| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbidopa (monohydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.156911 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.149488 |
| TNS4 | tensin 4 | 0.140142 |
| RNF43 | ring finger protein 43 | 0.128874 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.112121 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.109439 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.107974 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0992499 |
| MED13L | mediator complex subunit 13-like | 0.0861451 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.081257 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0787184 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0781755 |
| EREG | epiregulin | 0.0700483 |
| INSIG1 | insulin induced gene 1 | 0.0675605 |
| FAM13A | family with sequence similarity 13, member A | 0.0638553 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0637882 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0616172 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0591637 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0581573 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.057659 |
| NDRG1 | N-myc downstream regulated 1 | 0.0573037 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0549748 |
| NFIA | nuclear factor I/A | 0.0532161 |
| EHF | ets homologous factor | 0.0532054 |
| PRELID2 | PRELI domain containing 2 | 0.0527139 |
| GOLGA4 | golgin A4 | 0.052549 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0520028 |
| CADPS | Ca++-dependent secretion activator | 0.0478412 |
| PKP2 | plakophilin 2 | 0.0476259 |
| GPHN | gephyrin | 0.0468584 |
| PTEN | phosphatase and tensin homolog | 0.0463525 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0463228 |
| OGA | O-GlcNAcase | 0.0449231 |
| CAB39 | calcium binding protein 39 | 0.0446509 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0442331 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0441572 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0440019 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0434416 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0431121 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0429336 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0427448 |
| TMEM135 | transmembrane protein 135 | 0.0416373 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0406487 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0404675 |
| SETD5 | SET domain containing 5 | 0.0392983 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0381976 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0378873 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0376594 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0370577 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0348339 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0346742 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0345239 |
| SNRK | SNF related kinase | 0.0342898 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0342123 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0340649 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0340438 |
| ZNF292 | zinc finger protein 292 | 0.0336768 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0330968 |
| ATXN1 | ataxin 1 | 0.0329938 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0327713 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0320752 |
| PRSS3 | protease, serine, 3 | 0.0320747 |
| METTL15 | methyltransferase like 15 | 0.0319224 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0317356 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.031484 |
| USP34 | ubiquitin specific peptidase 34 | 0.0314016 |
| EPCAM | epithelial cell adhesion molecule | 0.0312595 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0311306 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0310257 |
| GDF15 | growth differentiation factor 15 | 0.0309295 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0308662 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0308355 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.030678 |
| PLAC8 | placenta-specific 8 | 0.0306182 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0303164 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0302557 |
| VMP1 | vacuole membrane protein 1 | 0.0300411 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.029837 |
| PKM | pyruvate kinase, muscle | 0.0297757 |
| ETNK1 | ethanolamine kinase 1 | 0.0297063 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0296947 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0295477 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0294703 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0293934 |
| RNF145 | ring finger protein 145 | 0.0291406 |
| NF1 | neurofibromin 1 | 0.0291293 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0291291 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.029081 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0290803 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.028852 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.028681 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0286664 |
| TXNIP | thioredoxin interacting protein | 0.0284268 |
| CLDN7 | claudin 7 | 0.0281913 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0279885 |
| CDCP1 | CUB domain containing protein 1 | 0.0279594 |
| H1-0 | H1.0 linker histone | 0.0276543 |
| EXOC1 | exocyst complex component 1 | 0.0274853 |
| USP3 | ubiquitin specific peptidase 3 | 0.0271225 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0270292 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.139342 |
| TMSB10 | thymosin beta 10 | -0.13619 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.113684 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106736 |
| LMO7 | LIM domain 7 | -0.0951885 |
| MYO1E | myosin IE | -0.0917746 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0917075 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0888594 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0825958 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0743378 |
| LAMA4 | laminin, alpha 4 | -0.0648734 |
| ACTG1 | actin gamma 1 | -0.0628066 |
| EZR | ezrin | -0.0612493 |
| RPS6 | ribosomal protein S6 | -0.0568533 |
| MUC17 | mucin 17, cell surface associated | -0.055146 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0524316 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0490901 |
| TPM4 | tropomyosin 4 | -0.0474305 |
| RNF217 | ring finger protein 217 | -0.0447046 |
| FTL | ferritin, light polypeptide | -0.0442393 |
| MT2A | metallothionein 2A | -0.0438277 |
| RPS8 | ribosomal protein S8 | -0.0432837 |
| EGFR | epidermal growth factor receptor | -0.0430474 |
| KRT18 | keratin 18, type I | -0.0423074 |
| TFF1 | trefoil factor 1 | -0.0413271 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0403308 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0401973 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0400098 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0390909 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0390071 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0376907 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0373038 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0368064 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0364195 |
| POTEF | POTE ankyrin domain family, member F | -0.0360088 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0347252 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0343499 |
| ITGA6 | integrin, alpha 6 | -0.0340055 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.033957 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0332653 |
| FBXO11 | F-box protein 11 | -0.0331393 |
| LMNA | lamin A/C | -0.0330245 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0325602 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0316833 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.031406 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0308441 |
| EMP1 | epithelial membrane protein 1 | -0.0307563 |
| ASPH | aspartate beta-hydroxylase | -0.0304217 |
| SVIL | supervillin | -0.0302577 |
| ANXA1 | annexin A1 | -0.0302255 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0297191 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0297059 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0290026 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0287116 |
| LAMC2 | laminin, gamma 2 | -0.0280724 |
| LAMB3 | laminin, beta 3 | -0.0278735 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0278706 |
| JUN | jun proto-oncogene | -0.0274407 |
| CRY1 | cryptochrome circadian clock 1 | -0.0270695 |
| FMNL2 | formin-like 2 | -0.0268407 |
| DIAPH1 | diaphanous-related formin 1 | -0.0267808 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0263327 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0259203 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0255467 |
| RPL35A | ribosomal protein L35a | -0.0254176 |
| FLNB | filamin B, beta | -0.0251162 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0245551 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0244541 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0244306 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0241961 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0240401 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0239104 |
| RORA | RAR-related orphan receptor A | -0.0238001 |
| SQSTM1 | sequestosome 1 | -0.0234047 |
| USP53 | ubiquitin specific peptidase 53 | -0.0233442 |
| SH3D19 | SH3 domain containing 19 | -0.0232272 |
| KLF6 | Kruppel-like factor 6 | -0.0230847 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0226705 |
| FAT1 | FAT atypical cadherin 1 | -0.0221845 |
| GRB10 | growth factor receptor-bound protein 10 | -0.022126 |
| CRACD | capping protein inhibiting regulator of actin dynamics | -0.0220498 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0220087 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0219952 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0217893 |
| PARD3 | par-3 family cell polarity regulator | -0.0217889 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0216587 |
| DIAPH2 | diaphanous-related formin 2 | -0.0216368 |
| MLF1 | myeloid leukemia factor 1 | -0.0215991 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0214612 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0212438 |
| PER2 | period circadian clock 2 | -0.021121 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0211143 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.0210568 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0210124 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0210009 |
| VCAN | versican | -0.0209639 |
| CSTB | cystatin B (stefin B) | -0.020776 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0207464 |
| TUBA1B | tubulin, alpha 1b | -0.0206943 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0202908 |
