| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbidopa (monohydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.18774 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.150506 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.136141 |
| AREG | amphiregulin | 0.107325 |
| ANXA1 | annexin A1 | 0.0996867 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0967611 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0844692 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0758675 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0744628 |
| NDRG1 | N-myc downstream regulated 1 | 0.0727205 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0633974 |
| RPS6 | ribosomal protein S6 | 0.0607704 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0590902 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0566161 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0543504 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0533222 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.053107 |
| OXR1 | oxidation resistance 1 | 0.0455749 |
| FAM3C | family with sequence similarity 3, member C | 0.0427916 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0427277 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0420937 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0413803 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0411504 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0398406 |
| EGR1 | early growth response 1 | 0.0395741 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0385032 |
| NUP58 | nucleoporin 58 | 0.0384021 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0373661 |
| GOLGA4 | golgin A4 | 0.0366786 |
| GDF15 | growth differentiation factor 15 | 0.0362338 |
| EREG | epiregulin | 0.0359575 |
| RNF145 | ring finger protein 145 | 0.0352903 |
| WAC | WW domain containing adaptor with coiled-coil | 0.034794 |
| RPS3 | ribosomal protein S3 | 0.0344907 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0344078 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0340719 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0338776 |
| PERP | PERP, TP53 apoptosis effector | 0.0337875 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0331425 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0327109 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0324373 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323257 |
| MT1X | metallothionein 1X | 0.0321346 |
| RPS17 | ribosomal protein S17 | 0.031867 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0305571 |
| RCOR1 | REST corepressor 1 | 0.0298664 |
| FOSL1 | FOS-like antigen 1 | 0.0295814 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0292585 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0288029 |
| COPA | coatomer protein complex, subunit alpha | 0.028482 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0284046 |
| CCNL1 | cyclin L1 | 0.0282757 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0279081 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0278157 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0277498 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0276788 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0275576 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0274601 |
| RPL21 | ribosomal protein L21 | 0.0273827 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0270815 |
| RPL31 | ribosomal protein L31 | 0.0266339 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0264105 |
| NEMF | nuclear export mediator factor | 0.0261576 |
| USP3 | ubiquitin specific peptidase 3 | 0.0261165 |
| SNX9 | sorting nexin 9 | 0.0259118 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0256983 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.025502 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0250496 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0249783 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0248397 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0247744 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0247721 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0236613 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0236491 |
| TRAM1 | translocation associated membrane protein 1 | 0.0236009 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0235346 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0234469 |
| RPS19 | ribosomal protein S19 | 0.0234314 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0233239 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0232371 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.023072 |
| RPS8 | ribosomal protein S8 | 0.0230598 |
| SETD5 | SET domain containing 5 | 0.0229324 |
| TXNIP | thioredoxin interacting protein | 0.0228911 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0227979 |
| RPL7A | ribosomal protein L7a | 0.0227229 |
| PNN | pinin, desmosome associated protein | 0.0226193 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0224525 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0221331 |
| KITLG | KIT ligand | 0.0220194 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0219662 |
| RPS13 | ribosomal protein S13 | 0.0218663 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0218158 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0215475 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0215334 |
| KLF9 | Kruppel-like factor 9 | 0.0215298 |
| THOC2 | THO complex 2 | 0.0214384 |
| UBE3A | ubiquitin protein ligase E3A | 0.0213659 |
| VMP1 | vacuole membrane protein 1 | 0.0213256 |
| SRP54 | signal recognition particle 54kDa | 0.0210396 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.194735 |
| EGFR | epidermal growth factor receptor | -0.161716 |
| LMO7 | LIM domain 7 | -0.107988 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0744667 |
| LAMC2 | laminin, gamma 2 | -0.072093 |
| LAMB3 | laminin, beta 3 | -0.0709372 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0670281 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0653249 |
| TXNRD1 | thioredoxin reductase 1 | -0.0625407 |
| FAT1 | FAT atypical cadherin 1 | -0.061823 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0599526 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0505759 |
| RNF43 | ring finger protein 43 | -0.049458 |
| FHL2 | four and a half LIM domains 2 | -0.0491556 |
| SMAD3 | SMAD family member 3 | -0.0449716 |
| FERMT1 | fermitin family member 1 | -0.0444673 |
| MTAP | methylthioadenosine phosphorylase | -0.0442897 |
| ACTN4 | actinin, alpha 4 | -0.0441874 |
| RAD51B | RAD51 paralog B | -0.0430433 |
| KLF6 | Kruppel-like factor 6 | -0.0425774 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0423005 |
| SEPTIN9 | septin 9 | -0.0412498 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0412135 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0407077 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0406455 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.039708 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0379757 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.036842 |
| DUSP4 | dual specificity phosphatase 4 | -0.0366632 |
| RPS24 | ribosomal protein S24 | -0.036575 |
| AHNAK | AHNAK nucleoprotein | -0.0364641 |
| VCL | vinculin | -0.0363519 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0362523 |
| RPL4 | ribosomal protein L4 | -0.0361652 |
| YAP1 | Yes-associated protein 1 | -0.0358674 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0351463 |
| HDAC2 | histone deacetylase 2 | -0.0341953 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0340144 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0331151 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0325024 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0318337 |
| TNS3 | tensin 3 | -0.0318049 |
| EZR | ezrin | -0.0315968 |
| PRELID2 | PRELI domain containing 2 | -0.0314914 |
| MSI2 | musashi RNA-binding protein 2 | -0.0313618 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0313103 |
| HMGA2 | high mobility group AT-hook 2 | -0.030931 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0309183 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0307522 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0305824 |
| SMYD3 | SET and MYND domain containing 3 | -0.0305303 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0305151 |
| SDC4 | syndecan 4 | -0.0301837 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0300997 |
| TOP1 | topoisomerase (DNA) I | -0.0297989 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0297197 |
| TUBB | tubulin, beta class I | -0.029626 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.029495 |
| TET3 | tet methylcytosine dioxygenase 3 | -0.0293426 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0290138 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0289966 |
| HDLBP | high density lipoprotein binding protein | -0.0288838 |
| CDK13 | cyclin-dependent kinase 13 | -0.0281762 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0278481 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0276472 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0275198 |
| EXOC6B | exocyst complex component 6B | -0.0274909 |
| RAB10 | RAB10, member RAS oncogene family | -0.0271712 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0271407 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.0270213 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.027021 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0269735 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0266672 |
| SQSTM1 | sequestosome 1 | -0.0262276 |
| HMGB2 | high mobility group box 2 | -0.0260465 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0258417 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0255406 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0251826 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0250477 |
| SPATA13 | spermatogenesis associated 13 | -0.0248198 |
| DOCK1 | dedicator of cytokinesis 1 | -0.024765 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0247362 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0246923 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0246411 |
| AXIN2 | axin 2 | -0.0245819 |
| ARF1 | ADP-ribosylation factor 1 | -0.0244259 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0236889 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0235895 |
| CLTC | clathrin, heavy chain (Hc) | -0.0235004 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0234595 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0234452 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0232641 |
| SERINC5 | serine incorporator 5 | -0.0231954 |
| CUL1 | cullin 1 | -0.0231921 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0231682 |
| KIAA0040 | KIAA0040 | -0.0231247 |
| EXOC4 | exocyst complex component 4 | -0.0230486 |
| DSPP | dentin sialophosphoprotein | -0.0229343 |
| MKI67 | marker of proliferation Ki-67 | -0.0228062 |
| AOPEP | aminopeptidase O (putative) | -0.022771 |
