Cardiotoxicity Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D066126
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Genes

58 genes/proteins associated with the disease Cardiotoxicity from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CBR1 carbonyl reductase 1 1.30819
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.2861
CHEK2 checkpoint kinase 2 1.25588
ATM ATM serine/threonine kinase 1.2368
CAT catalase 1.22821
GSR glutathione reductase 1.22339
BAX BCL2-associated X protein 1.22209
MAPK8 mitogen-activated protein kinase 8 1.22209
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.21402
GLO1 glyoxalase I 1.20751
NOX1 NADPH oxidase 1 1.19868
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.19014
H2AFX H2A histone family, member X 1.18981
BCL2 B-cell CLL/lymphoma 2 1.18948
MAP2K3 mitogen-activated protein kinase kinase 3 1.18326
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.17034
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.166
TGFB1 transforming growth factor, beta 1 1.15933
MAPK9 mitogen-activated protein kinase 9 1.15492
MAPK14 mitogen-activated protein kinase 14 1.142
MAP2K6 mitogen-activated protein kinase kinase 6 1.12872
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.12048
SPP1 secreted phosphoprotein 1 1.11501
TIMP1 TIMP metallopeptidase inhibitor 1 1.11431
BIRC5 baculoviral IAP repeat containing 5 1.11046
NOX4 NADPH oxidase 4 1.10562
GPX4 glutathione peroxidase 4 1.09892
COL1A1 collagen, type I, alpha 1 1.09366
FLT1 fms-related tyrosine kinase 1 1.09297
PDIA3 protein disulfide isomerase family A, member 3 1.09262
AQP3 aquaporin 3 (Gill blood group) 1.09154
MIR200C microRNA 200c 1.08868
PCNA proliferating cell nuclear antigen 1.08055
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.07022
MET MET proto-oncogene, receptor tyrosine kinase 1.06661
BBC3 BCL2 binding component 3 1.06515
CYBB cytochrome b-245, beta polypeptide 1.06333
FTH1 ferritin, heavy polypeptide 1 1.05936
CCNG1 cyclin G1 1.05936
KEAP1 kelch-like ECH-associated protein 1 1.05864
DDIT3 DNA-damage-inducible transcript 3 1.05685
IRS1 insulin receptor substrate 1 1.05423
CCND3 cyclin D3 1.052
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.04868
NOS2 nitric oxide synthase 2, inducible 1.04868
NOS3 nitric oxide synthase 3 (endothelial cell) 1.04721
SP7 Sp7 transcription factor 1.04427
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.03827
CCND2 cyclin D2 1.03604
MGMT O-6-methylguanine-DNA methyltransferase 1.03308
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.02671
CD14 CD14 molecule 1.02671
CD44 CD44 molecule (Indian blood group) 1.02559
CTSD cathepsin D 1.02151
COL1A2 collagen, type I, alpha 2 1.01852
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.01814
PLAU plasminogen activator, urokinase 1.01324
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.01249