| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.226477 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.126297 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.109584 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.10902 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.108416 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.102939 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.102396 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0903601 |
| ATP13A3 | ATPase type 13A3 | 0.0800065 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0792553 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0782632 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.077514 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0716673 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0660937 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0641395 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0590849 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0567714 |
| NDRG1 | N-myc downstream regulated 1 | 0.0540052 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0508963 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.050036 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0476152 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0469522 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0462981 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0458627 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0454825 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0433978 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.042457 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0414191 |
| FLNB | filamin B, beta | 0.040842 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0407676 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0386612 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0370377 |
| PDE10A | phosphodiesterase 10A | 0.0368379 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0366003 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0345152 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0342324 |
| RAI14 | retinoic acid induced 14 | 0.0332924 |
| MMP12 | matrix metallopeptidase 12 | 0.0330277 |
| TMEM165 | transmembrane protein 165 | 0.0317866 |
| PODXL | podocalyxin-like | 0.0317122 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0312684 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0309253 |
| TMEM41B | transmembrane protein 41B | 0.0308761 |
| RNF144B | ring finger protein 144B | 0.0295288 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0293038 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.029212 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.0282214 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0271128 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0270172 |
| CARD16 | caspase recruitment domain family, member 16 | 0.026494 |
| TRAM2 | translocation associated membrane protein 2 | 0.0263354 |
| ERBIN | erbb2 interacting protein | 0.026209 |
| NUP58 | nucleoporin 58 | 0.0260607 |
| VEGFC | vascular endothelial growth factor C | 0.0260038 |
| TPD52 | tumor protein D52 | 0.0259846 |
| SETD5 | SET domain containing 5 | 0.0258484 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0251349 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0251068 |
| FN1 | fibronectin 1 | 0.024805 |
| ANXA2 | annexin A2 | 0.0246354 |
| KLF9 | Kruppel-like factor 9 | 0.0240194 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.023587 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.0229516 |
| AFAP1 | actin filament associated protein 1 | 0.0228965 |
| DENND4C | DENN/MADD domain containing 4C | 0.0228513 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0227559 |
| FOSL1 | FOS-like antigen 1 | 0.0223589 |
| NUP153 | nucleoporin 153kDa | 0.0222579 |
| GLIS3 | GLIS family zinc finger 3 | 0.0211612 |
| OSMR | oncostatin M receptor | 0.0209338 |
| GRAMD2B | GRAM domain containing 2B | 0.0209163 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0207298 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0205789 |
| YEATS2 | YEATS domain containing 2 | 0.0205624 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0205534 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.020541 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0203722 |
| NGLY1 | N-glycanase 1 | 0.0203374 |
| SPAG9 | sperm associated antigen 9 | 0.0200159 |
| TGFB2 | transforming growth factor, beta 2 | 0.0199138 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0197478 |
| XPO1 | exportin 1 | 0.0195277 |
| CUL4B | cullin 4B | 0.0194929 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0194586 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0194286 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.019172 |
| LOX | lysyl oxidase | 0.0189533 |
| USP3 | ubiquitin specific peptidase 3 | 0.0188712 |
| PLIN2 | perilipin 2 | 0.0188697 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0188587 |
| VEGFA | vascular endothelial growth factor A | 0.018779 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0187098 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0186675 |
| SEC24A | SEC24 family member A | 0.0186537 |
| CCNL1 | cyclin L1 | 0.0186399 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0184324 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0181961 |
| ZNF292 | zinc finger protein 292 | 0.0180729 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0180688 |
| WDR45B | WD repeat domain 45B | 0.0178394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.256754 |
| MT2A | metallothionein 2A | -0.194838 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123651 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.10475 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0950035 |
| ENO1 | enolase 1, (alpha) | -0.0929475 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0812466 |
| TMSB10 | thymosin beta 10 | -0.0800223 |
| POTEF | POTE ankyrin domain family, member F | -0.0778482 |
| B2M | beta-2-microglobulin | -0.0767574 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0753282 |
| HLA-B | major histocompatibility complex, class I, B | -0.0750192 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.07388 |
| TLE4 | transducin-like enhancer of split 4 | -0.0698912 |
| ASPH | aspartate beta-hydroxylase | -0.0696588 |
| INTS6 | integrator complex subunit 6 | -0.068919 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0656849 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0597111 |
| RPS6 | ribosomal protein S6 | -0.0591468 |
| FLNA | filamin A, alpha | -0.0582902 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0578199 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0556876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.055264 |
| CALR | calreticulin | -0.0526338 |
| RPL23 | ribosomal protein L23 | -0.052111 |
| AHNAK | AHNAK nucleoprotein | -0.0500842 |
| UBC | ubiquitin C | -0.0491577 |
| RPLP2 | ribosomal protein, large, P2 | -0.0487464 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0482906 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0470488 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0461532 |
| RPL35A | ribosomal protein L35a | -0.0460972 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0454396 |
| RPL37 | ribosomal protein L37 | -0.0437635 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0427387 |
| SQSTM1 | sequestosome 1 | -0.0426431 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0407724 |
| SET | SET nuclear proto-oncogene | -0.0403682 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0400501 |
| RPS8 | ribosomal protein S8 | -0.0396659 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0394487 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0389905 |
| LDHA | lactate dehydrogenase A | -0.03858 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0381526 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0376156 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0370776 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.037006 |
| RPS19 | ribosomal protein S19 | -0.0365269 |
| PCBP2 | poly(rC) binding protein 2 | -0.0357667 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0356992 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0356613 |
| ACTG1 | actin gamma 1 | -0.0353463 |
| HMGB1 | high mobility group box 1 | -0.0352454 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0352141 |
| HMGB2 | high mobility group box 2 | -0.0347501 |
| RPLP1 | ribosomal protein, large, P1 | -0.0345758 |
| RPL11 | ribosomal protein L11 | -0.0344511 |
| PRELID2 | PRELI domain containing 2 | -0.0341109 |
| RPL12 | ribosomal protein L12 | -0.0333083 |
| MCL1 | myeloid cell leukemia 1 | -0.0329755 |
| GOLGB1 | golgin B1 | -0.0327343 |
| RAD51B | RAD51 paralog B | -0.0325663 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0324833 |
| PTMA | prothymosin, alpha | -0.0324231 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.032325 |
| DEK | DEK proto-oncogene | -0.0320576 |
| CENPF | centromere protein F, 350/400kDa | -0.0315637 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.031458 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.031432 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0311562 |
| RPS3 | ribosomal protein S3 | -0.0310846 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.03102 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0300544 |
| FUS | FUS RNA binding protein | -0.0299542 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0299202 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0298518 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0296244 |
| BRD2 | bromodomain containing 2 | -0.0295406 |
| RPL35 | ribosomal protein L35 | -0.0294655 |
| TUBB4B | tubulin, beta 4B class IVb | -0.029456 |
| RACK1 | receptor for activated C kinase 1 | -0.0291976 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0290468 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0281366 |
| PRRC2B | proline-rich coiled-coil 2B | -0.027631 |
| RPS27A | ribosomal protein S27a | -0.0274561 |
| CLIC4 | chloride intracellular channel 4 | -0.0274061 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.027281 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0269988 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0269286 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0267556 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0265385 |
| ACTN1 | actinin, alpha 1 | -0.0265035 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0264972 |
| RPL31 | ribosomal protein L31 | -0.0263789 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0262699 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0260724 |
| RPS13 | ribosomal protein S13 | -0.0259772 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0258777 |
| ATXN1 | ataxin 1 | -0.0258628 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0257703 |
