Caspase activation via extrinsic apoptotic signalling pathway Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5357769
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Genes

26 proteins participating in the Caspase activation via extrinsic apoptotic signalling pathway pathway from the Reactome Pathways 2024 dataset.

Symbol Name
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD14 CD14 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DCC DCC netrin 1 receptor
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
LY96 lymphocyte antigen 96
MAGED1 melanoma antigen family D1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TLR4 toll-like receptor 4
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
UNC5A unc-5 homolog A (C. elegans)
UNC5B unc-5 homolog B (C. elegans)