Carcinosarcoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A mixed cell type cancer that has_material_basis_in carcinomatous (epithelial tissue) and sarcomatous (connective tissue) components. (Human Disease Ontology, DOID_4236)
External Link https://www.disgenet.org/browser/0/1/0/C0007140
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Genes

89 genes associated with the disease Carcinosarcoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ALK anaplastic lymphoma receptor tyrosine kinase
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT2 angiopoietin 2
AR androgen receptor
ATN1 atrophin 1
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
CD274 CD274 molecule
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CHP1 calcineurin-like EF-hand protein 1
CLDN3 claudin 3
CLDN4 claudin 4
CTAG1B cancer/testis antigen 1B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCDC2 doublecortin domain containing 2
DCTN3 dynactin 3 (p22)
DICER1 dicer 1, ribonuclease type III
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
F2R coagulation factor II (thrombin) receptor
FBN1 fibrillin 1
FGFR2 fibroblast growth factor receptor 2
FOXA2 forkhead box A2
GATA3 GATA binding protein 3
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HPS5 Hermansky-Pudlak syndrome 5
IFITM1 interferon induced transmembrane protein 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL2 interleukin 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
MAGEA4 melanoma antigen family A4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MSH2 mutS homolog 2
MYOG myogenin (myogenic factor 4)
NCAM1 neural cell adhesion molecule 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOX4 NADPH oxidase 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PAX8 paired box 8
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHB2 prohibitin 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTPA protein phosphatase 2 phosphatase activator
RACGAP1 Rac GTPase activating protein 1
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SATB2 SATB homeobox 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX9 SRY (sex determining region Y)-box 9
SYP synaptophysin
TACSTD2 tumor-associated calcium signal transducer 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TNF tumor necrosis factor
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TSHZ1 teashirt zinc finger homeobox 1
VEGFA vascular endothelial growth factor A
VIM vimentin
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZEB1 zinc finger E-box binding homeobox 1