Cardiac Arrest Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A congestive heart failure characterized by a sudden stop in effective blood circulation due to the failure of the heart to contract effectively or at all. (Human Disease Ontology, DOID_0060319)
External Link https://www.disgenet.org/browser/0/1/0/C0018790
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Genes

387 genes associated with the disease Cardiac Arrest in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACLY ATP citrate lyase
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTB actin, beta
ADCY6 adenylate cyclase 6
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADRB2 adrenoceptor beta 2, surface
AFG3L2 AFG3-like AAA ATPase 2
AGBL2 ATP/GTP binding protein-like 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIF1 allograft inflammatory factor 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKAP9 A kinase (PRKA) anchor protein 9
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALOX15 arachidonate 15-lipoxygenase
AMBP alpha-1-microglobulin/bikunin precursor
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL3 angiopoietin-like 3
ANGPTL4 angiopoietin-like 4
ANXA1 annexin A1
ANXA6 annexin A6
APOE apolipoprotein E
AQP4 aquaporin 4
AR androgen receptor
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARSA arylsulfatase A
ASCC1 activating signal cointegrator 1 complex subunit 1
ASIC1 acid sensing (proton gated) ion channel 1
ATN1 atrophin 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
ATXN10 ataxin 10
ATXN2 ataxin 2
ATXN3 ataxin 3
ATXN7 ataxin 7
AVPR1B arginine vasopressin receptor 1B
AVPR2 arginine vasopressin receptor 2
AZIN2 antizyme inhibitor 2
BAX BCL2-associated X protein
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BTBD8 BTB (POZ) domain containing 8
C20ORF194 chromosome 20 open reading frame 194
C5ORF42 chromosome 5 open reading frame 42
C9ORF72 chromosome 9 open reading frame 72
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALCR calcitonin receptor
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALR calreticulin
CAPN1 calpain 1, (mu/I) large subunit
CAPS calcyphosine
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CAT catalase
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDC7 cell division cycle 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEP85L centrosomal protein 85kDa-like
COX1
COX2
CRISP2 cysteine-rich secretory protein 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSTB cystatin B (stefin B)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DCTN6 dynactin 6
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DNM1L dynamin 1-like
DSP desmoplakin
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DYNLL1 dynein, light chain, LC8-type 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELANE elastase, neutrophil expressed
ELOVL4 ELOVL fatty acid elongase 4
ELOVL5 ELOVL fatty acid elongase 5
ENO2 enolase 2 (gamma, neuronal)
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBIN erbb2 interacting protein
ESR1 estrogen receptor 1
ETFA electron-transfer-flavoprotein, alpha polypeptide
F2R coagulation factor II (thrombin) receptor
F5 coagulation factor V (proaccelerin, labile factor)
FAN1 FANCD2/FANCI-associated nuclease 1
FBN1 fibrillin 1
FGF14 fibroblast growth factor 14
FGF2 fibroblast growth factor 2 (basic)
FPR1 formyl peptide receptor 1
FXN frataxin
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADL1 glutamate decarboxylase-like 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBA glucosidase, beta, acid
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GFAP glial fibrillary acidic protein
GPC5 glypican 5
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GRAP2 GRB2-related adaptor protein 2
GRK2 G protein-coupled receptor kinase 2
GSR glutathione reductase
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HBS1L HBS1-like translational GTPase
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HCRT hypocretin (orexin) neuropeptide precursor
HDAC2 histone deacetylase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMOX1 heme oxygenase 1
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFNG interferon, gamma
IFRD1 interferon-related developmental regulator 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL10 interleukin 10
IL11 interleukin 11
IL13 interleukin 13
IL17A interleukin 17A
IL17D interleukin 17D
IL18 interleukin 18
IL1B interleukin 1, beta
IL2 interleukin 2
IL27 interleukin 27
IL37 interleukin 37
IL4R interleukin 4 receptor
IL6 interleukin 6
IL7 interleukin 7
INS insulin
INSRR insulin receptor-related receptor
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLF1 Kruppel-like factor 1 (erythroid)
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMC2 laminin, gamma 2
LBR lamin B receptor
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LIPA lipase A, lysosomal acid, cholesterol esterase
LMNA lamin A/C
LOC102724560 cystathionine beta-synthase
LPCAT1 lysophosphatidylcholine acyltransferase 1
LTC4S leukotriene C4 synthase
LUC7L3 LUC7-like 3 (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MGLL monoglyceride lipase
MIPEP mitochondrial intermediate peptidase
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR11 myotubularin related protein 11
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MVP major vault protein
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBPC3 myosin binding protein C, cardiac
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYDGF myeloid-derived growth factor
NCAM1 neural cell adhesion molecule 1
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
NEFL neurofilament, light polypeptide
NEUROD1 neuronal differentiation 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NLK nemo-like kinase
NLRP3 NLR family, pyrin domain containing 3
NOP56 NOP56 ribonucleoprotein
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOX4 NADPH oxidase 4
NT5E 5'-nucleotidase, ecto (CD73)
OAT ornithine aminotransferase
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OSCAR osteoclast associated, immunoglobulin-like receptor
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX5 paired box 5
PDE4A phosphodiesterase 4A, cAMP-specific
PDYN prodynorphin
PGF placental growth factor
PGR progesterone receptor
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKP2 plakophilin 2
PLA2G15 phospholipase A2, group XV
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLAT plasminogen activator, tissue
PLB1 phospholipase B1
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLN phospholamban
PMCH pro-melanin-concentrating hormone
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLG polymerase (DNA directed), gamma
POMC proopiomelanocortin
POR P450 (cytochrome) oxidoreductase
PPA2 pyrophosphatase (inorganic) 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCG protein kinase C, gamma
PRSS55 protease, serine, 55
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPA protein phosphatase 2 phosphatase activator
PVR poliovirus receptor
RAN RAN, member RAS oncogene family
RANGRF RAN guanine nucleotide release factor
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBM45 RNA binding motif protein 45
REN renin
RETN resistin
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR2 ryanodine receptor 2 (cardiac)
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN2B sodium channel, voltage gated, type II beta subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCT secretin
SDC1 syndecan 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SGSM3 small G protein signaling modulator 3
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLITRK1 SLIT and NTRK-like family, member 1
SLMAP sarcolemma associated protein
SMN1 survival of motor neuron 1, telomeric
SOD1 superoxide dismutase 1, soluble
SPTBN2 spectrin, beta, non-erythrocytic 2
SPZ1 spermatogenic leucine zipper 1
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYN1 synapsin I
SYP synaptophysin
TANGO2 transport and golgi organization 2 homolog (Drosophila)
TBP TATA box binding protein
TBX19 T-box 19
TEK TEK tyrosine kinase, endothelial
TFRC transferrin receptor
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM6 transglutaminase 6
THBS1 thrombospondin 1
TICAM2 toll-like receptor adaptor molecule 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TPO thyroid peroxidase
TRDN triadin
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPYL1 TSPY-like 1
TTBK2 tau tubulin kinase 2
TTR transthyretin
TWNK twinkle mtDNA helicase
UBASH3B ubiquitin associated and SH3 domain containing B
UGCG UDP-glucose ceramide glucosyltransferase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VSX2 visual system homeobox 2
WWOX WW domain containing oxidoreductase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB2 zinc finger E-box binding homeobox 2