| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.201746 |
| SMYD3 | SET and MYND domain containing 3 | 0.090435 |
| RTN4 | reticulon 4 | 0.0627128 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0570941 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0542932 |
| PRELID2 | PRELI domain containing 2 | 0.0537236 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0518018 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0501375 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0496169 |
| GOLGA4 | golgin A4 | 0.0494153 |
| TXNIP | thioredoxin interacting protein | 0.0481399 |
| CUL5 | cullin 5 | 0.0461914 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.045468 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0447405 |
| NDRG1 | N-myc downstream regulated 1 | 0.0446715 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0443435 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0442172 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0437468 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0432694 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0421071 |
| NBAS | neuroblastoma amplified sequence | 0.0397005 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0394088 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0392672 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0386041 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0383433 |
| STK38 | serine/threonine kinase 38 | 0.0371231 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0371189 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0366116 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0361519 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0351713 |
| CCDC88A | coiled-coil domain containing 88A | 0.0349894 |
| KIAA1328 | KIAA1328 | 0.0345252 |
| UBXN4 | UBX domain protein 4 | 0.0344817 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0343967 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0341023 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0334707 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0332463 |
| SCFD1 | sec1 family domain containing 1 | 0.0329756 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0328038 |
| ATM | ATM serine/threonine kinase | 0.0327323 |
| CDCP1 | CUB domain containing protein 1 | 0.0321602 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0320171 |
| FRYL | FRY-like | 0.0318835 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0310109 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0307543 |
| SEC24A | SEC24 family member A | 0.030698 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0304636 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0302335 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0298761 |
| ORC3 | origin recognition complex, subunit 3 | 0.0296508 |
| GPHN | gephyrin | 0.0288673 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0285406 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0284073 |
| MORF4L2 | mortality factor 4 like 2 | 0.0284058 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0280572 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0280419 |
| ATXN3 | ataxin 3 | 0.0275636 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0275173 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0274133 |
| BBX | bobby sox homolog (Drosophila) | 0.0273528 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0272756 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0270572 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0269866 |
| FNIP1 | folliculin interacting protein 1 | 0.026941 |
| MEF2A | myocyte enhancer factor 2A | 0.0268959 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0268129 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0267744 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0267248 |
| IL6ST | interleukin 6 signal transducer | 0.0266983 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0265194 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0264265 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0261458 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.026128 |
| TTBK2 | tau tubulin kinase 2 | 0.0260321 |
| HADHB | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 0.0257661 |
| ACAD11 | acyl-CoA dehydrogenase family, member 11 | 0.0256656 |
| ZNF292 | zinc finger protein 292 | 0.0256606 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0254525 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.025302 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0251504 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0250052 |
| KIAA1958 | KIAA1958 | 0.0249908 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0248653 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0247384 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0246148 |
| SNX14 | sorting nexin 14 | 0.024603 |
| NKTR | natural killer cell triggering receptor | 0.0245183 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0243745 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0240558 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.023886 |
| TAOK3 | TAO kinase 3 | 0.0237833 |
| RANBP9 | RAN binding protein 9 | 0.0237805 |
| NBEAL1 | neurobeachin-like 1 | 0.0234794 |
| FBXO28 | F-box protein 28 | 0.02347 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0233862 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0233455 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0233365 |
| PNN | pinin, desmosome associated protein | 0.0231985 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.02319 |
| CFDP1 | craniofacial development protein 1 | 0.023174 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0774531 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0646617 |
| PTMA | prothymosin, alpha | -0.0617441 |
| LDHA | lactate dehydrogenase A | -0.0612713 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0586722 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.053231 |
| ANXA2 | annexin A2 | -0.0525949 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0512924 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0497283 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0493853 |
| VCL | vinculin | -0.0476153 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0471015 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.044871 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0430383 |
| AFDN | afadin, adherens junction formation factor | -0.0427809 |
| RPLP0 | ribosomal protein, large, P0 | -0.0405335 |
| DST | dystonin | -0.0400934 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0399436 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0396813 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0395069 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0394974 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0389992 |
| ATG7 | autophagy related 7 | -0.0386272 |
| CANX | calnexin | -0.038549 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0383374 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0374185 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0350281 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0344565 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0343702 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0341954 |
| QKI | QKI, KH domain containing, RNA binding | -0.0330271 |
| RACK1 | receptor for activated C kinase 1 | -0.0328216 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.032502 |
| MAP1B | microtubule-associated protein 1B | -0.0322407 |
| TPX2 | TPX2, microtubule-associated | -0.0319908 |
| FMNL2 | formin-like 2 | -0.0318523 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0317081 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0316943 |
| SVIL | supervillin | -0.0312545 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.031149 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0300764 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0299656 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.029947 |
| RPL36 | ribosomal protein L36 | -0.0298947 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0294782 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0293767 |
| PGK1 | phosphoglycerate kinase 1 | -0.028939 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0287318 |
| FAM13B | family with sequence similarity 13, member B | -0.0285898 |
| BRD2 | bromodomain containing 2 | -0.028427 |
| RAB10 | RAB10, member RAS oncogene family | -0.0282307 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0281735 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0280424 |
| TPI1 | triosephosphate isomerase 1 | -0.0279596 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0275531 |
| TCF12 | transcription factor 12 | -0.027463 |
| RAI14 | retinoic acid induced 14 | -0.0272086 |
| RPS12 | ribosomal protein S12 | -0.0271917 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0269067 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0268791 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0265207 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0263859 |
| RAD51B | RAD51 paralog B | -0.0262938 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0261602 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0259426 |
| FTL | ferritin, light polypeptide | -0.025625 |
| CD9 | CD9 molecule | -0.0255097 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0253318 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0253169 |
| DENND5A | DENN/MADD domain containing 5A | -0.0250524 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0249964 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.024989 |
| RIOK3 | RIO kinase 3 | -0.0249461 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0246021 |
| ABI2 | abl-interactor 2 | -0.0245718 |
| INTS6 | integrator complex subunit 6 | -0.0245152 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0239908 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0238129 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0237653 |
| POTEF | POTE ankyrin domain family, member F | -0.0237077 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0235853 |
| AHNAK | AHNAK nucleoprotein | -0.0233134 |
| USP22 | ubiquitin specific peptidase 22 | -0.0230914 |
| B2M | beta-2-microglobulin | -0.0230065 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.022882 |
| RPL35 | ribosomal protein L35 | -0.0227861 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0227356 |
| PCNX2 | pecanex 2 | -0.0226827 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0226425 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.022607 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0224601 |
| FBXO11 | F-box protein 11 | -0.0223019 |
| FCHO2 | FCH domain only 2 | -0.0222055 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0221774 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0221158 |
| FMN1 | formin 1 | -0.0220667 |
| EGFR | epidermal growth factor receptor | -0.0219349 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0218144 |
| SMAD3 | SMAD family member 3 | -0.0217675 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0216427 |
