Cardiomyopathy_Myocardial tissue_GSE1869 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1869
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Genes

600 genes differentially expressed during Cardiomyopathy_Myocardial tissue_GSE1869 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ZNF674 zinc finger protein 674 3.38613
MIS18BP1 MIS18 binding protein 1 2.99225
NF1 neurofibromin 1 2.98763
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2 2.9123
ZBTB3 zinc finger and BTB domain containing 3 2.8864
FGFR1OP FGFR1 oncogene partner 2.87355
EMC1 ER membrane protein complex subunit 1 2.77922
GPR85 G protein-coupled receptor 85 2.76767
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 2.73847
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.64763
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.577
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.5489
PKD2L2 polycystic kidney disease 2-like 2 2.54796
VN1R1 vomeronasal 1 receptor 1 2.54753
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.53082
BBS4 Bardet-Biedl syndrome 4 2.4061
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 2.40088
SIN3B SIN3 transcription regulator family member B 2.362
EEF1G eukaryotic translation elongation factor 1 gamma 2.34698
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2.31707
GPM6A glycoprotein M6A 2.28268
IGFBP1 insulin-like growth factor binding protein 1 2.28184
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.27528
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.26046
AMELX amelogenin, X-linked 2.19947
SCG3 secretogranin III 2.19515
TBC1D22A TBC1 domain family, member 22A 2.18545
KIAA1107 KIAA1107 2.16585
CENPF centromere protein F, 350/400kDa 2.15108
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.14771
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 2.144
SCN1A sodium channel, voltage gated, type I alpha subunit 2.13357
FAM149B1 family with sequence similarity 149, member B1 2.12718
ZNF471 zinc finger protein 471 2.10916
MED12 mediator complex subunit 12 2.10831
PNMA2 paraneoplastic Ma antigen 2 2.10742
EIF5A2 eukaryotic translation initiation factor 5A2 2.10379
ZNF81 zinc finger protein 81 2.09044
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 2.08944
MGC4859 uncharacterized LOC79150 2.08558
TOM1L2 target of myb1-like 2 (chicken) 2.08385
CCDC121 coiled-coil domain containing 121 2.05413
CDC5L cell division cycle 5-like 2.05147
ADRBK2 adrenergic, beta, receptor kinase 2 2.04694
GPC3 glypican 3 2.0399
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.03074
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 2.02615
ZNF493 zinc finger protein 493 2.02031
AUTS2 autism susceptibility candidate 2 2.01868
HIBADH 3-hydroxyisobutyrate dehydrogenase 2.01494
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene 1.99863
MMP1 matrix metallopeptidase 1 1.99036
RPS14 ribosomal protein S14 1.98419
MRPS11 mitochondrial ribosomal protein S11 1.96836
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 1.96714
STK38 serine/threonine kinase 38 1.94745
MCOLN3 mucolipin 3 1.94679
LMNB1 lamin B1 1.94568
KDM4D lysine (K)-specific demethylase 4D 1.94475
ZNF639 zinc finger protein 639 1.94193
RREB1 ras responsive element binding protein 1 1.93939
ZNF234 zinc finger protein 234 1.92816
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1.92009
FAM76A family with sequence similarity 76, member A 1.91624
IRGQ immunity-related GTPase family, Q 1.91367
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 1.91231
MFSD9 major facilitator superfamily domain containing 9 1.90744
MSX2 msh homeobox 2 1.90317
MAGEB1 melanoma antigen family B1 1.88969
ARHGAP1 Rho GTPase activating protein 1 1.88847
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.88735
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 1.8795
RPL17 ribosomal protein L17 1.87336
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.87253
COX5AP1 cytochrome c oxidase subunit Va pseudogene 1 1.86973
RPL18 ribosomal protein L18 1.86933
LGTN ligatin 1.86611
HIST1H2AG histone cluster 1, H2ag 1.86269
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.85286
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.85277
ARL14 ADP-ribosylation factor-like 14 1.8488
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 1.84511
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.84121
HEXA-AS1 HEXA antisense RNA 1 1.83671
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 1.82872
CXORF57 chromosome X open reading frame 57 1.82677
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.82592
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 1.8227
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.81353
KIAA1033 KIAA1033 1.81052
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1.7964
HMGN2 high mobility group nucleosomal binding domain 2 1.79093
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 1.7908
FLJ10038 uncharacterized protein FLJ10038 1.7893
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) 1.78768
IL1A interleukin 1, alpha 1.7829
SPO11 SPO11 meiotic protein covalently bound to DSB 1.77971
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 1.77919
NOL12 nucleolar protein 12 1.77709
RPL35A ribosomal protein L35a 1.77279
EFCAB11 EF-hand calcium binding domain 11 1.77121
WNT9A wingless-type MMTV integration site family, member 9A 1.76623
ZNF334 zinc finger protein 334 1.7618
NEUROD1 neuronal differentiation 1 1.75252
AIP aryl hydrocarbon receptor interacting protein 1.74375
ZNF33B zinc finger protein 33B 1.74253
LYPLA2 lysophospholipase II 1.73843
F2RL3 coagulation factor II (thrombin) receptor-like 3 1.72965
ACSL6 acyl-CoA synthetase long-chain family member 6 1.72943
WNT5A wingless-type MMTV integration site family, member 5A 1.72883
EMX2 empty spiracles homeobox 2 1.72853
CDK1 cyclin-dependent kinase 1 1.72429
C1ORF50 chromosome 1 open reading frame 50 1.71814
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.71673
MED18 mediator complex subunit 18 1.71355
NEK1 NIMA-related kinase 1 1.70999
COPZ2 coatomer protein complex, subunit zeta 2 1.70659
ZNF350 zinc finger protein 350 1.70552
ZNF813 zinc finger protein 813 1.70394
MAGOHB mago-nashi homolog B (Drosophila) 1.69992
SPATA6 spermatogenesis associated 6 1.69733
RPS28 ribosomal protein S28 1.69634
KCNK13 potassium channel, two pore domain subfamily K, member 13 1.69618
CLCA3P chloride channel accessory 3, pseudogene 1.69451
ZNF133 zinc finger protein 133 1.69372
STEAP1 six transmembrane epithelial antigen of the prostate 1 1.692
HBP1 HMG-box transcription factor 1 1.69116
FAM135A family with sequence similarity 135, member A 1.68468
THSD4 thrombospondin, type I, domain containing 4 1.68359
USP22 ubiquitin specific peptidase 22 1.68342
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.68169
PDZK1 PDZ domain containing 1 1.67144
MAP2K5 mitogen-activated protein kinase kinase 5 1.66644
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 1.66597
PLA2G4B phospholipase A2, group IVB (cytosolic) 1.6626
ERV3-2 endogenous retrovirus group 3, member 2 1.64866
UROD uroporphyrinogen decarboxylase 1.6461
EEA1 early endosome antigen 1 1.64222
AKR1D1 aldo-keto reductase family 1, member D1 1.64036
TRMT5 tRNA methyltransferase 5 1.63618
STX6 syntaxin 6 1.63503
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 1.61973
TAC1 tachykinin, precursor 1 1.61825
NFRKB nuclear factor related to kappaB binding protein 1.61346
EFNA1 ephrin-A1 1.611
HBD hemoglobin, delta 1.61009
SPTBN1 spectrin, beta, non-erythrocytic 1 1.60863
TRIP6 thyroid hormone receptor interactor 6 1.60714
IDS iduronate 2-sulfatase 1.60598
CNOT4 CCR4-NOT transcription complex, subunit 4 1.60488
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 1.60271
BRIP1 BRCA1 interacting protein C-terminal helicase 1 1.60269
FZD10 frizzled class receptor 10 1.6022
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.60087
SHISA6 shisa family member 6 1.60061
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 1.59027
ZFYVE26 zinc finger, FYVE domain containing 26 1.58782
LDAH lipid droplet associated hydrolase 1.58539
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.58489
RPL15 ribosomal protein L15 1.5775
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.57635
ETAA1 Ewing tumor-associated antigen 1 1.57169
NFYA nuclear transcription factor Y, alpha 1.57008
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1.57004
SVIL supervillin 1.56842
IL20RA interleukin 20 receptor, alpha 1.56808
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 1.56619
RPL9 ribosomal protein L9 1.56539
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.55951
AKAP7 A kinase (PRKA) anchor protein 7 1.55736
NFE2 nuclear factor, erythroid 2 1.5573
TTC23 tetratricopeptide repeat domain 23 1.55719
RPL22P22 ribosomal protein L22 pseudogene 22 1.55416
COPS7B COP9 signalosome subunit 7B 1.55388
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.55342
DPY19L1P1 DPY19L1 pseudogene 1 1.55227
PRMT2 protein arginine methyltransferase 2 1.55021
UBC ubiquitin C 1.55003
EPRS glutamyl-prolyl-tRNA synthetase 1.54294
HBBP1 hemoglobin, beta pseudogene 1 1.54255
C1ORF112 chromosome 1 open reading frame 112 1.542
PRDM2 PR domain containing 2, with ZNF domain 1.5417
TWISTNB TWIST neighbor 1.54067
SPATA20 spermatogenesis associated 20 1.53972
IL12B interleukin 12B 1.53658
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 1.53063
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.52894
IL26 interleukin 26 1.52811
UMPS uridine monophosphate synthetase 1.52376
TRIM33 tripartite motif containing 33 1.52216
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.51838
DIAPH3 diaphanous-related formin 3 1.51721
PDZRN4 PDZ domain containing ring finger 4 1.51688
SOX5 SRY (sex determining region Y)-box 5 1.51427
ATXN3 ataxin 3 1.51391
TFB1M transcription factor B1, mitochondrial 1.51195
ZNF510 zinc finger protein 510 1.50531
PFDN4 prefoldin subunit 4 1.50294
FAM162A family with sequence similarity 162, member A 1.49507
TCEA2 transcription elongation factor A (SII), 2 1.49049
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 1.48951
VCP valosin containing protein 1.48774
MAB21L1 mab-21-like 1 (C. elegans) 1.48733
ST20 suppressor of tumorigenicity 20 1.48722
LMAN2L lectin, mannose-binding 2-like 1.48586
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 1.48341
CLDN18 claudin 18 1.48333
PREP prolyl endopeptidase 1.48314
BRDT bromodomain, testis-specific 1.48276
SECISBP2 SECIS binding protein 2 1.48099
LTBP4 latent transforming growth factor beta binding protein 4 1.48011
TRIM9 tripartite motif containing 9 1.47894
UBB ubiquitin B 1.47824
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 1.47737
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 1.47704
AMT aminomethyltransferase 1.47686
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 1.47326
KIF25 kinesin family member 25 1.47218
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.47188
PFDN1 prefoldin subunit 1 1.46997
TMPRSS3 transmembrane protease, serine 3 1.4693
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.46345
TULP3 tubby like protein 3 1.4619
NPAT nuclear protein, ataxia-telangiectasia locus 1.45968
ZNF208 zinc finger protein 208 1.45861
GRN granulin 1.45161
IQCH IQ motif containing H 1.45101
CRELD1 cysteine-rich with EGF-like domains 1 1.44833
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 1.44569
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 1.44378
SORD sorbitol dehydrogenase 1.44321
CD4 CD4 molecule 1.44318
ADAM18 ADAM metallopeptidase domain 18 1.4417
ATRN attractin 1.43741
OR7E2P olfactory receptor, family 7, subfamily E, member 2 pseudogene 1.43734
MCM4 minichromosome maintenance complex component 4 1.43559
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 1.43546
KANK1 KN motif and ankyrin repeat domains 1 1.43182
KIF20B kinesin family member 20B 1.42954
MTNR1A melatonin receptor 1A 1.42941
PTPRM protein tyrosine phosphatase, receptor type, M 1.42774
ZNF528 zinc finger protein 528 1.42534
MORC1 MORC family CW-type zinc finger 1 1.42334
KIF23 kinesin family member 23 1.42161
EIF4A2 eukaryotic translation initiation factor 4A2 1.42116
LRP2BP LRP2 binding protein 1.41971
ZNF586 zinc finger protein 586 1.41877
PSAT1 phosphoserine aminotransferase 1 1.41651
TOM1L1 target of myb1 (chicken)-like 1 1.41541
SMIM2 small integral membrane protein 2 1.4144
DST dystonin 1.41191
LAMA2 laminin, alpha 2 1.41092
PBK PDZ binding kinase 1.4097
MKRN2 makorin ring finger protein 2 1.40805
RNF17 ring finger protein 17 1.40596
PML promyelocytic leukemia 1.40402
MAN2B2 mannosidase, alpha, class 2B, member 2 1.40251
ZNF354A zinc finger protein 354A 1.3993
DGCR8 DGCR8 microprocessor complex subunit 1.39888
DEFA5 defensin, alpha 5, Paneth cell-specific 1.39652
SIRT3 sirtuin 3 1.39352
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 1.39344
YIPF4 Yip1 domain family, member 4 1.39107
ZNF24 zinc finger protein 24 1.38947
INSL5 insulin-like 5 1.3888
NARFL nuclear prelamin A recognition factor-like 1.38688
IK IK cytokine, down-regulator of HLA II 1.38664
B3GAT1 beta-1,3-glucuronyltransferase 1 1.38176
LYRM9 LYR motif containing 9 1.38166
C14ORF28 chromosome 14 open reading frame 28 1.37596
NPHP4 nephronophthisis 4 1.37488
PIWIL1 piwi-like RNA-mediated gene silencing 1 1.36947
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 1.3656
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.36233
STON1 stonin 1 1.35982
SORBS1 sorbin and SH3 domain containing 1 1.35615
LINC00115 long intergenic non-protein coding RNA 115 1.35524
XPO1 exportin 1 1.35336
IKZF5 IKAROS family zinc finger 5 (Pegasus) 1.35076
FAM188A family with sequence similarity 188, member A 1.34959
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 1.34931
CASC1 cancer susceptibility candidate 1 1.34858
ZNF750 zinc finger protein 750 1.34763
PLAUR plasminogen activator, urokinase receptor 1.34692
CRYM crystallin, mu 1.34445
BRWD1 bromodomain and WD repeat domain containing 1 1.34288
TRPC7 transient receptor potential cation channel, subfamily C, member 7 1.34146
TRAK1 trafficking protein, kinesin binding 1 1.34002
REPS1 RALBP1 associated Eps domain containing 1 1.33959
PLK5 polo-like kinase 5 1.33827
TPR translocated promoter region, nuclear basket protein 1.3374
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.33703
PRR14L proline rich 14-like 1.33641
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 1.33196
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.33123
RNGTT RNA guanylyltransferase and 5'-phosphatase 1.32823
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 1.32697
AFF1 AF4/FMR2 family, member 1 1.32641
LPIN1 lipin 1 1.32615
PCDHA2 protocadherin alpha 2 1.32613

decreased expression

Symbol Name Standardized Value
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.83149
PRIM2 primase, DNA, polypeptide 2 (58kDa) -2.81266
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2 -2.79376
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene -2.77983
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.74194
SOX3 SRY (sex determining region Y)-box 3 -2.73064
PPP4R2 protein phosphatase 4, regulatory subunit 2 -2.69789
ZFP37 ZFP37 zinc finger protein -2.68387
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.6838
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 -2.63871
KLRC4 killer cell lectin-like receptor subfamily C, member 4 -2.59429
TEX12 testis expressed 12 -2.58157
SOX30 SRY (sex determining region Y)-box 30 -2.57848
ZNF236 zinc finger protein 236 -2.51595
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.48417
HDGF hepatoma-derived growth factor -2.47823
SLC16A4 solute carrier family 16, member 4 -2.47016
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -2.4626
SPC25 SPC25, NDC80 kinetochore complex component -2.45047
TIGD6 tigger transposable element derived 6 -2.44437
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 -2.44097
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -2.43573
TMX4 thioredoxin-related transmembrane protein 4 -2.43176
SLC35F5 solute carrier family 35, member F5 -2.41502
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -2.41252
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -2.40435
ZNF318 zinc finger protein 318 -2.39987
RCAN3 RCAN family member 3 -2.39842
OSR2 odd-skipped related transciption factor 2 -2.38999
MAGEA6 melanoma antigen family A6 -2.37108
KIAA0087 KIAA0087 -2.34846
TMPRSS11E transmembrane protease, serine 11E -2.30678
MFAP3 microfibrillar-associated protein 3 -2.30481
KIF18A kinesin family member 18A -2.29055
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -2.28548
INHBC inhibin, beta C -2.27943
CEP290 centrosomal protein 290kDa -2.27772
PHF14 PHD finger protein 14 -2.25547
ACOXL acyl-CoA oxidase-like -2.23429
ADCY9 adenylate cyclase 9 -2.21037
SYNGR3 synaptogyrin 3 -2.20909
SPTA1 spectrin, alpha, erythrocytic 1 -2.20505
SALL1 spalt-like transcription factor 1 -2.19599
PLSCR3 phospholipid scramblase 3 -2.17984
TNP2 transition protein 2 (during histone to protamine replacement) -2.17689
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) -2.15789
SLC25A44 solute carrier family 25, member 44 -2.15438
RPGRIP1L RPGRIP1-like -2.15353
ATF4 activating transcription factor 4 -2.15189
KCNK15 potassium channel, two pore domain subfamily K, member 15 -2.15031
SREBF1 sterol regulatory element binding transcription factor 1 -2.13723
TMEM53 transmembrane protein 53 -2.13428
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -2.13351
STYK1 serine/threonine/tyrosine kinase 1 -2.12919
CA10 carbonic anhydrase X -2.11657
TMEM144 transmembrane protein 144 -2.11388
FANCI Fanconi anemia, complementation group I -2.11366
NCAPG non-SMC condensin I complex, subunit G -2.11103
LRP1B low density lipoprotein receptor-related protein 1B -2.1089
FAM89B family with sequence similarity 89, member B -2.10872
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.10732
TMEM11 transmembrane protein 11 -2.10365
THAP9 THAP domain containing 9 -2.09824
KLHL23 kelch-like family member 23 -2.09591
TATDN2 TatD DNase domain containing 2 -2.09478
MATN3 matrilin 3 -2.09294
RAB6B RAB6B, member RAS oncogene family -2.08949
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -2.0808
TEX14 testis expressed 14 -2.07194
RNFT1 ring finger protein, transmembrane 1 -2.0682
PTK6 protein tyrosine kinase 6 -2.0614
MAN1A2 mannosidase, alpha, class 1A, member 2 -2.04471
SBSPON somatomedin B and thrombospondin, type 1 domain containing -2.04445
SH3BP2 SH3-domain binding protein 2 -2.03897
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -2.03529
CDR1 cerebellar degeneration-related protein 1, 34kDa -2.03027
C9ORF40 chromosome 9 open reading frame 40 -2.02876
PARD3 par-3 family cell polarity regulator -2.02739
GNAS GNAS complex locus -2.02263
PALLD palladin, cytoskeletal associated protein -2.02236
PCDH11Y protocadherin 11 Y-linked -2.01598
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.01372
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -2.00853
DEDD death effector domain containing -2.00205
SLC10A3 solute carrier family 10, member 3 -1.99324
SNX11 sorting nexin 11 -1.98699
SPATS2L spermatogenesis associated, serine-rich 2-like -1.98534
TOP2A topoisomerase (DNA) II alpha 170kDa -1.97716
RAB11FIP5 RAB11 family interacting protein 5 (class I) -1.97665
MSMB microseminoprotein, beta- -1.97506
PCNAP3 proliferating cell nuclear antigen pseudogene 3 -1.97136
HPS1 Hermansky-Pudlak syndrome 1 -1.96973
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -1.96668
ZNF225 zinc finger protein 225 -1.96417
BTF3P11 basic transcription factor 3 pseudogene 11 -1.95809
DEFB126 defensin, beta 126 -1.95382
SUN2 Sad1 and UNC84 domain containing 2 -1.95371
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -1.94176
GPS2 G protein pathway suppressor 2 -1.93909
C7ORF33 chromosome 7 open reading frame 33 -1.92682
TMOD2 tropomodulin 2 (neuronal) -1.91958
PAWR PRKC, apoptosis, WT1, regulator -1.91856
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -1.91499
STX2 syntaxin 2 -1.91356
INVS inversin -1.90592
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -1.9043
CSNK1G2 casein kinase 1, gamma 2 -1.90199
ZNF516 zinc finger protein 516 -1.90135
FZD5 frizzled class receptor 5 -1.90013
ZHX3 zinc fingers and homeoboxes 3 -1.89522
RIPK2 receptor-interacting serine-threonine kinase 2 -1.89441
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.89394
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -1.89356
POPDC2 popeye domain containing 2 -1.89296
SCN9A sodium channel, voltage gated, type IX alpha subunit -1.88193
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -1.88043
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -1.87809
RABIF RAB interacting factor -1.87005
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -1.86822
ZNF576 zinc finger protein 576 -1.86787
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -1.86719
TEAD3 TEA domain family member 3 -1.86683
HMG20B high mobility group 20B -1.86352
CCDC88A coiled-coil domain containing 88A -1.86258
SAP30L SAP30-like -1.85805
PTRH2 peptidyl-tRNA hydrolase 2 -1.8564
ERCC6L excision repair cross-complementation group 6-like -1.85559
ZNF80 zinc finger protein 80 -1.85014
DYM dymeclin -1.84856
PROCR protein C receptor, endothelial -1.83668
TRGV7 T cell receptor gamma variable 7 (pseudogene) -1.83261
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -1.83019
THNSL1 threonine synthase-like 1 (S. cerevisiae) -1.82762
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -1.82741
C19ORF26 chromosome 19 open reading frame 26 -1.81783
ARNT aryl hydrocarbon receptor nuclear translocator -1.80185
STARD7 StAR-related lipid transfer (START) domain containing 7 -1.80173
FBXW4 F-box and WD repeat domain containing 4 -1.79812
GRIA4 glutamate receptor, ionotropic, AMPA 4 -1.79655
CA5BP1 carbonic anhydrase VB pseudogene 1 -1.79256
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 -1.7731
WDR55 WD repeat domain 55 -1.77279
PAPD7 PAP associated domain containing 7 -1.77069
SS18 synovial sarcoma translocation, chromosome 18 -1.76493
NPM3 nucleophosmin/nucleoplasmin 3 -1.76371
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.76192
EEF1DP5 eukaryotic translation elongation factor 1 delta pseudogene 5 -1.76073
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 -1.75293
RING1 ring finger protein 1 -1.75083
CASKIN2 CASK interacting protein 2 -1.74976
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -1.74627
MON1B MON1 secretory trafficking family member B -1.74272
UNC93A unc-93 homolog A (C. elegans) -1.74267
AGFG1 ArfGAP with FG repeats 1 -1.74247
TBC1D13 TBC1 domain family, member 13 -1.73827
EMC9 ER membrane protein complex subunit 9 -1.737
STRADA STE20-related kinase adaptor alpha -1.73636
XYLB xylulokinase homolog (H. influenzae) -1.73464
TUBAL3 tubulin, alpha-like 3 -1.73443
KLC2 kinesin light chain 2 -1.73035
HCFC2 host cell factor C2 -1.72904
ZFP64 ZFP64 zinc finger protein -1.72783
SLC25A51 solute carrier family 25, member 51 -1.72744
OR7E19P olfactory receptor, family 7, subfamily E, member 19 pseudogene -1.72409
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -1.72027
NAV3 neuron navigator 3 -1.71932
FAM49B family with sequence similarity 49, member B -1.71781
GTPBP3 GTP binding protein 3 (mitochondrial) -1.71305
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -1.71185
PTH1R parathyroid hormone 1 receptor -1.70942
GAP43 growth associated protein 43 -1.70643
GMDS GDP-mannose 4,6-dehydratase -1.70234
MAX MYC associated factor X -1.69849
EP400 E1A binding protein p400 -1.69679
GLRX3 glutaredoxin 3 -1.69594
CPPED1 calcineurin-like phosphoesterase domain containing 1 -1.6953
CHM choroideremia (Rab escort protein 1) -1.69389
MRPL48 mitochondrial ribosomal protein L48 -1.69314
SLC17A2 solute carrier family 17, member 2 -1.69301
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -1.69128
MAP2K1 mitogen-activated protein kinase kinase 1 -1.68969
PPARG peroxisome proliferator-activated receptor gamma -1.68556
AQR aquarius intron-binding spliceosomal factor -1.68327
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.67816
RFX5 regulatory factor X, 5 (influences HLA class II expression) -1.67813
MYF6 myogenic factor 6 (herculin) -1.67672
MYLK3 myosin light chain kinase 3 -1.67621
FAM65A family with sequence similarity 65, member A -1.67332
LRRC8B leucine rich repeat containing 8 family, member B -1.66754
EDIL3 EGF-like repeats and discoidin I-like domains 3 -1.66466
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -1.66063
RBP1 retinol binding protein 1, cellular -1.65989
CYB561 cytochrome b561 -1.65936
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -1.65841
NREP neuronal regeneration related protein -1.65631
FCF1 FCF1 rRNA-processing protein -1.64825
ITPK1 inositol-tetrakisphosphate 1-kinase -1.64752
CFL1 cofilin 1 (non-muscle) -1.64627
SUSD5 sushi domain containing 5 -1.64569
EXOC3 exocyst complex component 3 -1.64307
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -1.64008
BBS7 Bardet-Biedl syndrome 7 -1.62868
FAM120A family with sequence similarity 120A -1.62572
MED22 mediator complex subunit 22 -1.62231
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -1.61641
PUF60 poly-U binding splicing factor 60KDa -1.61071
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -1.60816
AHNAK2 AHNAK nucleoprotein 2 -1.60755
SELE selectin E -1.60704
C16ORF58 chromosome 16 open reading frame 58 -1.60625
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -1.6049
ELOVL2 ELOVL fatty acid elongase 2 -1.60382
IL13RA2 interleukin 13 receptor, alpha 2 -1.59913
PRC1 protein regulator of cytokinesis 1 -1.59871
HAVCR1 hepatitis A virus cellular receptor 1 -1.59824
HOXB5 homeobox B5 -1.5971
FAM69A family with sequence similarity 69, member A -1.59669
MSH4 mutS homolog 4 -1.59473
FLII flightless I homolog (Drosophila) -1.59345
JAG2 jagged 2 -1.59337
VIP vasoactive intestinal peptide -1.58877
UNKL unkempt family zinc finger-like -1.58572
RBM48 RNA binding motif protein 48 -1.58529
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) -1.58384
MCOLN1 mucolipin 1 -1.58247
SOD2 superoxide dismutase 2, mitochondrial -1.58237
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.58079
ST7 suppression of tumorigenicity 7 -1.5782
AASS aminoadipate-semialdehyde synthase -1.5776
GOSR2 golgi SNAP receptor complex member 2 -1.57716
UTS2 urotensin 2 -1.5741
CDYL chromodomain protein, Y-like -1.57345
PEMT phosphatidylethanolamine N-methyltransferase -1.57285
TTC30A tetratricopeptide repeat domain 30A -1.57105
PCBP1 poly(rC) binding protein 1 -1.56671
VIPR2 vasoactive intestinal peptide receptor 2 -1.56486
SEC24D SEC24 family member D -1.56481
COMMD1 copper metabolism (Murr1) domain containing 1 -1.5636
TBRG4 transforming growth factor beta regulator 4 -1.5614
MDM4 MDM4, p53 regulator -1.56136
DHRS7 dehydrogenase/reductase (SDR family) member 7 -1.56109
ADGRG1 adhesion G protein-coupled receptor G1 -1.56003
SEPT4 septin 4 -1.55633
LARGE like-glycosyltransferase -1.55572
NUP93 nucleoporin 93kDa -1.55542
MILR1 mast cell immunoglobulin-like receptor 1 -1.55476
PRKG2 protein kinase, cGMP-dependent, type II -1.55178
STK16 serine/threonine kinase 16 -1.546
MOCOS molybdenum cofactor sulfurase -1.5444
C14ORF105 chromosome 14 open reading frame 105 -1.54279
FJX1 four jointed box 1 (Drosophila) -1.5412
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -1.54107
ADGRL1 adhesion G protein-coupled receptor L1 -1.53947
WRNIP1 Werner helicase interacting protein 1 -1.52971
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -1.52403
SLC43A3 solute carrier family 43, member 3 -1.52323
TEX2 testis expressed 2 -1.52025
ZNF512B zinc finger protein 512B -1.51944
CLSTN2 calsyntenin 2 -1.51778
UBL4A ubiquitin-like 4A -1.51752
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -1.51645
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -1.50971
MYB v-myb avian myeloblastosis viral oncogene homolog -1.50814
C7ORF26 chromosome 7 open reading frame 26 -1.50778
SRF serum response factor (c-fos serum response element-binding transcription factor) -1.50487
HIST1H2BC histone cluster 1, H2bc -1.50481
NCKAP1 NCK-associated protein 1 -1.49854
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -1.49658
CDCA4 cell division cycle associated 4 -1.49645
MAPK7 mitogen-activated protein kinase 7 -1.49343
ZNF749 zinc finger protein 749 -1.49329
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -1.49247
GSTM4 glutathione S-transferase mu 4 -1.49231
PLXNB1 plexin B1 -1.49164
KLRC2 killer cell lectin-like receptor subfamily C, member 2 -1.4871
AFAP1 actin filament associated protein 1 -1.48065
DLG3 discs, large homolog 3 (Drosophila) -1.47992
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.47987
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -1.47782
CSNK2B casein kinase 2, beta polypeptide -1.47442
CD40 CD40 molecule, TNF receptor superfamily member 5 -1.47168
AP3B2 adaptor-related protein complex 3, beta 2 subunit -1.46791
PKM pyruvate kinase, muscle -1.466
MYEF2 myelin expression factor 2 -1.46519
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -1.46477
C14ORF93 chromosome 14 open reading frame 93 -1.46167
PTGER3 prostaglandin E receptor 3 (subtype EP3) -1.45784
C1ORF216 chromosome 1 open reading frame 216 -1.4567
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -1.45607
DND1 DND microRNA-mediated repression inhibitor 1 -1.45519
MBD1 methyl-CpG binding domain protein 1 -1.45329
IRX4 iroquois homeobox 4 -1.44902
FAM168B family with sequence similarity 168, member B -1.44682
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -1.4457
IL6R interleukin 6 receptor -1.44475
MBD2 methyl-CpG binding domain protein 2 -1.44448
LOC100505534 uncharacterized LOC100505534 -1.44353
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 -1.44135
SPINK1 serine peptidase inhibitor, Kazal type 1 -1.44013
MSX1 msh homeobox 1 -1.43831
Funding