| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | 0.132062 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.111334 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.104503 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102199 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0934138 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0817845 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0815895 |
| EHBP1 | EH domain binding protein 1 | 0.0787525 |
| TMC5 | transmembrane channel-like 5 | 0.074839 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0639167 |
| BCL2L1 | BCL2-like 1 | 0.0633279 |
| ITGA6 | integrin, alpha 6 | 0.063101 |
| VEGFA | vascular endothelial growth factor A | 0.0614671 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0588472 |
| RNF213 | ring finger protein 213 | 0.0537849 |
| YAP1 | Yes-associated protein 1 | 0.0536147 |
| ATXN1 | ataxin 1 | 0.0481342 |
| CD46 | CD46 molecule, complement regulatory protein | 0.04754 |
| PKM | pyruvate kinase, muscle | 0.0473032 |
| AHR | aryl hydrocarbon receptor | 0.0441609 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0441143 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.043358 |
| MAGT1 | magnesium transporter 1 | 0.0426142 |
| CLDN7 | claudin 7 | 0.0425721 |
| AGR2 | anterior gradient 2 | 0.0422202 |
| CCNL1 | cyclin L1 | 0.0417418 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0414754 |
| TNS4 | tensin 4 | 0.0410255 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0405974 |
| NDRG1 | N-myc downstream regulated 1 | 0.0392768 |
| ITGB4 | integrin, beta 4 | 0.039052 |
| MCU | mitochondrial calcium uniporter | 0.0382358 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0376063 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0375617 |
| SHROOM3 | shroom family member 3 | 0.037504 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0366939 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0363078 |
| ASPH | aspartate beta-hydroxylase | 0.0360915 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0357877 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0357167 |
| TNIK | TRAF2 and NCK interacting kinase | 0.035267 |
| ACTN4 | actinin, alpha 4 | 0.0346327 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0345778 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0344347 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0341924 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0341778 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0338043 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0337754 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0328916 |
| PTEN | phosphatase and tensin homolog | 0.0328104 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0328042 |
| BPTF | bromodomain PHD finger transcription factor | 0.0327051 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0322428 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0318103 |
| NF1 | neurofibromin 1 | 0.0317046 |
| ATP11A | ATPase, class VI, type 11A | 0.0309782 |
| MECOM | MDS1 and EVI1 complex locus | 0.0309599 |
| TMEM123 | transmembrane protein 123 | 0.0308885 |
| NPSR1 | neuropeptide S receptor 1 | 0.030879 |
| MUC17 | mucin 17, cell surface associated | 0.0305939 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0302764 |
| WWC1 | WW and C2 domain containing 1 | 0.0302386 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0299031 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.029868 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0294586 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0292819 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.029188 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0287658 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0286438 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0284614 |
| RNF43 | ring finger protein 43 | 0.0284497 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0281474 |
| TRAM1 | translocation associated membrane protein 1 | 0.0279903 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0276942 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0276364 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0276254 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0274178 |
| NFIB | nuclear factor I/B | 0.0273485 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.027209 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0270934 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0270615 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0267486 |
| FAM135A | family with sequence similarity 135, member A | 0.0264702 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0260356 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.0259127 |
| ZNF292 | zinc finger protein 292 | 0.0253861 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0253372 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0252825 |
| LIMA1 | LIM domain and actin binding 1 | 0.0251589 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0251436 |
| AOPEP | aminopeptidase O (putative) | 0.0251257 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.025036 |
| ZNF652 | zinc finger protein 652 | 0.0250181 |
| SEPTIN9 | septin 9 | 0.0246076 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0245259 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0245165 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0244871 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0244859 |
| ATM | ATM serine/threonine kinase | 0.0244247 |
| ZNF148 | zinc finger protein 148 | 0.0243748 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140799 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.102645 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0984363 |
| TMSB10 | thymosin beta 10 | -0.0864823 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0843173 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0834227 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0722871 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0719332 |
| RPL35A | ribosomal protein L35a | -0.0710628 |
| RPL23 | ribosomal protein L23 | -0.0606782 |
| FTL | ferritin, light polypeptide | -0.0600829 |
| EMP1 | epithelial membrane protein 1 | -0.0536133 |
| RPL12 | ribosomal protein L12 | -0.0529733 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0503891 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0501899 |
| RPLP1 | ribosomal protein, large, P1 | -0.048783 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0457847 |
| KRT18 | keratin 18, type I | -0.0452743 |
| PTMA | prothymosin, alpha | -0.0436701 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0436473 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0431495 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0429248 |
| HMGB2 | high mobility group box 2 | -0.0398115 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0393935 |
| RPS3 | ribosomal protein S3 | -0.0371105 |
| RPS27A | ribosomal protein S27a | -0.0370065 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0366136 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0362356 |
| CALR | calreticulin | -0.0361901 |
| ANXA1 | annexin A1 | -0.0359782 |
| EPCAM | epithelial cell adhesion molecule | -0.0354759 |
| AHNAK | AHNAK nucleoprotein | -0.0351427 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0347562 |
| TES | testin LIM domain protein | -0.0343584 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0343067 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.033507 |
| SQSTM1 | sequestosome 1 | -0.0332893 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0328852 |
| RPL34 | ribosomal protein L34 | -0.0323414 |
| RPS19 | ribosomal protein S19 | -0.0320267 |
| RPL18 | ribosomal protein L18 | -0.0306948 |
| RPL26 | ribosomal protein L26 | -0.030609 |
| RPL11 | ribosomal protein L11 | -0.0304821 |
| CCDC47 | coiled-coil domain containing 47 | -0.0303591 |
| EZR | ezrin | -0.0300195 |
| HLA-C | major histocompatibility complex, class I, C | -0.0299943 |
| RPL19 | ribosomal protein L19 | -0.029748 |
| CALU | calumenin | -0.0295675 |
| HDLBP | high density lipoprotein binding protein | -0.0291712 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0286955 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.0284493 |
| SERINC1 | serine incorporator 1 | -0.0284095 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0282657 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0280673 |
| SRPRA | SRP receptor subunit alpha | -0.028 |
| RPS25 | ribosomal protein S25 | -0.0277586 |
| ACTG1 | actin gamma 1 | -0.0274776 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0273933 |
| CANX | calnexin | -0.0270737 |
| RPL13A | ribosomal protein L13a | -0.0269608 |
| RPL36A | ribosomal protein L36a | -0.0266466 |
| RPLP0 | ribosomal protein, large, P0 | -0.0265486 |
| DSPP | dentin sialophosphoprotein | -0.0264427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0262225 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0259777 |
| GSTP1 | glutathione S-transferase pi 1 | -0.025623 |
| RPS12 | ribosomal protein S12 | -0.0253609 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0249687 |
| RPL35 | ribosomal protein L35 | -0.0248267 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0244421 |
| RPL31 | ribosomal protein L31 | -0.024183 |
| RPLP2 | ribosomal protein, large, P2 | -0.0241448 |
| LAMB3 | laminin, beta 3 | -0.02378 |
| KRT7 | keratin 7, type II | -0.0237253 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0235629 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0232942 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0230207 |
| SPAG9 | sperm associated antigen 9 | -0.022513 |
| RPS4X | ribosomal protein S4, X-linked | -0.0225066 |
| RPS24 | ribosomal protein S24 | -0.0225009 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0224152 |
| VIM | vimentin | -0.0220863 |
| RPS27 | ribosomal protein S27 | -0.0217508 |
| CD9 | CD9 molecule | -0.0217267 |
| ENO1 | enolase 1, (alpha) | -0.0217254 |
| RPL27 | ribosomal protein L27 | -0.0217244 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0216586 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.02141 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0213169 |
| RPL32 | ribosomal protein L32 | -0.0212818 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0210595 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0210391 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0210315 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0209546 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0209177 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0207598 |
| UBB | ubiquitin B | -0.020698 |
| HLA-E | major histocompatibility complex, class I, E | -0.0203839 |
| RPS16 | ribosomal protein S16 | -0.0202439 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.0201013 |
