Carvedilol Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure. (Chemical Entities of Biological Interest Ontology, CHEBI_3441)
External Link http://www.drugbank.ca/drugs/DB01136
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Genes

20 interacting proteins for the Carvedilol drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
GJA1 gap junction protein, alpha 1, 43kDa
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NPPB natriuretic peptide B
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SELE selectin E
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
XDH xanthine dehydrogenase