Catatonia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D002389
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Genes

215 genes/proteins associated with the disease Catatonia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CHRM4 cholinergic receptor, muscarinic 4 2.88009
PRL prolactin 2.42898
DRD2 dopamine receptor D2 2.40967
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.3903
BDNF brain-derived neurotrophic factor 2.33371
TH tyrosine hydroxylase 2.27646
FOS FBJ murine osteosarcoma viral oncogene homolog 2.25156
MAPK1 mitogen-activated protein kinase 1 2.19985
CAT catalase 2.19776
TNF tumor necrosis factor 2.1973
DRD1 dopamine receptor D1 2.17766
POMC proopiomelanocortin 2.15588
BAX BCL2-associated X protein 2.15568
MAPK3 mitogen-activated protein kinase 3 2.14296
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.11576
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.1108
PENK proenkephalin 2.10763
GSK3B glycogen synthase kinase 3 beta 2.09997
BCL2 B-cell CLL/lymphoma 2 2.07224
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.0124
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.96994
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.92091
TAC1 tachykinin, precursor 1 1.88344
IL6 interleukin 6 1.87875
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.85028
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.84429
MAOB monoamine oxidase B 1.84411
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.83148
CRH corticotropin releasing hormone 1.82237
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.79446
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.78168
JUN jun proto-oncogene 1.77917
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.77782
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.75797
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.756
CREB1 cAMP responsive element binding protein 1 1.755
DRD3 dopamine receptor D3 1.73938
NPY neuropeptide Y 1.72529
OPRM1 opioid receptor, mu 1 1.72322
DRD4 dopamine receptor D4 1.7105
PDYN prodynorphin 1.68019
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.6774
IFNG interferon, gamma 1.6677
MAPK8 mitogen-activated protein kinase 8 1.65842
EGR1 early growth response 1 1.65445
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.65358
IL1B interleukin 1, beta 1.64258
CCND1 cyclin D1 1.64168
HRH1 histamine receptor H1 1.63921
SOD1 superoxide dismutase 1, soluble 1.61713
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.61667
NOS2 nitric oxide synthase 2, inducible 1.60711
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.59778
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.59264
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.57665
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.57594
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.57474
GFAP glial fibrillary acidic protein 1.57378
CCL2 chemokine (C-C motif) ligand 2 1.56166
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.55599
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.54961
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.53675
MAOA monoamine oxidase A 1.53258
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.51784
CDK5 cyclin-dependent kinase 5 1.5143
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.5118
VEGFA vascular endothelial growth factor A 1.50248
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.48556
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.48273
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.48273
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.47089
NOS1 nitric oxide synthase 1 (neuronal) 1.46807
COMT catechol-O-methyltransferase 1.4559
IL10 interleukin 10 1.45115
GSTP1 glutathione S-transferase pi 1 1.45036
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.44599
HOMER1 homer scaffolding protein 1 1.44219
RELN reelin 1.44219
NGF nerve growth factor (beta polypeptide) 1.43755
NUPR1 nuclear protein, transcriptional regulator, 1 1.42129
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.42074
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.41285
SOD2 superoxide dismutase 2, mitochondrial 1.41119
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.4076
CXCL8 chemokine (C-X-C motif) ligand 8 1.40705
IL2 interleukin 2 1.39226
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.38807
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.38584
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.3827
ARC activity-regulated cytoskeleton-associated protein 1.3793
BCL2L1 BCL2-like 1 1.37705
LHB luteinizing hormone beta polypeptide 1.37275
RGS2 regulator of G-protein signaling 2 1.36763
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.36763
GRIK2 glutamate receptor, ionotropic, kainate 2 1.34343
GH1 growth hormone 1 1.34111
TP53 tumor protein p53 1.3388
HMOX1 heme oxygenase 1 1.33761
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.33701
FSHB follicle stimulating hormone, beta polypeptide 1.33553
TPH2 tryptophan hydroxylase 2 1.32756
JUNB jun B proto-oncogene 1.32399
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.32044
ADORA2A adenosine A2a receptor 1.31776
INS insulin 1.31656
CNR1 cannabinoid receptor 1 (brain) 1.31237
FAS Fas cell surface death receptor 1.30696
IL1A interleukin 1, alpha 1.30299
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.30087
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.30087
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.29936
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.29164
ADORA1 adenosine A1 receptor 1.27193
SYT5 synaptotagmin V 1.26886
REN renin 1.25494
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.2509
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.24874
ACHE acetylcholinesterase (Yt blood group) 1.2456
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.24118
EFNB3 ephrin-B3 1.23648
GDNF glial cell derived neurotrophic factor 1.23552
MAPK14 mitogen-activated protein kinase 14 1.23201
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.22048
GRM1 glutamate receptor, metabotropic 1 1.21759
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.2137
GPX1 glutathione peroxidase 1 1.21011
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.20622
TLR4 toll-like receptor 4 1.20427
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.20097
C10ORF10 chromosome 10 open reading frame 10 1.20097
FNDC4 fibronectin type III domain containing 4 1.20097
GRIK5 glutamate receptor, ionotropic, kainate 5 1.20064
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.20064
OPRK1 opioid receptor, kappa 1 1.19802
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.19509
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.19312
GRM5 glutamate receptor, metabotropic 5 1.19279
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.19213
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.18489
VIP vasoactive intestinal peptide 1.17761
DDIT3 DNA-damage-inducible transcript 3 1.17563
GRK6 G protein-coupled receptor kinase 6 1.1753
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.17399
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.17
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.16335
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.16203
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.16035
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.15797
NFE2L2 nuclear factor, erythroid 2-like 2 1.1556
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.15492
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.15223
PLP1 proteolipid protein 1 1.15189
PARP1 poly (ADP-ribose) polymerase 1 1.14816
AVP arginine vasopressin 1.14747
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.14678
OPRD1 opioid receptor, delta 1 1.14507
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.14268
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.14166
EFNA2 ephrin-A2 1.1403
RGS4 regulator of G-protein signaling 4 1.12872
GAST gastrin 1.12254
ELK1 ELK1, member of ETS oncogene family 1.12219
LDLR low density lipoprotein receptor 1.12082
APP amyloid beta (A4) precursor protein 1.11911
NTS neurotensin 1.11606
CCK cholecystokinin 1.10699
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.10665
PDIA6 protein disulfide isomerase family A, member 6 1.10665
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.10459
CCL5 chemokine (C-C motif) ligand 5 1.09716
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.09646
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.09506
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.09366
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.0919
INHA inhibin, alpha 1.0919
INHBE inhibin, beta E 1.0919
EDN1 endothelin 1 1.09083
S100B S100 calcium binding protein B 1.08619
IGF1 insulin-like growth factor 1 (somatomedin C) 1.08196
NPPA natriuretic peptide A 1.08161
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 1.07983
SYT4 synaptotagmin IV 1.07947
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.07947
DCXR dicarbonyl/L-xylulose reductase 1.07875
BAK1 BCL2-antagonist/killer 1 1.0766
FADD Fas (TNFRSF6)-associated via death domain 1.07234
ADCY8 adenylate cyclase 8 (brain) 1.07163
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.07022
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.06698
CCKBR cholecystokinin B receptor 1.05386
MAPT microtubule-associated protein tau 1.05349
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.05015
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.05015
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.04794
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.04611
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 1.04389
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.04314
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.04239
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.04201
AANAT aralkylamine N-acetyltransferase 1.03715
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.03567
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.03456
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 1.03456
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.03159
RGS8 regulator of G-protein signaling 8 1.03046
OXT oxytocin/neurophysin I prepropeptide 1.02559
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.02485
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.02373
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.02336
GNAS GNAS complex locus 1.02114
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.02114
CTSL cathepsin L 1.01852
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.01776
TGFB1 transforming growth factor, beta 1 1.01663
RGS9 regulator of G-protein signaling 9 1.01174