| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.288277 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.229546 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.125535 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0815791 |
| ACTG1 | actin gamma 1 | 0.073103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0710413 |
| NDRG1 | N-myc downstream regulated 1 | 0.0653073 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0592263 |
| EFNA5 | ephrin-A5 | 0.0579787 |
| MMP12 | matrix metallopeptidase 12 | 0.05328 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0528134 |
| PTMA | prothymosin, alpha | 0.0510382 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.049395 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0448789 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0446482 |
| RPS6 | ribosomal protein S6 | 0.0441425 |
| NF1 | neurofibromin 1 | 0.043125 |
| RPL23 | ribosomal protein L23 | 0.0422037 |
| CD109 | CD109 molecule | 0.0421763 |
| TXNIP | thioredoxin interacting protein | 0.0409554 |
| TMSB10 | thymosin beta 10 | 0.0405876 |
| GPC6 | glypican 6 | 0.0405496 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.039552 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0392658 |
| RPS20 | ribosomal protein S20 | 0.0360654 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0359166 |
| RPS19 | ribosomal protein S19 | 0.0355852 |
| RPL35A | ribosomal protein L35a | 0.0342651 |
| RPS25 | ribosomal protein S25 | 0.033785 |
| RPL37A | ribosomal protein L37a | 0.033422 |
| PHIP | pleckstrin homology domain interacting protein | 0.0330217 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0330055 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0312013 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.030645 |
| RPLP2 | ribosomal protein, large, P2 | 0.0303914 |
| MT2A | metallothionein 2A | 0.0302155 |
| FTL | ferritin, light polypeptide | 0.0292157 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0290441 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0288665 |
| RPS27A | ribosomal protein S27a | 0.028748 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0279624 |
| RPS3 | ribosomal protein S3 | 0.0279431 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.027679 |
| RPS23 | ribosomal protein S23 | 0.0276764 |
| RPLP1 | ribosomal protein, large, P1 | 0.0274222 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0273651 |
| PKM | pyruvate kinase, muscle | 0.0271643 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0271518 |
| NLGN1 | neuroligin 1 | 0.0267682 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0267364 |
| WDR45B | WD repeat domain 45B | 0.0265254 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0265134 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0263607 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0260777 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0259591 |
| ANO6 | anoctamin 6 | 0.025794 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0257243 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0256258 |
| SETD5 | SET domain containing 5 | 0.0254726 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0253166 |
| MYOF | myoferlin | 0.0253075 |
| CENPF | centromere protein F, 350/400kDa | 0.0249729 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0249689 |
| RPS13 | ribosomal protein S13 | 0.0248901 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0248459 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.024584 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.024367 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.024286 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0242777 |
| RPL19 | ribosomal protein L19 | 0.0241098 |
| ATXN1 | ataxin 1 | 0.024095 |
| SBF2 | SET binding factor 2 | 0.0238669 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0238005 |
| ZNF638 | zinc finger protein 638 | 0.0232296 |
| RPL7A | ribosomal protein L7a | 0.0227997 |
| RPL5 | ribosomal protein L5 | 0.0226339 |
| ZNF207 | zinc finger protein 207 | 0.0225988 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0225339 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0223594 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0219636 |
| RPL36A | ribosomal protein L36a | 0.02193 |
| CDK19 | cyclin-dependent kinase 19 | 0.0216864 |
| CDC27 | cell division cycle 27 | 0.0215249 |
| ATXN2 | ataxin 2 | 0.0213674 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.021342 |
| NGLY1 | N-glycanase 1 | 0.0213194 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0212272 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0209504 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0209147 |
| LDHA | lactate dehydrogenase A | 0.0209065 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0208346 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0205598 |
| USP34 | ubiquitin specific peptidase 34 | 0.0202828 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0202071 |
| CCNI | cyclin I | 0.0201321 |
| NBEAL1 | neurobeachin-like 1 | 0.0201163 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0200562 |
| STC1 | stanniocalcin 1 | 0.0200221 |
| RPS17 | ribosomal protein S17 | 0.0200081 |
| RPLP0 | ribosomal protein, large, P0 | 0.0199101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0672209 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0663006 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0584081 |
| ASPH | aspartate beta-hydroxylase | -0.0576025 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0548841 |
| JMJD1C | jumonji domain containing 1C | -0.0509942 |
| RTN4 | reticulon 4 | -0.0509779 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0509312 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0495766 |
| FRMD6 | FERM domain containing 6 | -0.0441327 |
| NABP1 | nucleic acid binding protein 1 | -0.0436522 |
| KYNU | kynureninase | -0.0408979 |
| WDR43 | WD repeat domain 43 | -0.0383503 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.037441 |
| HMGA2 | high mobility group AT-hook 2 | -0.0373879 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0354201 |
| NTM | neurotrimin | -0.0343998 |
| CALD1 | caldesmon 1 | -0.03204 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0317244 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0309167 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0302105 |
| CDK6 | cyclin-dependent kinase 6 | -0.0301903 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0298459 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0296628 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0296255 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0294478 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.029168 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0289953 |
| RPS2 | ribosomal protein S2 | -0.0287329 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0282057 |
| RPL4 | ribosomal protein L4 | -0.0280185 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0275704 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0273401 |
| KIAA1217 | KIAA1217 | -0.0271921 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0271083 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0266714 |
| HDAC9 | histone deacetylase 9 | -0.0265587 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0265395 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0263504 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0262173 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0254989 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0252082 |
| CD163L1 | CD163 molecule-like 1 | -0.0250621 |
| ANTXR2 | anthrax toxin receptor 2 | -0.024842 |
| RASA2 | RAS p21 protein activator 2 | -0.024657 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0246081 |
| CUL3 | cullin 3 | -0.0244812 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0244761 |
| RPL6 | ribosomal protein L6 | -0.0243641 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0240345 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0239562 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0235991 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0232953 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0232406 |
| CORO1C | coronin, actin binding protein, 1C | -0.0232144 |
| CD44 | CD44 molecule (Indian blood group) | -0.023057 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0229729 |
| EGR1 | early growth response 1 | -0.0224781 |
| TEX10 | testis expressed 10 | -0.0221719 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0218153 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0215165 |
| QKI | QKI, KH domain containing, RNA binding | -0.0214813 |
| CRY1 | cryptochrome circadian clock 1 | -0.0213352 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0212342 |
| TXNRD1 | thioredoxin reductase 1 | -0.0210113 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0208602 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0204427 |
| TNNC1 | troponin C type 1 (slow) | -0.0204188 |
| TPM3 | tropomyosin 3 | -0.0201411 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.02008 |
| ZNF804A | zinc finger protein 804A | -0.0199842 |
| YBX1 | Y box binding protein 1 | -0.0198958 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0198882 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0197879 |
| CDK17 | cyclin-dependent kinase 17 | -0.0196195 |
| PLS3 | plastin 3 | -0.0195866 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0195175 |
| H1-4 | H1.4 linker histone, cluster member | -0.0194952 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0191853 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0191657 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0189828 |
| MYO10 | myosin X | -0.0188686 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0186936 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0181975 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0181412 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0180379 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0179736 |
| CCNL1 | cyclin L1 | -0.0179179 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0179112 |
| IL6ST | interleukin 6 signal transducer | -0.0178496 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0175889 |
| MSN | moesin | -0.0175612 |
| FN1 | fibronectin 1 | -0.0173869 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0172933 |
| NAV3 | neuron navigator 3 | -0.0171703 |
| YBX3 | Y box binding protein 3 | -0.0171332 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0168625 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0168544 |
| MCL1 | myeloid cell leukemia 1 | -0.0168401 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0167762 |
