| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.307908 |
| NDRG1 | N-myc downstream regulated 1 | 0.0976431 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0941976 |
| FN1 | fibronectin 1 | 0.0918173 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0798771 |
| AHR | aryl hydrocarbon receptor | 0.0772544 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0767929 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0715884 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0640467 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0633132 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0630786 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0627268 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0614942 |
| OSMR | oncostatin M receptor | 0.0602494 |
| NRP1 | neuropilin 1 | 0.0597198 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0584423 |
| VEGFA | vascular endothelial growth factor A | 0.0544667 |
| FNDC3B | fibronectin type III domain containing 3B | 0.052983 |
| TMEM165 | transmembrane protein 165 | 0.0518957 |
| TXNIP | thioredoxin interacting protein | 0.0497096 |
| SMOX | spermine oxidase | 0.0484764 |
| GLIS3 | GLIS family zinc finger 3 | 0.0478902 |
| CD109 | CD109 molecule | 0.0474439 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0473824 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.045065 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.042912 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0426761 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.042175 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0412161 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0409518 |
| FAM3C | family with sequence similarity 3, member C | 0.0394285 |
| HMGA2 | high mobility group AT-hook 2 | 0.0390054 |
| COPA | coatomer protein complex, subunit alpha | 0.0383398 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0383101 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0380193 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0377784 |
| ETNK1 | ethanolamine kinase 1 | 0.0369783 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0368394 |
| RTN4 | reticulon 4 | 0.0365233 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0362496 |
| NKTR | natural killer cell triggering receptor | 0.0353347 |
| FNBP1 | formin binding protein 1 | 0.0349187 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0337373 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0334791 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0327177 |
| EFNA5 | ephrin-A5 | 0.032417 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0320385 |
| OGA | O-GlcNAcase | 0.0311417 |
| ETV6 | ets variant 6 | 0.0308847 |
| RUNX2 | runt-related transcription factor 2 | 0.0307303 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0305112 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0304711 |
| CCNL1 | cyclin L1 | 0.0303068 |
| DENND5B | DENN/MADD domain containing 5B | 0.0289266 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0285617 |
| IL6ST | interleukin 6 signal transducer | 0.0283773 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0282513 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0278959 |
| RNF145 | ring finger protein 145 | 0.0275286 |
| SUCO | SUN domain containing ossification factor | 0.0274631 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0274177 |
| UBXN4 | UBX domain protein 4 | 0.0271295 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0269736 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.026762 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0267559 |
| CDCP1 | CUB domain containing protein 1 | 0.0267308 |
| CDC73 | cell division cycle 73 | 0.0266917 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0265079 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0265077 |
| GPC6 | glypican 6 | 0.0263497 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0261665 |
| ADAR | adenosine deaminase, RNA-specific | 0.0261349 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0260977 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0258907 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0258724 |
| FOSL2 | FOS-like antigen 2 | 0.0258464 |
| SETD5 | SET domain containing 5 | 0.0254592 |
| SFXN1 | sideroflexin 1 | 0.025316 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0250287 |
| AFDN | afadin, adherens junction formation factor | 0.0248381 |
| CAB39 | calcium binding protein 39 | 0.024718 |
| XPO1 | exportin 1 | 0.024602 |
| PDE8A | phosphodiesterase 8A | 0.0245442 |
| HELZ | helicase with zinc finger | 0.0245417 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0244756 |
| GOLGA4 | golgin A4 | 0.0244589 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0244082 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0243133 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0241851 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0240719 |
| SYNJ2 | synaptojanin 2 | 0.02386 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0237147 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0237122 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0236414 |
| VCL | vinculin | 0.023637 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0236141 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0232419 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0231056 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0230056 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0228116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.197459 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.126838 |
| NRG1 | neuregulin 1 | -0.123116 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.10985 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0985569 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0980263 |
| SQSTM1 | sequestosome 1 | -0.0967068 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0879889 |
| PTMA | prothymosin, alpha | -0.0841216 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0816605 |
| FTL | ferritin, light polypeptide | -0.0659043 |
| POTEF | POTE ankyrin domain family, member F | -0.0608677 |
| TMSB10 | thymosin beta 10 | -0.0569591 |
| MT2A | metallothionein 2A | -0.0556299 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0515992 |
| B2M | beta-2-microglobulin | -0.0502275 |
| RPL12 | ribosomal protein L12 | -0.0490606 |
| TMSB4X | thymosin beta 4, X-linked | -0.0490151 |
| ENO1 | enolase 1, (alpha) | -0.0481157 |
| RPL31 | ribosomal protein L31 | -0.0460717 |
| RPS12 | ribosomal protein S12 | -0.0459398 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0450617 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0435687 |
| TPI1 | triosephosphate isomerase 1 | -0.0432415 |
| VIM | vimentin | -0.0421225 |
| S100A6 | S100 calcium binding protein A6 | -0.0420718 |
| RACK1 | receptor for activated C kinase 1 | -0.0417518 |
| RPL35A | ribosomal protein L35a | -0.0413561 |
| RPL26 | ribosomal protein L26 | -0.0399522 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0368164 |
| ACTG1 | actin gamma 1 | -0.0359193 |
| STC2 | stanniocalcin 2 | -0.0356978 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0354306 |
| RPL23 | ribosomal protein L23 | -0.0344403 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0332646 |
| CADM1 | cell adhesion molecule 1 | -0.0329566 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.030978 |
| HLA-B | major histocompatibility complex, class I, B | -0.0300048 |
| FAT1 | FAT atypical cadherin 1 | -0.0291994 |
| RPS27 | ribosomal protein S27 | -0.0285441 |
| RPS27A | ribosomal protein S27a | -0.0284996 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284526 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0283486 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0282327 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0280682 |
| RPL37A | ribosomal protein L37a | -0.0278953 |
| RPS19 | ribosomal protein S19 | -0.0276083 |
| RPS8 | ribosomal protein S8 | -0.0273533 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0272456 |
| EREG | epiregulin | -0.0271507 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0270573 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267387 |
| TMEM156 | transmembrane protein 156 | -0.0265978 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0262249 |
| RPL11 | ribosomal protein L11 | -0.0257734 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0256726 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0256651 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0255924 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0255007 |
| INTS6 | integrator complex subunit 6 | -0.0253348 |
| RPL19 | ribosomal protein L19 | -0.0253132 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0252792 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0251719 |
| FAM107B | family with sequence similarity 107, member B | -0.0248935 |
| USP15 | ubiquitin specific peptidase 15 | -0.0247227 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0246258 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0246072 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0244387 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0242037 |
| FBN1 | fibrillin 1 | -0.0241397 |
| RPS24 | ribosomal protein S24 | -0.0239657 |
| RPLP0 | ribosomal protein, large, P0 | -0.0237035 |
| RPS6 | ribosomal protein S6 | -0.0235271 |
| CANX | calnexin | -0.0235249 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.023331 |
| CALR | calreticulin | -0.0231894 |
| IER3 | immediate early response 3 | -0.0230575 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0228652 |
| ARF1 | ADP-ribosylation factor 1 | -0.0227965 |
| RPL38 | ribosomal protein L38 | -0.0223647 |
| PGK1 | phosphoglycerate kinase 1 | -0.022229 |
| CCDC47 | coiled-coil domain containing 47 | -0.0222272 |
| RPS16 | ribosomal protein S16 | -0.0222141 |
| PLIN2 | perilipin 2 | -0.0220162 |
| S100A10 | S100 calcium binding protein A10 | -0.0217075 |
| SERINC1 | serine incorporator 1 | -0.0216521 |
| RPL37 | ribosomal protein L37 | -0.0216283 |
| STC1 | stanniocalcin 1 | -0.02159 |
| CRY1 | cryptochrome circadian clock 1 | -0.0213589 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0208826 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0208187 |
| RPL34 | ribosomal protein L34 | -0.0206331 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.020558 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0201566 |
| RPS3 | ribosomal protein S3 | -0.0200554 |
| RPLP2 | ribosomal protein, large, P2 | -0.0199487 |
| RPL9 | ribosomal protein L9 | -0.0197713 |
| MYOF | myoferlin | -0.0196121 |
| RPL13A | ribosomal protein L13a | -0.0194761 |
| LMNA | lamin A/C | -0.0194181 |
