| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0591585 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0513165 |
| GOLGA4 | golgin A4 | 0.0502469 |
| USP3 | ubiquitin specific peptidase 3 | 0.0482972 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0444521 |
| CCNL1 | cyclin L1 | 0.0424261 |
| MATR3 | matrin 3 | 0.0387228 |
| FAM3C | family with sequence similarity 3, member C | 0.0370258 |
| ZNF292 | zinc finger protein 292 | 0.0363126 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0350407 |
| RNF145 | ring finger protein 145 | 0.0337713 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0335487 |
| FTL | ferritin, light polypeptide | 0.0325611 |
| TFG | TRK-fused gene | 0.0319628 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0314134 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0307377 |
| RBM25 | RNA binding motif protein 25 | 0.030498 |
| NCKAP1 | NCK-associated protein 1 | 0.0293139 |
| XPO1 | exportin 1 | 0.0292718 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0285674 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0284408 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0284105 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.028327 |
| SEPTIN7 | septin 7 | 0.028186 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0279188 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0277909 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0274519 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0272893 |
| NKTR | natural killer cell triggering receptor | 0.0263137 |
| RNF149 | ring finger protein 149 | 0.023581 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0229345 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0227231 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0226886 |
| H1-0 | H1.0 linker histone | 0.0225878 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0225443 |
| RTN4 | reticulon 4 | 0.0219433 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0219314 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218718 |
| OGA | O-GlcNAcase | 0.0218526 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.021764 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0216556 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0213462 |
| SUCO | SUN domain containing ossification factor | 0.0212367 |
| TXNIP | thioredoxin interacting protein | 0.0212358 |
| PCBP2 | poly(rC) binding protein 2 | 0.0212134 |
| FNBP1L | formin binding protein 1-like | 0.020825 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0206423 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0206289 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0206205 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0202204 |
| PDS5B | PDS5 cohesin associated factor B | 0.0199655 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0198067 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0197842 |
| TPX2 | TPX2, microtubule-associated | 0.019626 |
| CST3 | cystatin C | 0.0193907 |
| ARRDC3 | arrestin domain containing 3 | 0.0188058 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0187724 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0186002 |
| SNX9 | sorting nexin 9 | 0.0184327 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0182578 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0177999 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0176549 |
| ZFP36 | ZFP36 ring finger protein | 0.017516 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0174818 |
| TXNRD1 | thioredoxin reductase 1 | 0.0174599 |
| RIOK3 | RIO kinase 3 | 0.0173672 |
| RAB18 | RAB18, member RAS oncogene family | 0.0173573 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0172558 |
| TMEM41B | transmembrane protein 41B | 0.0172248 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0170559 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0170554 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0168285 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0167697 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0166771 |
| CHMP2B | charged multivesicular body protein 2B | 0.0166145 |
| RDX | radixin | 0.0165474 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0165328 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.016523 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0164768 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0164248 |
| CENPF | centromere protein F, 350/400kDa | 0.0163936 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0163637 |
| PTEN | phosphatase and tensin homolog | 0.0161896 |
| MTF2 | metal response element binding transcription factor 2 | 0.0161871 |
| FMR1 | fragile X mental retardation 1 | 0.0159566 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0159477 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0158127 |
| NUP58 | nucleoporin 58 | 0.0157611 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0157217 |
| ORC4 | origin recognition complex, subunit 4 | 0.0156617 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.015559 |
| RYK | receptor-like tyrosine kinase | 0.0154711 |
| SRP54 | signal recognition particle 54kDa | 0.0153822 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0152906 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0152238 |
| FOSL1 | FOS-like antigen 1 | 0.0151263 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0151075 |
| REPS1 | RALBP1 associated Eps domain containing 1 | 0.0150412 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0150056 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0149395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | -0.175003 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.174477 |
| BCL2L1 | BCL2-like 1 | -0.129959 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.129231 |
| VCL | vinculin | -0.107865 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.106288 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.104308 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0977867 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.097651 |
| EHBP1 | EH domain binding protein 1 | -0.0913651 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0879579 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0815163 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0787285 |
| MYO1E | myosin IE | -0.0780846 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.074249 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0741228 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0714499 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0712764 |
| IFRD1 | interferon-related developmental regulator 1 | -0.069263 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0664852 |
| ANXA2 | annexin A2 | -0.0655923 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0644505 |
| INTS6 | integrator complex subunit 6 | -0.0639769 |
| FAT1 | FAT atypical cadherin 1 | -0.0638671 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0621514 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0611809 |
| KRT18 | keratin 18, type I | -0.0605683 |
| CADPS | Ca++-dependent secretion activator | -0.0605056 |
| PATJ | PATJ crumbs cell polarity complex component | -0.05999 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0598663 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0597058 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0585865 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0582855 |
| KRT8 | keratin 8, type II | -0.0582577 |
| EXOC4 | exocyst complex component 4 | -0.0578909 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0578596 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0566593 |
| NEBL | nebulette | -0.0561362 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0546075 |
| AHNAK | AHNAK nucleoprotein | -0.0545346 |
| CDK13 | cyclin-dependent kinase 13 | -0.0538764 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0533279 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0530243 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0522239 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0514631 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.051278 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0511098 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0510481 |
| CUX1 | cut-like homeobox 1 | -0.0509227 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0503616 |
| RUNX1 | runt-related transcription factor 1 | -0.0501321 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0500592 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0496767 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0493516 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0490041 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0485259 |
| UBAP2 | ubiquitin associated protein 2 | -0.0476742 |
| SMAD3 | SMAD family member 3 | -0.0471943 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0465873 |
| GOLGB1 | golgin B1 | -0.0464164 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0458163 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0455938 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0443842 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0442586 |
| EGR1 | early growth response 1 | -0.0440973 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0439377 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0437312 |
| MYOF | myoferlin | -0.0432993 |
| OXSR1 | oxidative stress responsive 1 | -0.0430561 |
| PLSCR1 | phospholipid scramblase 1 | -0.0426584 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0425467 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0423024 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.042092 |
| ETV6 | ets variant 6 | -0.0416634 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0410247 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0409146 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0408259 |
| SMAD2 | SMAD family member 2 | -0.0402321 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0402177 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0400224 |
| PRELID2 | PRELI domain containing 2 | -0.0399679 |
| CMIP | c-Maf inducing protein | -0.0399159 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0397417 |
| TGFA | transforming growth factor, alpha | -0.0394846 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0393806 |
| WWC1 | WW and C2 domain containing 1 | -0.0392663 |
| EZR | ezrin | -0.0387418 |
| NFIA | nuclear factor I/A | -0.0381351 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0377974 |
| ACTN4 | actinin, alpha 4 | -0.0374887 |
| EGFR | epidermal growth factor receptor | -0.0374107 |
| RCOR1 | REST corepressor 1 | -0.0373744 |
| GPHN | gephyrin | -0.0373348 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0373142 |
| FRMD5 | FERM domain containing 5 | -0.0372899 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0367996 |
| TJP1 | tight junction protein 1 | -0.0362714 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0359309 |
| RAB10 | RAB10, member RAS oncogene family | -0.0357236 |
| RAD51B | RAD51 paralog B | -0.0353722 |
