Carboplatin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A platinum coordination entity with cis square-planar geometry in which platinum(II) is coordinated to two ammonia ligands and a bidentate cyclobutane-1,1-dicarboxylate ligand. (Chemical Entities of Biological Interest Ontology, CHEBI_31355)
External Link http://ctdbase.org/detail.go?type=chem&acc=D016190
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Genes

46 genes/proteins interacting with the chemical Carboplatin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC2 baculoviral IAP repeat containing 2
BRCA1 breast cancer 1, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CYCS cytochrome c, somatic
DCT dopachrome tautomerase
EPCAM epithelial cell adhesion molecule
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
FSHB follicle stimulating hormone, beta polypeptide
GSR glutathione reductase
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
HAX1 HCLS1 associated protein X-1
HMOX1 heme oxygenase 1
IL6 interleukin 6
IL6R interleukin 6 receptor
KLK3 kallikrein-related peptidase 3
MPO myeloperoxidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PARP1 poly (ADP-ribose) polymerase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM17 RNA binding motif protein 17
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STX2 syntaxin 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNF tumor necrosis factor
TP53 tumor protein p53
XDH xanthine dehydrogenase