras and Rab interactor 2 | 0.0786341 |
| NDRG1 | N-myc downstream regulated 1 | 0.0718636 |
| NRG1 | neuregulin 1 | 0.0678877 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0628318 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0616539 |
| MEF2A | myocyte enhancer factor 2A | 0.0613569 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0595537 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0512508 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0502721 |
| ITGA6 | integrin, alpha 6 | 0.050072 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0500235 |
| PRELID2 | PRELI domain containing 2 | 0.049984 |
| KIAA1217 | KIAA1217 | 0.0484964 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0447734 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0431227 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0398437 |
| DOK5 | docking protein 5 | 0.039513 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0379397 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0372976 |
| EHF | ets homologous factor | 0.0368952 |
| TNS4 | tensin 4 | 0.0368297 |
| PLAT | plasminogen activator, tissue | 0.0365796 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0360663 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0359435 |
| METTL15 | methyltransferase like 15 | 0.0355182 |
| FOXP1 | forkhead box P1 | 0.0353797 |
| ITGB4 | integrin, beta 4 | 0.0351504 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0350842 |
| ZNF292 | zinc finger protein 292 | 0.034347 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0340814 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0338969 |
| BCL2L1 | BCL2-like 1 | 0.0333882 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0331294 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0321939 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0318178 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0313625 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0310452 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0307127 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.030648 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0284082 |
| LAMA5 | laminin, alpha 5 | 0.0281031 |
| IFI44 | interferon-induced protein 44 | 0.0268619 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0260873 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0260762 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0259067 |
| KIAA0040 | KIAA0040 | 0.0254795 |
| OSMR | oncostatin M receptor | 0.0253063 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0252463 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0250452 |
| GATA6 | GATA binding protein 6 | 0.0249275 |
| MT1X | metallothionein 1X | 0.0249169 |
| FLOT1 | flotillin 1 | 0.0245439 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.024497 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0244436 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0244312 |
| ACER3 | alkaline ceramidase 3 | 0.0242701 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0241451 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0240825 |
| NEK7 | NIMA-related kinase 7 | 0.023823 |
| FLNB | filamin B, beta | 0.0234272 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0228179 |
| RNF220 | ring finger protein 220 | 0.0222486 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0222481 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.021885 |
| AOPEP | aminopeptidase O (putative) | 0.0218299 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0218143 |
| FOSL1 | FOS-like antigen 1 | 0.0216805 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0216079 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0213835 |
| ANLN | anillin, actin binding protein | 0.021122 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0210214 |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.0209251 |
| AUTS2 | autism susceptibility candidate 2 | 0.0207777 |
| DIAPH3 | diaphanous-related formin 3 | 0.0206828 |
| ASPH | aspartate beta-hydroxylase | 0.0206347 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0205894 |
| NF1 | neurofibromin 1 | 0.0204302 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0203072 |
| TXNIP | thioredoxin interacting protein | 0.0201871 |
| SSH1 | slingshot protein phosphatase 1 | 0.0201628 |
| CD99 | CD99 molecule | 0.0201036 |
| CFDP1 | craniofacial development protein 1 | 0.0200909 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0197293 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0196082 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0195129 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0194944 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0194894 |
| NFIA | nuclear factor I/A | 0.0193254 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0192596 |
| MYO9A | myosin IXA | 0.0190995 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0187752 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0187583 |
| IFI44L | interferon-induced protein 44-like | 0.0184623 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0184548 |
| PHKB | phosphorylase kinase, beta | 0.018385 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0182485 |
| CUL4B | cullin 4B | 0.0181741 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0180045 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.017938 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.130163 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.123851 |
| LMO7 | LIM domain 7 | -0.102339 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0917676 |
| LDHA | lactate dehydrogenase A | -0.0908897 |
| ENO1 | enolase 1, (alpha) | -0.0899575 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0874772 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0854345 |
| PTMA | prothymosin, alpha | -0.0846487 |
| ANXA1 | annexin A1 | -0.0784961 |
| SQSTM1 | sequestosome 1 | -0.072969 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0707674 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0703492 |
| KRT17 | keratin 17, type I | -0.0702389 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0616448 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0612221 |
| TMSB10 | thymosin beta 10 | -0.0607056 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0585106 |
| EXT1 | exostosin glycosyltransferase 1 | -0.054265 |
| SQLE | squalene epoxidase | -0.0523841 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0522164 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0521274 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0510434 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0499104 |
| RBM39 | RNA binding motif protein 39 | -0.0493271 |
| PLS3 | plastin 3 | -0.0487108 |
| MORF4L2 | mortality factor 4 like 2 | -0.048089 |
| CD44 | CD44 molecule (Indian blood group) | -0.0480265 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.047585 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0468541 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0464046 |
| B2M | beta-2-microglobulin | -0.0462843 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.046033 |
| INTS6 | integrator complex subunit 6 | -0.0457904 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0439867 |
| MTSS1 | metastasis suppressor 1 | -0.043217 |
| ANXA2 | annexin A2 | -0.0427757 |
| RASAL2 | RAS protein activator like 2 | -0.0422476 |
| HM13 | histocompatibility (minor) 13 | -0.0415404 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0413263 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0411438 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0409126 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0407079 |
| SULF1 | sulfatase 1 | -0.0406776 |
| TMSB4X | thymosin beta 4, X-linked | -0.0404803 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0401083 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0400053 |
| GOLGA4 | golgin A4 | -0.0395137 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.039076 |
| KRT6A | keratin 6A, type II | -0.0390534 |
| VCL | vinculin | -0.038847 |
| CANX | calnexin | -0.0385042 |
| STC1 | stanniocalcin 1 | -0.0380764 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0380686 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0372583 |
| RAI14 | retinoic acid induced 14 | -0.0368294 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0367898 |
| POTEF | POTE ankyrin domain family, member F | -0.0365896 |
| ANKRD11 | ankyrin repeat domain 11 | -0.036397 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0360097 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0358486 |
| LAMC2 | laminin, gamma 2 | -0.0351843 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0351711 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0350502 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.034922 |
| CALU | calumenin | -0.0349042 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0344369 |
| RPS8 | ribosomal protein S8 | -0.0339249 |
| DSTN | destrin (actin depolymerizing factor) | -0.0338931 |
| NAV2 | neuron navigator 2 | -0.0336947 |
| RND3 | Rho family GTPase 3 | -0.0335111 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0333056 |
| RPS6 | ribosomal protein S6 | -0.0329821 |
| EZR | ezrin | -0.0322483 |
| FAM107B | family with sequence similarity 107, member B | -0.0321832 |
| SPAG9 | sperm associated antigen 9 | -0.032183 |
| KRT14 | keratin 14, type I | -0.0319505 |
| RPL11 | ribosomal protein L11 | -0.0316609 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0313262 |
| IGF2 | insulin-like growth factor 2 | -0.0312064 |
| FTL | ferritin, light polypeptide | -0.0309978 |
| GOLGB1 | golgin B1 | -0.030355 |
| RPL37 | ribosomal protein L37 | -0.0301762 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0298069 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0297569 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0297039 |
| ATF4 | activating transcription factor 4 | -0.0296694 |
| RPLP0 | ribosomal protein, large, P0 | -0.0296304 |
| RACK1 | receptor for activated C kinase 1 | -0.0295013 |
| JMJD1C | jumonji domain containing 1C | -0.029194 |
| SULF2 | sulfatase 2 | -0.0290297 |
| FN1 | fibronectin 1 | -0.0288532 |
| RPL12 | ribosomal protein L12 | -0.0288086 |
| HLA-E | major histocompatibility complex, class I, E | -0.028805 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0286688 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0286595 |
| HDLBP | high density lipoprotein binding protein | -0.028407 |
| QKI | QKI, KH domain containing, RNA binding | -0.0281374 |
| RCOR1 | REST corepressor 1 | -0.0278714 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0278655 |
