Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A type of malignant cancer that arises from epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (Experimental Factor Ontology, EFO_0000313)
External Link https://www.disgenet.org/browser/0/1/0/C1377904
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Genes

293 genes associated with the disease Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACKR3 atypical chemokine receptor 3
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTB actin, beta
ACTG1 actin gamma 1
ACTN4 actinin, alpha 4
ADCY5 adenylate cyclase 5
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALPK2 alpha-kinase 2
ANGPTL4 angiopoietin-like 4
ANXA1 annexin A1
ANXA4 annexin A4
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
AQP4 aquaporin 4
ARID1A AT rich interactive domain 1A (SWI-like)
ARID1B AT rich interactive domain 1B (SWI1-like)
ATM ATM serine/threonine kinase
ATOH1 atonal homolog 1 (Drosophila)
ATP5IF1 ATP synthase inhibitory factor subunit 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
B2M beta-2-microglobulin
BASP1 brain abundant, membrane attached signal protein 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CADM1 cell adhesion molecule 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCDC6 coiled-coil domain containing 6
CCL22 chemokine (C-C motif) ligand 22
CCND1 cyclin D1
CCNH cyclin H
CD163 CD163 molecule
CD1D CD1d molecule
CD274 CD274 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CDX2 caudal type homeobox 2
CHGB chromogranin B
CIRBP cold inducible RNA binding protein
CKAP4 cytoskeleton-associated protein 4
CLDN4 claudin 4
CNN3 calponin 3, acidic
COL5A1 collagen, type V, alpha 1
CORO1A coronin, actin binding protein, 1A
COX1
COX2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSN2 casein beta
CSN3 casein kappa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYLD cylindromatosis (turban tumor syndrome)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DES desmin
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPYD dihydropyrimidine dehydrogenase
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
EMD emerin
EMSY EMSY transcriptional repressor, BRCA2 interacting
ENO1 enolase 1, (alpha)
EPCAM epithelial cell adhesion molecule
EPHB1 EPH receptor B1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
F9 coagulation factor IX
FABP4 fatty acid binding protein 4, adipocyte
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHIT fragile histidine triad
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FURIN furin (paired basic amino acid cleaving enzyme)
G0S2 G0/G1 switch 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA3 GATA binding protein 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDA guanine deaminase
GGT1 gamma-glutamyltransferase 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPC3 glypican 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRP gastrin-releasing peptide
GSS glutathione synthetase
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H3F3B H3 histone, family 3B (H3.3B)
HBA1 hemoglobin, alpha 1
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IL10 interleukin 10
IL18 interleukin 18
IL22RA1 interleukin 22 receptor, alpha 1
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KITLG KIT ligand
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
KRT71 keratin 71, type II
KYAT1 kynurenine aminotransferase 1
LGALS7 lectin, galactoside-binding, soluble, 7
LIN7A lin-7 homolog A (C. elegans)
LMNA lamin A/C
LPAR1 lysophosphatidic acid receptor 1
LPL lipoprotein lipase
LSR lipolysis stimulated lipoprotein receptor
LY96 lymphocyte antigen 96
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK3 mitogen-activated protein kinase 3
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLH1 mutL homolog 1
MPZL1 myelin protein zero-like 1
MRC2 mannose receptor, C type 2
MRO maestro
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSLN mesothelin
MSN moesin
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA4 nuclear receptor coactivator 4
NDN necdin, melanoma antigen (MAGE) family member
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX2-1 NK2 homeobox 1
NOTCH1 notch 1
NPC1 Niemann-Pick disease, type C1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NUPR1 nuclear protein, transcriptional regulator, 1
NUTM1 NUT midline carcinoma, family member 1
OXT oxytocin/neurophysin I prepropeptide
PADI4 peptidyl arginine deiminase, type IV
PAX8 paired box 8
PCNA proliferating cell nuclear antigen
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PEBP1 phosphatidylethanolamine binding protein 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGR progesterone receptor
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKM pyruvate kinase, muscle
PLAUR plasminogen activator, urokinase receptor
PLK2 polo-like kinase 2
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDX2 peroxiredoxin 2
PRLR prolactin receptor
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTBP1 polypyrimidine tract binding protein 1
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RAN RAN, member RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RB1 retinoblastoma 1
RBP1 retinol binding protein 1, cellular
RBP4 retinol binding protein 4, plasma
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RET ret proto-oncogene
RHOA ras homolog family member A
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL3 ribosomal protein L3
RPL6 ribosomal protein L6
RPS14 ribosomal protein S14
RRAS related RAS viral (r-ras) oncogene homolog
S100A6 S100 calcium binding protein A6
S1PR1 sphingosine-1-phosphate receptor 1
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB3A1 secretoglobin, family 3A, member 1
SEMG1 semenogelin I
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGK1 serum/glucocorticoid regulated kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A9 solute carrier family 12, member 9
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SOD2 superoxide dismutase 2, mitochondrial
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF2 serine/arginine-rich splicing factor 2
SSTR4 somatostatin receptor 4
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STMN1 stathmin 1
TAS2R38 taste receptor, type 2, member 38
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TF transferrin
TFF1 trefoil factor 1
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THRSP thyroid hormone responsive
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TKT transketolase
TLE4 transducin-like enhancer of split 4
TLR4 toll-like receptor 4
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM37 transmembrane protein 37
TP53 tumor protein p53
TP53I3 tumor protein p53 inducible protein 3
TP63 tumor protein p63
TPM3 tropomyosin 3
TPT1 tumor protein, translationally-controlled 1
TRPS1 trichorhinophalangeal syndrome I
TSC22D1 TSC22 domain family, member 1
TSHR thyroid stimulating hormone receptor
TTF1 transcription termination factor, RNA polymerase I
TUBB2B tubulin, beta 2B class IIb
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
UBE2I ubiquitin-conjugating enzyme E2I
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
URI1 URI1, prefoldin-like chaperone
UVRAG UV radiation resistance associated
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VTN vitronectin
XDH xanthine dehydrogenase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB1 zinc finger E-box binding homeobox 1