Carcinoma, Spindle-Cell Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0205697
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Genes

212 genes associated with the disease Carcinoma, Spindle-Cell in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACKR3 atypical chemokine receptor 3
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTB actin, beta
ACTG1 actin gamma 1
ACTN4 actinin, alpha 4
ADCY5 adenylate cyclase 5
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL4 angiopoietin-like 4
ANXA1 annexin A1
ANXA4 annexin A4
AQP1 aquaporin 1 (Colton blood group)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP5IF1 ATP synthase inhibitory factor subunit 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
AZIN2 antizyme inhibitor 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BASP1 brain abundant, membrane attached signal protein 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C1ORF228 chromosome 1 open reading frame 228
CAPZB capping protein (actin filament) muscle Z-line, beta
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCND1 cyclin D1
CCNH cyclin H
CD274 CD274 molecule
CD47 CD47 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CKAP4 cytoskeleton-associated protein 4
CNN3 calponin 3, acidic
COL5A1 collagen, type V, alpha 1
CORO1A coronin, actin binding protein, 1A
COX1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSN2 casein beta
CSN3 casein kappa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYLD cylindromatosis (turban tumor syndrome)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DES desmin
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP6 dual specificity phosphatase 6
EBNA1BP2 EBNA1 binding protein 2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
EIF5A eukaryotic translation initiation factor 5A
ENG endoglin
ENO1 enolase 1, (alpha)
EPCAM epithelial cell adhesion molecule
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
FABP4 fatty acid binding protein 4, adipocyte
FHIT fragile histidine triad
FN1 fibronectin 1
FURIN furin (paired basic amino acid cleaving enzyme)
G0S2 G0/G1 switch 2
GADL1 glutamate decarboxylase-like 1
GATA3 GATA binding protein 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDA guanine deaminase
GEMIN2 gem (nuclear organelle) associated protein 2
GGT1 gamma-glutamyltransferase 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GSS glutathione synthetase
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H3F3B H3 histone, family 3B (H3.3B)
HBA1 hemoglobin, alpha 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HRAS Harvey rat sarcoma viral oncogene homolog
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IL6ST interleukin 6 signal transducer
IL9 interleukin 9
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INSIG1 insulin induced gene 1
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
KRT7 keratin 7, type II
KRT71 keratin 71, type II
KYAT1 kynurenine aminotransferase 1
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LGALS7 lectin, galactoside-binding, soluble, 7
LIN7A lin-7 homolog A (C. elegans)
LOXL2 lysyl oxidase-like 2
LPL lipoprotein lipase
LSR lipolysis stimulated lipoprotein receptor
LY96 lymphocyte antigen 96
MAPK1 mitogen-activated protein kinase 1
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPZL1 myelin protein zero-like 1
MRC2 mannose receptor, C type 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NANOG Nanog homeobox
NAPSA napsin A aspartic peptidase
NDN necdin, melanoma antigen (MAGE) family member
NKX2-1 NK2 homeobox 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUTM1 NUT midline carcinoma, family member 1
OXT oxytocin/neurophysin I prepropeptide
PADI4 peptidyl arginine deiminase, type IV
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGR progesterone receptor
PHB prohibitin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKM pyruvate kinase, muscle
PLAUR plasminogen activator, urokinase receptor
PLK2 polo-like kinase 2
PPARA peroxisome proliferator-activated receptor alpha
PRDX2 peroxiredoxin 2
PRLR prolactin receptor
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RABEPK Rab9 effector protein with kelch motifs
RAN RAN, member RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RB1 retinoblastoma 1
RBP1 retinol binding protein 1, cellular
RBP4 retinol binding protein 4, plasma
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHOA ras homolog family member A
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL3 ribosomal protein L3
RPL6 ribosomal protein L6
RPS14 ribosomal protein S14
RPSA ribosomal protein SA
S100A6 S100 calcium binding protein A6
S1PR1 sphingosine-1-phosphate receptor 1
SCAF11 SR-related CTD-associated factor 11
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAI1 snail family zinc finger 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SOD2 superoxide dismutase 2, mitochondrial
SOX9 SRY (sex determining region Y)-box 9
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRSF2 serine/arginine-rich splicing factor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STMN1 stathmin 1
TAZ tafazzin
TERT telomerase reverse transcriptase
TF transferrin
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THRSP thyroid hormone responsive
TKT transketolase
TLE4 transducin-like enhancer of split 4
TLR4 toll-like receptor 4
TMEM37 transmembrane protein 37
TP53 tumor protein p53
TP53I3 tumor protein p53 inducible protein 3
TP63 tumor protein p63
TPM3 tropomyosin 3
TRPS1 trichorhinophalangeal syndrome I
TSC22D1 TSC22 domain family, member 1
TSHR thyroid stimulating hormone receptor
TUBB2B tubulin, beta 2B class IIb
TYMP thymidine phosphorylase
UBE2I ubiquitin-conjugating enzyme E2I
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
URI1 URI1, prefoldin-like chaperone
UVRAG UV radiation resistance associated
VAMP8 vesicle-associated membrane protein 8
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
XDH xanthine dehydrogenase
YAP1 Yes-associated protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2