Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2127
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Genes

600 genes differentially expressed during Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
TMEM41B transmembrane protein 41B 3.6355
USP20 ubiquitin specific peptidase 20 3.3579
ZNF260 zinc finger protein 260 3.25446
RRAS related RAS viral (r-ras) oncogene homolog 3.22342
SERF2 small EDRK-rich factor 2 3.10179
ARF1 ADP-ribosylation factor 1 3.02037
SNX4 sorting nexin 4 2.9243
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.9193
KRT18 keratin 18, type I 2.88204
TM9SF4 transmembrane 9 superfamily protein member 4 2.83836
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2.83557
BZW1 basic leucine zipper and W2 domains 1 2.83134
SDCBP syndecan binding protein (syntenin) 2.76379
C1ORF52 chromosome 1 open reading frame 52 2.74539
NEK2 NIMA-related kinase 2 2.74536
PLIN3 perilipin 3 2.72887
MEOX1 mesenchyme homeobox 1 2.67621
REEP5 receptor accessory protein 5 2.66062
C9ORF64 chromosome 9 open reading frame 64 2.62844
WWTR1 WW domain containing transcription regulator 1 2.62815
ZNHIT1 zinc finger, HIT-type containing 1 2.62655
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 2.62473
KCTD10 potassium channel tetramerization domain containing 10 2.59979
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 2.59373
FKBP1A FK506 binding protein 1A, 12kDa 2.58493
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 2.57944
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.55496
NFE2L2 nuclear factor, erythroid 2-like 2 2.52811
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.51628
RHOC ras homolog family member C 2.51391
BCAR1 breast cancer anti-estrogen resistance 1 2.50292
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.47162
MYADM myeloid-associated differentiation marker 2.4621
CTRC chymotrypsin C (caldecrin) 2.45109
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 2.44784
MYO18A myosin XVIIIA 2.4005
TUBA1B tubulin, alpha 1b 2.39445
TWF1 twinfilin actin binding protein 1 2.38602
NAGK N-acetylglucosamine kinase 2.37078
MYO9B myosin IXB 2.36723
C1GALT1C1 C1GALT1-specific chaperone 1 2.36361
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 2.36091
IFIH1 interferon induced with helicase C domain 1 2.35779
PLSCR1 phospholipid scramblase 1 2.35488
WDR1 WD repeat domain 1 2.34192
TPD52 tumor protein D52 2.32846
YY1 YY1 transcription factor 2.31664
HSBP1 heat shock factor binding protein 1 2.30937
MCM5 minichromosome maintenance complex component 5 2.30713
COPA coatomer protein complex, subunit alpha 2.30579
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.30405
PDLIM7 PDZ and LIM domain 7 (enigma) 2.3006
TPP1 tripeptidyl peptidase I 2.28366
CLPTM1L CLPTM1-like 2.2752
HEXA hexosaminidase A (alpha polypeptide) 2.27461
ZWINT ZW10 interacting kinetochore protein 2.27391
PGM2 phosphoglucomutase 2 2.26735
ANTXR2 anthrax toxin receptor 2 2.24466
CTDNEP1 CTD nuclear envelope phosphatase 1 2.21021
MYL12B myosin, light chain 12B, regulatory 2.20672
SEPT8 septin 8 2.20375
CDK4 cyclin-dependent kinase 4 2.18477
PHOX2A paired-like homeobox 2a 2.17904
USP9X ubiquitin specific peptidase 9, X-linked 2.17852
C15ORF40 chromosome 15 open reading frame 40 2.17173
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.17152
CCNB1 cyclin B1 2.16635
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 2.16098
S1PR4 sphingosine-1-phosphate receptor 4 2.15898
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.15818
SCAMP5 secretory carrier membrane protein 5 2.1572
CEP19 centrosomal protein 19kDa 2.15294
NCKAP1 NCK-associated protein 1 2.14871
TSPO translocator protein (18kDa) 2.13897
TMEM62 transmembrane protein 62 2.13125
GTPBP2 GTP binding protein 2 2.1228
RAB20 RAB20, member RAS oncogene family 2.11169
GMFB glia maturation factor, beta 2.11087
UBE2C ubiquitin-conjugating enzyme E2C 2.09229
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 2.08713
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.07128
CTSD cathepsin D 2.07052
TMEM9B TMEM9 domain family, member B 2.06591
PRELID1 PRELI domain containing 1 2.06376
HIST1H1C histone cluster 1, H1c 2.06061
SYT12 synaptotagmin XII 2.05747
PRUNE prune exopolyphosphatase 2.04628
CENPT centromere protein T 2.02782
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 2.02323
CAMK1 calcium/calmodulin-dependent protein kinase I 2.02138
SPP2 secreted phosphoprotein 2, 24kDa 2.00406
CPLX2 complexin 2 1.993
CYTH1 cytohesin 1 1.99017
FEM1B fem-1 homolog b (C. elegans) 1.98779
KIAA0319L KIAA0319-like 1.98694
MAP2K7 mitogen-activated protein kinase kinase 7 1.98199
TUSC3 tumor suppressor candidate 3 1.96848
OTUD7B OTU deubiquitinase 7B 1.96672
SKA2 spindle and kinetochore associated complex subunit 2 1.96457
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.95307
CHMP4B charged multivesicular body protein 4B 1.94424
CD82 CD82 molecule 1.94238
EIF6 eukaryotic translation initiation factor 6 1.94017
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.93916
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.93698
NHP2 NHP2 ribonucleoprotein 1.9352
PEA15 phosphoprotein enriched in astrocytes 15 1.93343
FBXO11 F-box protein 11 1.93295
ACTA2 actin, alpha 2, smooth muscle, aorta 1.93181
NPC2 Niemann-Pick disease, type C2 1.92821
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 1.92452
SPG11 spastic paraplegia 11 (autosomal recessive) 1.9165
CD93 CD93 molecule 1.89826
PITPNA phosphatidylinositol transfer protein, alpha 1.8917
LTN1 listerin E3 ubiquitin protein ligase 1 1.89008
SCYL1 SCY1-like 1 (S. cerevisiae) 1.88536
WARS tryptophanyl-tRNA synthetase 1.88118
TMC6 transmembrane channel-like 6 1.87934
UNC5B unc-5 homolog B (C. elegans) 1.87732
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.8772
HSPA8 heat shock 70kDa protein 8 1.87689
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 1.8749
SLC39A11 solute carrier family 39, member 11 1.87213
SRD5A3 steroid 5 alpha-reductase 3 1.87184
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 1.8669
ARHGAP18 Rho GTPase activating protein 18 1.86539
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.86162
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.85904
LAMP1 lysosomal-associated membrane protein 1 1.85115
AFG3L2 AFG3-like AAA ATPase 2 1.84193
IL10RB interleukin 10 receptor, beta 1.84002
MINA MYC induced nuclear antigen 1.83301
MPDU1 mannose-P-dolichol utilization defect 1 1.83268
CLN3 ceroid-lipofuscinosis, neuronal 3 1.83151
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.83063
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.82264
PRKCI protein kinase C, iota 1.8154
EHD4 EH-domain containing 4 1.81408
TMEM5 transmembrane protein 5 1.81332
ANXA7 annexin A7 1.80676
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.80469
SLC48A1 solute carrier family 48 (heme transporter), member 1 1.80098
MTMR2 myotubularin related protein 2 1.7965
SURF4 surfeit 4 1.79636
NOS3 nitric oxide synthase 3 (endothelial cell) 1.77947
CLTB clathrin, light chain B 1.7769
HUNK hormonally up-regulated Neu-associated kinase 1.77684
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.77352
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.76998
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.76954
NAIP NLR family, apoptosis inhibitory protein 1.76764
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.75971
TRAPPC2L trafficking protein particle complex 2-like 1.75529
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.75395
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.75244
COL4A1 collagen, type IV, alpha 1 1.74933
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 1.74933
CNN3 calponin 3, acidic 1.74428
BMPR1A bone morphogenetic protein receptor, type IA 1.74311
KANSL2 KAT8 regulatory NSL complex subunit 2 1.74024
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.73695
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.73617
ACTRT1 actin-related protein T1 1.72779
DLL4 delta-like 4 (Drosophila) 1.71671
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.71377
C16ORF58 chromosome 16 open reading frame 58 1.71282
SPRTN SprT-like N-terminal domain 1.7118
SEC23IP SEC23 interacting protein 1.71099
HMHA1 histocompatibility (minor) HA-1 1.71062
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.71031
UGP2 UDP-glucose pyrophosphorylase 2 1.70905
EIF4A1 eukaryotic translation initiation factor 4A1 1.70162
BCAM basal cell adhesion molecule (Lutheran blood group) 1.69278
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.68821
KANSL1 KAT8 regulatory NSL complex subunit 1 1.68611
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.68556
GOLGA7 golgin A7 1.68544
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.6838
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 1.68373
NDFIP2 Nedd4 family interacting protein 2 1.6826
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.68238
STARD3 StAR-related lipid transfer (START) domain containing 3 1.68212
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.68096
SAV1 salvador family WW domain containing protein 1 1.67577
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 1.67287
RAB43 RAB43, member RAS oncogene family 1.67052
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.66172
AXIN1 axin 1 1.65809
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 1.65388
CSNK1E casein kinase 1, epsilon 1.65166
TBC1D20 TBC1 domain family, member 20 1.65093
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.6501
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.65007
GABARAP GABA(A) receptor-associated protein 1.64971
MYBBP1A MYB binding protein (P160) 1a 1.64586
FUNDC1 FUN14 domain containing 1 1.64586
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 1.64577
MAGEE1 melanoma antigen family E1 1.64451
SORT1 sortilin 1 1.64169
BAX BCL2-associated X protein 1.64117
ACOT9 acyl-CoA thioesterase 9 1.63865
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 1.63626
HLA-E major histocompatibility complex, class I, E 1.63189
KLF3 Kruppel-like factor 3 (basic) 1.63022
WDR82 WD repeat domain 82 1.6291
RAB31 RAB31, member RAS oncogene family 1.62615
CUTA cutA divalent cation tolerance homolog (E. coli) 1.62411
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 1.62391
KLF6 Kruppel-like factor 6 1.62256
NR1D2 nuclear receptor subfamily 1, group D, member 2 1.62216
FBF1 Fas (TNFRSF6) binding factor 1 1.62081
GSS glutathione synthetase 1.61492
ICAM1 intercellular adhesion molecule 1 1.60972
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 1.60713
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.6019
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 1.60099
TMEM106A transmembrane protein 106A 1.59677
RNF141 ring finger protein 141 1.59599
TSC22D4 TSC22 domain family, member 4 1.59324
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.58707
GLMP glycosylated lysosomal membrane protein 1.58548
MCM3 minichromosome maintenance complex component 3 1.58498
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 1.58302
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.58159
ADGRG3 adhesion G protein-coupled receptor G3 1.58112
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 1.58065
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.57792
CYB5R1 cytochrome b5 reductase 1 1.56926
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.56721
COMTD1 catechol-O-methyltransferase domain containing 1 1.56664
SPNS1 spinster homolog 1 (Drosophila) 1.56563
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.56512
GPAA1 glycosylphosphatidylinositol anchor attachment 1 1.56456
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.56434
RALY RALY heterogeneous nuclear ribonucleoprotein 1.56384
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.56203
MKI67 marker of proliferation Ki-67 1.55648
C1D C1D nuclear receptor corepressor 1.55443
STRN3 striatin, calmodulin binding protein 3 1.54882
EIF4E eukaryotic translation initiation factor 4E 1.54642
LRRC59 leucine rich repeat containing 59 1.54486
ASXL1 additional sex combs like transcriptional regulator 1 1.54324
MRRF mitochondrial ribosome recycling factor 1.54286
ST7L suppression of tumorigenicity 7 like 1.5416
CCDC88A coiled-coil domain containing 88A 1.53858
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 1.53307
COMMD9 COMM domain containing 9 1.5287
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.52671
CRAMP1L Crm, cramped-like (Drosophila) 1.52664
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.52363
MYCBP MYC binding protein 1.51904
TMC4 transmembrane channel-like 4 1.51513
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 1.51496
RNF208 ring finger protein 208 1.51452
VGLL4 vestigial-like family member 4 1.5126
CALML4 calmodulin-like 4 1.51244
TXNDC9 thioredoxin domain containing 9 1.50922
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.50898
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 1.50701
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 1.50505
FAM126A family with sequence similarity 126, member A 1.50337
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.5017
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.49953
RPL13 ribosomal protein L13 1.49925
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.49437
ADD1 adducin 1 (alpha) 1.49392
SLC10A3 solute carrier family 10, member 3 1.49324
SERINC1 serine incorporator 1 1.49214
GRWD1 glutamate-rich WD repeat containing 1 1.48817
CTTN cortactin 1.48661
DYNLL1 dynein, light chain, LC8-type 1 1.48583
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1.48461
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.48071
PYGB phosphorylase, glycogen; brain 1.47901
METTL21A methyltransferase like 21A 1.47354
ALDOA aldolase A, fructose-bisphosphate 1.47321
DOLK dolichol kinase 1.47279
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 1.47228
BRCA2 breast cancer 2, early onset 1.47181
SMAD1 SMAD family member 1 1.47178
DNPEP aspartyl aminopeptidase 1.47039
SNAP23 synaptosomal-associated protein, 23kDa 1.47034
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 1.46604
SMC4 structural maintenance of chromosomes 4 1.46503
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.46288
SOCS5 suppressor of cytokine signaling 5 1.46158
C15ORF39 chromosome 15 open reading frame 39 1.46127
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 1.4596
H2AFX H2A histone family, member X 1.45661
C11ORF31 chromosome 11 open reading frame 31 1.45596
CYTH2 cytohesin 2 1.45451
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 1.45016
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.44879
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.44594
LIN7C lin-7 homolog C (C. elegans) 1.44401
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 1.44091
ESM1 endothelial cell-specific molecule 1 1.4385
LY96 lymphocyte antigen 96 1.43784
KANK3 KN motif and ankyrin repeat domains 3 1.43551
HMG20A high mobility group 20A 1.43397

decreased expression

Symbol Name Standardized Value
IYD iodotyrosine deiodinase -3.15137
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -3.11097
ADK adenosine kinase -2.98301
ACADVL acyl-CoA dehydrogenase, very long chain -2.9659
ANKRD33B ankyrin repeat domain 33B -2.89869
CAMLG calcium modulating ligand -2.83123
AKAP1 A kinase (PRKA) anchor protein 1 -2.78392
MRPS12 mitochondrial ribosomal protein S12 -2.77487
MRPL4 mitochondrial ribosomal protein L4 -2.74059
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -2.69107
NUP88 nucleoporin 88kDa -2.66209
SPNS2 spinster homolog 2 (Drosophila) -2.66124
C2ORF71 chromosome 2 open reading frame 71 -2.58376
MTMR4 myotubularin related protein 4 -2.52475
TPRKB TP53RK binding protein -2.48271
ECSIT ECSIT signalling integrator -2.47025
FUCA1 fucosidase, alpha-L- 1, tissue -2.46265
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -2.44521
MRPS2 mitochondrial ribosomal protein S2 -2.43746
AURKAIP1 aurora kinase A interacting protein 1 -2.43729
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.41556
RAP1A RAP1A, member of RAS oncogene family -2.40629
EMC6 ER membrane protein complex subunit 6 -2.39135
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.39053
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.36821
FERMT2 fermitin family member 2 -2.35112
MRPL39 mitochondrial ribosomal protein L39 -2.33258
ZMPSTE24 zinc metallopeptidase STE24 -2.31894
COL18A1 collagen, type XVIII, alpha 1 -2.29789
SARDH sarcosine dehydrogenase -2.28775
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.28625
CARKD carbohydrate kinase domain containing -2.2813
SYNJ2BP synaptojanin 2 binding protein -2.27711
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.27158
TMEM205 transmembrane protein 205 -2.26623
DDRGK1 DDRGK domain containing 1 -2.25642
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -2.24716
PPP6C protein phosphatase 6, catalytic subunit -2.2467
UBE2Z ubiquitin-conjugating enzyme E2Z -2.24567
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.2256
LYRM2 LYR motif containing 2 -2.2226
ENDOU endonuclease, polyU-specific -2.19945
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.19316
TTC36 tetratricopeptide repeat domain 36 -2.17589
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d -2.1681
COX18 COX18 cytochrome c oxidase assembly factor -2.1556
USMG5 up-regulated during skeletal muscle growth 5 homolog (mouse) -2.14357
NGFR nerve growth factor receptor -2.1426
CYC1 cytochrome c-1 -2.1083
FCGBP Fc fragment of IgG binding protein -2.10459
ATG7 autophagy related 7 -2.07302
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.07079
BCL2L2 BCL2-like 2 -2.03832
CLYBL citrate lyase beta like -2.00037
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 -1.9994
RAB17 RAB17, member RAS oncogene family -1.99906
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -1.99307
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -1.98768
MIB1 mindbomb E3 ubiquitin protein ligase 1 -1.98571
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.98356
REPIN1 replication initiator 1 -1.97938
ELP4 elongator acetyltransferase complex subunit 4 -1.97647
MPDZ multiple PDZ domain protein -1.97352
MTMR9 myotubularin related protein 9 -1.97224
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.96772
PCNP PEST proteolytic signal containing nuclear protein -1.96465
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -1.9459
LMAN2 lectin, mannose-binding 2 -1.9435
DCTN3 dynactin 3 (p22) -1.9424
PXMP2 peroxisomal membrane protein 2, 22kDa -1.94207
MARK1 MAP/microtubule affinity-regulating kinase 1 -1.9329
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -1.92864
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -1.92656
TMEM242 transmembrane protein 242 -1.90516
APOC4 apolipoprotein C-IV -1.90463
AKAP8L A kinase (PRKA) anchor protein 8-like -1.9028
TOLLIP toll interacting protein -1.89953
NRP1 neuropilin 1 -1.89166
CTSH cathepsin H -1.88344
CACUL1 CDK2-associated, cullin domain 1 -1.87743
NDFIP1 Nedd4 family interacting protein 1 -1.8723
FBL fibrillarin -1.86441
ARMC1 armadillo repeat containing 1 -1.85219
FANCL Fanconi anemia, complementation group L -1.84765
MSRA methionine sulfoxide reductase A -1.84402
PHB2 prohibitin 2 -1.84226
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -1.83693
ECI1 enoyl-CoA delta isomerase 1 -1.8294
TPRG1L tumor protein p63 regulated 1-like -1.8293
KIAA0141 KIAA0141 -1.82655
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -1.82013
FIZ1 FLT3-interacting zinc finger 1 -1.81923
ZDHHC4 zinc finger, DHHC-type containing 4 -1.81303
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -1.80945
PKD2 polycystic kidney disease 2 (autosomal dominant) -1.80556
EMG1 EMG1 N1-specific pseudouridine methyltransferase -1.80146
WRNIP1 Werner helicase interacting protein 1 -1.8009
STARD8 StAR-related lipid transfer (START) domain containing 8 -1.79313
SPOP speckle-type POZ protein -1.79048
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.78783
HPN hepsin -1.78579
METTL8 methyltransferase like 8 -1.77621
MED8 mediator complex subunit 8 -1.75875
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -1.75813
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -1.75759
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -1.75627
CEPT1 choline/ethanolamine phosphotransferase 1 -1.75564
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -1.75127
SEC14L2 SEC14-like 2 (S. cerevisiae) -1.74985
UBA1 ubiquitin-like modifier activating enzyme 1 -1.74679
IVD isovaleryl-CoA dehydrogenase -1.74303
PEX16 peroxisomal biogenesis factor 16 -1.73218
XPO4 exportin 4 -1.7224
PIPOX pipecolic acid oxidase -1.71859
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -1.71744
NINJ1 ninjurin 1 -1.71637
RNF103 ring finger protein 103 -1.71293
RNF144B ring finger protein 144B -1.70602
MRPS7 mitochondrial ribosomal protein S7 -1.7049
OPA1 optic atrophy 1 (autosomal dominant) -1.69858
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -1.69139
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -1.69067
RBPMS2 RNA binding protein with multiple splicing 2 -1.68891
SYTL2 synaptotagmin-like 2 -1.68853
KIAA0368 KIAA0368 -1.67837
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -1.67075
ACAA2 acetyl-CoA acyltransferase 2 -1.66964
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 -1.66643
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -1.66286
MZT2A mitotic spindle organizing protein 2A -1.66027
ADAMDEC1 ADAM-like, decysin 1 -1.65879
TYSND1 trypsin domain containing 1 -1.6567
CASD1 CAS1 domain containing 1 -1.65314
PROZ protein Z, vitamin K-dependent plasma glycoprotein -1.65306
NCOR1 nuclear receptor corepressor 1 -1.65063
SMC3 structural maintenance of chromosomes 3 -1.64974
ACAD8 acyl-CoA dehydrogenase family, member 8 -1.64732
KIAA0100 KIAA0100 -1.64725
MFAP2 microfibrillar-associated protein 2 -1.64367
PCCB propionyl CoA carboxylase, beta polypeptide -1.64281
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -1.64147
ISLR immunoglobulin superfamily containing leucine-rich repeat -1.63842
GGPS1 geranylgeranyl diphosphate synthase 1 -1.63189
PAN2 PAN2 poly(A) specific ribonuclease subunit -1.6291
ETHE1 ethylmalonic encephalopathy 1 -1.62623
ACO1 aconitase 1, soluble -1.6259
GJA5 gap junction protein, alpha 5, 40kDa -1.6234
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -1.61439
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -1.61108
SEC63 SEC63 homolog (S. cerevisiae) -1.61016
MRPL55 mitochondrial ribosomal protein L55 -1.60449
SCGB3A1 secretoglobin, family 3A, member 1 -1.60281
RNF167 ring finger protein 167 -1.60273
CTU1 cytosolic thiouridylase subunit 1 -1.60046
CAPRIN1 cell cycle associated protein 1 -1.59797
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.59104
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.58873
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.58692
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -1.58649
TMED2 transmembrane emp24 domain trafficking protein 2 -1.58394
RXFP2 relaxin/insulin-like family peptide receptor 2 -1.58131
DMGDH dimethylglycine dehydrogenase -1.58047
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.57818
PEX5 peroxisomal biogenesis factor 5 -1.57512
DERA deoxyribose-phosphate aldolase (putative) -1.57508
GALT galactose-1-phosphate uridylyltransferase -1.57456
CD302 CD302 molecule -1.57423
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -1.56656
SLC31A1 solute carrier family 31 (copper transporter), member 1 -1.56555
GLRX2 glutaredoxin 2 -1.5648
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.56224
F13B coagulation factor XIII, B polypeptide -1.56224
UBQLN4 ubiquilin 4 -1.55926
ELAC2 elaC ribonuclease Z 2 -1.55664
NRBF2 nuclear receptor binding factor 2 -1.55542
TMEM120B transmembrane protein 120B -1.54952
CDC37L1 cell division cycle 37-like 1 -1.54578
STARD10 StAR-related lipid transfer (START) domain containing 10 -1.54576
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -1.54384
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.54367
SCARB2 scavenger receptor class B, member 2 -1.54235
RNF214 ring finger protein 214 -1.53686
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.53628
DIAPH1 diaphanous-related formin 1 -1.53241
BHMT betaine--homocysteine S-methyltransferase -1.52796
PDS5A PDS5 cohesin associated factor A -1.52249
COMMD7 COMM domain containing 7 -1.51922
EMC10 ER membrane protein complex subunit 10 -1.51851
LASP1 LIM and SH3 protein 1 -1.51733
NFYC nuclear transcription factor Y, gamma -1.5163
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 -1.51545
ELAVL1 ELAV like RNA binding protein 1 -1.51344
WBP11 WW domain binding protein 11 -1.51287
SEC16A SEC16 homolog A (S. cerevisiae) -1.51279
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -1.51085
MKRN2 makorin ring finger protein 2 -1.51072
PPA2 pyrophosphatase (inorganic) 2 -1.50876
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -1.50776
COX5A cytochrome c oxidase subunit Va -1.50356
GDF9 growth differentiation factor 9 -1.50311
UQCRB ubiquinol-cytochrome c reductase binding protein -1.50004
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -1.4989
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.4974
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -1.4952
TADA2A transcriptional adaptor 2A -1.49471
WDR33 WD repeat domain 33 -1.48981
RHOT1 ras homolog family member T1 -1.48684
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) -1.48655
USP48 ubiquitin specific peptidase 48 -1.48289
HIPK3 homeodomain interacting protein kinase 3 -1.48012
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.4792
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -1.47911
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.47815
RANGRF RAN guanine nucleotide release factor -1.47681
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -1.47647
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -1.47251
RBP4 retinol binding protein 4, plasma -1.47226
FNBP4 formin binding protein 4 -1.47223
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.47177
PTCD2 pentatricopeptide repeat domain 2 -1.46903
ELP2 elongator acetyltransferase complex subunit 2 -1.46887
AADAT aminoadipate aminotransferase -1.46752
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -1.46697
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -1.46577
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit -1.465
SNF8 SNF8, ESCRT-II complex subunit -1.45706
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -1.45668
ASB6 ankyrin repeat and SOCS box containing 6 -1.45568
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -1.45332
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -1.45309
S100A1 S100 calcium binding protein A1 -1.45221
CTSF cathepsin F -1.45
PDCD7 programmed cell death 7 -1.45
DCAF11 DDB1 and CUL4 associated factor 11 -1.44376
WNT6 wingless-type MMTV integration site family, member 6 -1.44185
POLB polymerase (DNA directed), beta -1.44099
BCL2L15 BCL2-like 15 -1.4409
ACSL1 acyl-CoA synthetase long-chain family member 1 -1.43904
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 -1.43691
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -1.43585
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -1.4346
SOD2 superoxide dismutase 2, mitochondrial -1.43374
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) -1.43067
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -1.4272
RIBC1 RIB43A domain with coiled-coils 1 -1.42222
EIF4H eukaryotic translation initiation factor 4H -1.41889
MRPL14 mitochondrial ribosomal protein L14 -1.41871
DOLPP1 dolichyldiphosphatase 1 -1.41788
RBMS2 RNA binding motif, single stranded interacting protein 2 -1.41504
MBP myelin basic protein -1.41076
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -1.40912
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -1.40787
GRID2 glutamate receptor, ionotropic, delta 2 -1.40746
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -1.40685
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -1.4047
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -1.40438
WBSCR16 Williams-Beuren syndrome chromosome region 16 -1.40424
UVRAG UV radiation resistance associated -1.40397
MEN1 multiple endocrine neoplasia I -1.40269
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.40161
RAD50 RAD50 homolog (S. cerevisiae) -1.39959
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) -1.39928
ATG5 autophagy related 5 -1.39777
NCOA5 nuclear receptor coactivator 5 -1.3963
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.39575
RNMTL1 RNA methyltransferase like 1 -1.39504
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -1.3947
SYNE2 spectrin repeat containing, nuclear envelope 2 -1.39468
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -1.39342
TARS threonyl-tRNA synthetase -1.39235
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -1.39111
RNF130 ring finger protein 130 -1.38926
HPS3 Hermansky-Pudlak syndrome 3 -1.38832
PEX13 peroxisomal biogenesis factor 13 -1.38559
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) -1.38501
LIG3 ligase III, DNA, ATP-dependent -1.38489
SLC25A46 solute carrier family 25, member 46 -1.38331
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.38316
KCTD20 potassium channel tetramerization domain containing 20 -1.37924
SCP2 sterol carrier protein 2 -1.37789
RPH3A rabphilin 3A -1.37717
C19ORF66 chromosome 19 open reading frame 66 -1.37294
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -1.36983
TK2 thymidine kinase 2, mitochondrial -1.3676
MANBAL mannosidase, beta A, lysosomal-like -1.36645
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 -1.36506
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -1.36424
BRS3 bombesin-like receptor 3 -1.36222
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.36182
AHCTF1 AT hook containing transcription factor 1 -1.3611
TRIT1 tRNA isopentenyltransferase 1 -1.35985
GCAT glycine C-acetyltransferase -1.35713
C6ORF203 chromosome 6 open reading frame 203 -1.3536
MOCS2 molybdenum cofactor synthesis 2 -1.35177
STK16 serine/threonine kinase 16 -1.34995
CTNNBL1 catenin, beta like 1 -1.34913
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -1.34817
GNMT glycine N-methyltransferase -1.34664
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.3433
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) -1.34255
Funding