Cardiomyopathy Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).|A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive. (Experimental Factor Ontology, EFO_0000318)
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Genes

63 genes associated with the disease Cardiomyopathy in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 1.944
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.944
INPP5F inositol polyphosphate-5-phosphatase F 1.944
SPEN spen family transcriptional repressor 1.889
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 1.889
CLCNKA chloride channel, voltage-sensitive Ka 1.889
SRARP steroid receptor associated and regulated protein 1.889
CLCNKB chloride channel, voltage-sensitive Kb 1.889
ZBTB17 zinc finger and BTB domain containing 17 1.889
FAM131C family with sequence similarity 131, member C 1.889
VPREB3 pre-B lymphocyte 3 1.671
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 1.671
C22ORF15 chromosome 22 open reading frame 15 1.671
DERL3 derlin 3 1.671
ZNF70 zinc finger protein 70 1.671
MMP11 matrix metallopeptidase 11 1.671
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 1.671
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.671
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.671
TMEM43 transmembrane protein 43 1.617
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.617
XPC xeroderma pigmentosum, complementation group C 1.617
TTN titin 1.419
CCDC141 coiled-coil domain containing 141 1.419
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 1.419
CCDC136 coiled-coil domain containing 136 1.276
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 1.276
KCP kielin/chordin-like protein 1.276
CALU calumenin 1.276
IRF5 interferon regulatory factor 5 1.276
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.276
FLNC filamin C, gamma 1.276
NMB neuromedin B 1.237
ZSCAN2 zinc finger and SCAN domain containing 2 1.237
ZNF592 zinc finger protein 592 1.237
WDR73 WD repeat domain 73 1.237
SEC11A SEC11 homolog A (S. cerevisiae) 1.237
MIS12 MIS12 kinetochore complex component 1.078
WSCD1 WSC domain containing 1 1.078
NLRP1 NLR family, pyrin domain containing 1 1.078
SVIL supervillin 1.03
LYZL1 lysozyme-like 1 1.03
TPGS2 tubulin polyglutamylase complex subunit 2 0.97
FHOD3 formin homology 2 domain containing 3 0.97
MOCOS molybdenum cofactor sulfurase 0.97
KIAA1328 KIAA1328 0.97
PRKCA protein kinase C, alpha 0.959
APOH apolipoprotein H (beta-2-glycoprotein I) 0.959
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.929
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.929
ARL5A ADP-ribosylation factor-like 5A 0.929
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.819
RAB44 RAB44, member RAS oncogene family 0.702
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.702
SRSF3 serine/arginine-rich splicing factor 3 0.702
CPNE5 copine V 0.702
CFAP44 cilia and flagella associated protein 44 0.563
BOC BOC cell adhesion associated, oncogene regulated 0.563
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.556
CTSB cathepsin B 0.556
DEFB136 defensin, beta 136 0.556
DEFB135 defensin, beta 135 0.556
DEFB134 defensin, beta 134 0.556