| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbidopa (monohydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.112385 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0824911 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0804214 |
| ZNF292 | zinc finger protein 292 | 0.0792588 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0675743 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0656798 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0599573 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0576118 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0559047 |
| KIZ | kizuna centrosomal protein | 0.053613 |
| PCBP2 | poly(rC) binding protein 2 | 0.0529015 |
| ANLN | anillin, actin binding protein | 0.0492302 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0485117 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0484045 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.046569 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0460175 |
| TXNIP | thioredoxin interacting protein | 0.044506 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0439541 |
| TNS4 | tensin 4 | 0.0423779 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0410855 |
| NDRG1 | N-myc downstream regulated 1 | 0.0409934 |
| DIAPH3 | diaphanous-related formin 3 | 0.0407708 |
| OXR1 | oxidation resistance 1 | 0.0397785 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0389602 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0388844 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0387902 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0370858 |
| PGK1 | phosphoglycerate kinase 1 | 0.0368521 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0362926 |
| XPO1 | exportin 1 | 0.0359036 |
| ABHD2 | abhydrolase domain containing 2 | 0.0348355 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0346 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0343767 |
| PCM1 | pericentriolar material 1 | 0.0335025 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0333657 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0331732 |
| USP34 | ubiquitin specific peptidase 34 | 0.0327497 |
| CDK19 | cyclin-dependent kinase 19 | 0.0324955 |
| PHF21A | PHD finger protein 21A | 0.0324163 |
| PTEN | phosphatase and tensin homolog | 0.0322641 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0322588 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0320966 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0318249 |
| NUP58 | nucleoporin 58 | 0.0311146 |
| CDK8 | cyclin-dependent kinase 8 | 0.0310966 |
| FNIP1 | folliculin interacting protein 1 | 0.030166 |
| ZNF638 | zinc finger protein 638 | 0.0300845 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0294049 |
| YEATS2 | YEATS domain containing 2 | 0.0291577 |
| GOLGA4 | golgin A4 | 0.0290613 |
| OGA | O-GlcNAcase | 0.0287773 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0278466 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0270652 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0269261 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0268044 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0266205 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | 0.026219 |
| MED13L | mediator complex subunit 13-like | 0.0261903 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0260047 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0258655 |
| ETNK1 | ethanolamine kinase 1 | 0.0258491 |
| INSIG2 | insulin induced gene 2 | 0.0256385 |
| PDE8A | phosphodiesterase 8A | 0.0256094 |
| SBF2 | SET binding factor 2 | 0.0254897 |
| HELZ | helicase with zinc finger | 0.0253986 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0253586 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0252869 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.025176 |
| SETD5 | SET domain containing 5 | 0.0247684 |
| RNF24 | ring finger protein 24 | 0.0246659 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0242865 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0242707 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0241358 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0240413 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.023795 |
| PHIP | pleckstrin homology domain interacting protein | 0.0236294 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0235674 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0235392 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.023053 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0229891 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0228904 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0228528 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0226099 |
| COPA | coatomer protein complex, subunit alpha | 0.0224101 |
| MSN | moesin | 0.0223602 |
| CBX5 | chromobox homolog 5 | 0.0221407 |
| TPD52 | tumor protein D52 | 0.0220159 |
| USP33 | ubiquitin specific peptidase 33 | 0.0219826 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0219597 |
| WASF2 | WAS protein family, member 2 | 0.0219223 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0218958 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0218471 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0217233 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0216339 |
| CDCP1 | CUB domain containing protein 1 | 0.0216287 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0214476 |
| PKM | pyruvate kinase, muscle | 0.0213827 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0211002 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0210568 |
| CEP57 | centrosomal protein 57kDa | 0.0210154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.294368 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.111387 |
| CDH13 | cadherin 13 | -0.0978099 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0947336 |
| VCL | vinculin | -0.0875316 |
| LMO7 | LIM domain 7 | -0.0825108 |
| TMSB10 | thymosin beta 10 | -0.0793347 |
| SPATA13 | spermatogenesis associated 13 | -0.0789994 |
| ANXA2 | annexin A2 | -0.074637 |
| CCND1 | cyclin D1 | -0.0742907 |
| RPL35A | ribosomal protein L35a | -0.0740444 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0738671 |
| EZR | ezrin | -0.0735604 |
| ACTG1 | actin gamma 1 | -0.0641385 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0577457 |
| ACTN4 | actinin, alpha 4 | -0.056182 |
| SYT1 | synaptotagmin I | -0.0551462 |
| CDK6 | cyclin-dependent kinase 6 | -0.0543879 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0535506 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0533026 |
| INTS6 | integrator complex subunit 6 | -0.0524781 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0507931 |
| RPLP1 | ribosomal protein, large, P1 | -0.0505547 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0493718 |
| FRMD5 | FERM domain containing 5 | -0.0480774 |
| TNS3 | tensin 3 | -0.0479191 |
| FTL | ferritin, light polypeptide | -0.0477176 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0476907 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0468517 |
| BCL2L1 | BCL2-like 1 | -0.0467987 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0464496 |
| RPL23 | ribosomal protein L23 | -0.04565 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0442885 |
| RPL26 | ribosomal protein L26 | -0.0431428 |
| PTMA | prothymosin, alpha | -0.0426707 |
| SQSTM1 | sequestosome 1 | -0.0422492 |
| MTAP | methylthioadenosine phosphorylase | -0.0413477 |
| DST | dystonin | -0.041076 |
| RPS24 | ribosomal protein S24 | -0.0405382 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0402169 |
| KRT18 | keratin 18, type I | -0.0386097 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.038332 |
| RPS19 | ribosomal protein S19 | -0.0382595 |
| RPS8 | ribosomal protein S8 | -0.037646 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0376052 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0367068 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0364072 |
| EGR1 | early growth response 1 | -0.0363699 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0363624 |
| AHNAK | AHNAK nucleoprotein | -0.0360573 |
| PLEC | plectin | -0.0353896 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0351791 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.035143 |
| RPL4 | ribosomal protein L4 | -0.0349163 |
| RPL31 | ribosomal protein L31 | -0.0346886 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0342191 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.034172 |
| COBL | cordon-bleu WH2 repeat protein | -0.0337576 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0335706 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0331033 |
| RPL12 | ribosomal protein L12 | -0.0324619 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0322971 |
| RPL38 | ribosomal protein L38 | -0.0321329 |
| SMAD3 | SMAD family member 3 | -0.0317307 |
| RPS27A | ribosomal protein S27a | -0.0313556 |
| NOP56 | NOP56 ribonucleoprotein | -0.031205 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0308082 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0306151 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0303635 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0303599 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0301579 |
| MYO1E | myosin IE | -0.0300741 |
| TMEM163 | transmembrane protein 163 | -0.0299579 |
| FUS | FUS RNA binding protein | -0.0297974 |
| RPL13A | ribosomal protein L13a | -0.0294857 |
| SMYD3 | SET and MYND domain containing 3 | -0.028977 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0288924 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0285941 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283861 |
| EMP1 | epithelial membrane protein 1 | -0.0282398 |
| LAMA4 | laminin, alpha 4 | -0.0277422 |
| NAV2 | neuron navigator 2 | -0.02774 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0276975 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0276045 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0271276 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.027121 |
| RUNX1 | runt-related transcription factor 1 | -0.0270974 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.026334 |
| IER3 | immediate early response 3 | -0.0263214 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0260934 |
| RPL36A | ribosomal protein L36a | -0.0258587 |
| WDR43 | WD repeat domain 43 | -0.0256965 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0255586 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0254913 |
| IPO7 | importin 7 | -0.0254372 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.025314 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0249748 |
| EFNB2 | ephrin-B2 | -0.0248379 |
| RAD51B | RAD51 paralog B | -0.0247982 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0247038 |
