Caveola Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include any of the minute pits or incuppings of the cell membrane formed during pinocytosis. Such caveolae may be pinched off to form free vesicles within the cytoplasm. (Gene Ontology, GO_0005901)
External Link http://amigo.geneontology.org/amigo/term/GO:0005901
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Genes

57 proteins localized to the Caveola cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CAVIN4 caveolae associated protein 4 5.0
PTGIS prostaglandin I2 (prostacyclin) synthase 5.0
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 5.0
DLC1 DLC1 Rho GTPase activating protein 5.0
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5.0
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 5.0
CAV1 caveolin 1, caveolae protein, 22kDa 5.0
PLVAP plasmalemma vesicle associated protein 5.0
CLN3 ceroid-lipofuscinosis, neuronal 3 5.0
EHD2 EH-domain containing 2 5.0
KIF18A kinesin family member 18A 5.0
FLOT2 flotillin 2 5.0
PLPP2 phospholipid phosphatase 2 5.0
CAVIN1 caveolae associated protein 1 5.0
CAVIN3 caveolae associated protein 3 5.0
CAVIN2 caveolae associated protein 2 5.0
ADTRP androgen-dependent TFPI-regulating protein 5.0
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 5.0
HCK HCK proto-oncogene, Src family tyrosine kinase 5.0
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 5.0
NANOS3 nanos homolog 3 (Drosophila) 4.0
CORO1C coronin, actin binding protein, 1C 4.0
BVES blood vessel epicardial substance 4.0
SRC SRC proto-oncogene, non-receptor tyrosine kinase 4.0
MYOF myoferlin 4.0
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 4.0
RANGRF RAN guanine nucleotide release factor 4.0
MAPK1 mitogen-activated protein kinase 1 4.0
SELE selectin E 4.0
PLPP1 phospholipid phosphatase 1 4.0
SCN5A sodium channel, voltage gated, type V alpha subunit 4.0
IRS1 insulin receptor substrate 1 4.0
CAV2 caveolin 2 4.0
INSR insulin receptor 4.0
HDAC6 histone deacetylase 6 4.0
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 4.0
CDH13 cadherin 13 4.0
MAPK3 mitogen-activated protein kinase 3 4.0
LRRK2 leucine-rich repeat kinase 2 4.0
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 4.0
ADCY8 adenylate cyclase 8 (brain) 4.0
CAV3 caveolin 3 4.0
PTCH1 patched 1 4.0
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 4.0
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 4.0
FLOT1 flotillin 1 4.0
FXYD1 FXYD domain containing ion transport regulator 1 4.0
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 4.0
F2R coagulation factor II (thrombin) receptor 4.0
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 3.0
SORBS1 sorbin and SH3 domain containing 1 3.0
CD320 CD320 molecule 3.0
SCARB1 scavenger receptor class B, member 1 3.0
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 3.0
CD36 CD36 molecule (thrombospondin receptor) 3.0
JAK2 Janus kinase 2 3.0
AKAP6 A kinase (PRKA) anchor protein 6 3.0