Catabolism of skeletal muscle in cachexia Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP5474.html
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Genes

40 proteins participating in the Catabolism of skeletal muscle in cachexia pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHUK conserved helix-loop-helix ubiquitous kinase
EP300 E1A binding protein p300
FBXO32 F-box protein 32
FOXO3 forkhead box O3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL6 interleukin 6
IL6R interleukin 6 receptor
JAK1 Janus kinase 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAPK11 mitogen-activated protein kinase 11
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MSTN myostatin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDK1 pyruvate dehydrogenase kinase, isozyme 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPTOR regulatory associated protein of MTOR, complex 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase