| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.17185 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.124698 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.108334 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0983621 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0931548 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0862046 |
| B2M | beta-2-microglobulin | 0.0810737 |
| FLNB | filamin B, beta | 0.07059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0676919 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0661986 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0654139 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0599963 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0545806 |
| DST | dystonin | 0.0545534 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0532766 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.052029 |
| GOLGA4 | golgin A4 | 0.0516831 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0506639 |
| CD44 | CD44 molecule (Indian blood group) | 0.0495488 |
| TPM3 | tropomyosin 3 | 0.0489138 |
| RUNX1 | runt-related transcription factor 1 | 0.0476053 |
| RTN4 | reticulon 4 | 0.0464813 |
| DCLK2 | doublecortin-like kinase 2 | 0.0460681 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0456286 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.044775 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0441619 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.04392 |
| NDRG1 | N-myc downstream regulated 1 | 0.043473 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0434638 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0423249 |
| POTEF | POTE ankyrin domain family, member F | 0.0421993 |
| CD109 | CD109 molecule | 0.0420542 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.04132 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0407468 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0406381 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0406141 |
| SQSTM1 | sequestosome 1 | 0.040557 |
| SBF2 | SET binding factor 2 | 0.0394231 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0393142 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0385716 |
| MYOF | myoferlin | 0.03822 |
| MSN | moesin | 0.0379105 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0377602 |
| ATP13A3 | ATPase type 13A3 | 0.0375154 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0373918 |
| HELZ | helicase with zinc finger | 0.0370282 |
| CANX | calnexin | 0.0369092 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.036691 |
| MAP1B | microtubule-associated protein 1B | 0.0360817 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0354688 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0353639 |
| NAV2 | neuron navigator 2 | 0.0352704 |
| SETD5 | SET domain containing 5 | 0.0348352 |
| RAI1 | retinoic acid induced 1 | 0.0346956 |
| OGA | O-GlcNAcase | 0.0343906 |
| ZNF292 | zinc finger protein 292 | 0.0340237 |
| LOXL2 | lysyl oxidase-like 2 | 0.0337185 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0336778 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0335294 |
| FOSL1 | FOS-like antigen 1 | 0.0334487 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0329557 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0327237 |
| ADM | adrenomedullin | 0.0319311 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0318426 |
| RNF145 | ring finger protein 145 | 0.0317299 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0315872 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0314754 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0311236 |
| YEATS2 | YEATS domain containing 2 | 0.0310574 |
| FAM107B | family with sequence similarity 107, member B | 0.0309977 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0301442 |
| RNF24 | ring finger protein 24 | 0.0300729 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0299547 |
| PKM | pyruvate kinase, muscle | 0.0295676 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0295663 |
| MEIS2 | Meis homeobox 2 | 0.0295358 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.029281 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.029262 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0291677 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0291042 |
| DSPP | dentin sialophosphoprotein | 0.0290312 |
| XPO1 | exportin 1 | 0.0289587 |
| ARRDC3 | arrestin domain containing 3 | 0.0288337 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0286428 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0286074 |
| OPTN | optineurin | 0.0285993 |
| SUCO | SUN domain containing ossification factor | 0.0283963 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0280182 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0279224 |
| UBC | ubiquitin C | 0.0274258 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0273768 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0269772 |
| COPA | coatomer protein complex, subunit alpha | 0.0269378 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0268949 |
| TGFB1 | transforming growth factor, beta 1 | 0.0267752 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0264157 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0262482 |
| CALR | calreticulin | 0.0260396 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0259818 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.025823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAT | plasminogen activator, tissue | -0.105549 |
| CDH13 | cadherin 13 | -0.102965 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0990828 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0704743 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0631518 |
| VIM | vimentin | -0.0621719 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.05991 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0579001 |
| INTS6 | integrator complex subunit 6 | -0.0505895 |
| S100A10 | S100 calcium binding protein A10 | -0.0471552 |
| PODXL | podocalyxin-like | -0.0449547 |
| RPL37A | ribosomal protein L37a | -0.0414788 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0408949 |
| CAVIN1 | caveolae associated protein 1 | -0.0394084 |
| COL3A1 | collagen, type III, alpha 1 | -0.039272 |
| EFNA5 | ephrin-A5 | -0.0392297 |
| COL5A1 | collagen, type V, alpha 1 | -0.037706 |
| RPS8 | ribosomal protein S8 | -0.0374079 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0368737 |
| CYTH3 | cytohesin 3 | -0.0361452 |
| SUCNR1 | succinate receptor 1 | -0.0359033 |
| LOX | lysyl oxidase | -0.0355265 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0350965 |
| RPL35A | ribosomal protein L35a | -0.0350292 |
| RPS24 | ribosomal protein S24 | -0.0341983 |
| FRMD4A | FERM domain containing 4A | -0.0328322 |
| RPL23 | ribosomal protein L23 | -0.0325678 |
| MT2A | metallothionein 2A | -0.030929 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0304539 |
| EGFR | epidermal growth factor receptor | -0.02895 |
| RPS3 | ribosomal protein S3 | -0.0286409 |
| RPL34 | ribosomal protein L34 | -0.0285794 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0285756 |
| VCL | vinculin | -0.0285423 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0276491 |
| THBS2 | thrombospondin 2 | -0.0275523 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0274668 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0272321 |
| CTSB | cathepsin B | -0.0261488 |
| HLA-E | major histocompatibility complex, class I, E | -0.0256993 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0251127 |
| AEBP2 | AE binding protein 2 | -0.0243656 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0238956 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0238922 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0235801 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0227522 |
| RASAL2 | RAS protein activator like 2 | -0.022318 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0222019 |
| IPO9 | importin 9 | -0.0221899 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.022185 |
| HLA-B | major histocompatibility complex, class I, B | -0.0213989 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0210459 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0208636 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0202322 |
| RPS27A | ribosomal protein S27a | -0.0200435 |
| FTL | ferritin, light polypeptide | -0.0198555 |
| RPL12 | ribosomal protein L12 | -0.0196688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0194764 |
| ACTG1 | actin gamma 1 | -0.0194339 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0193871 |
| RPS17 | ribosomal protein S17 | -0.0192652 |
| NABP1 | nucleic acid binding protein 1 | -0.0190391 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0188931 |
| RPS16 | ribosomal protein S16 | -0.018823 |
| CUX1 | cut-like homeobox 1 | -0.0186969 |
| MELTF | melanotransferrin | -0.0182944 |
| RPL31 | ribosomal protein L31 | -0.0182815 |
| TNS3 | tensin 3 | -0.0182321 |
| RPL9 | ribosomal protein L9 | -0.0181435 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0179473 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0179148 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0177987 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0176189 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0176014 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0172562 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0172265 |
| RPL28 | ribosomal protein L28 | -0.0171653 |
| XG | Xg blood group | -0.0171482 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0171293 |
| RPS14 | ribosomal protein S14 | -0.0169655 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0169052 |
| RPS13 | ribosomal protein S13 | -0.0168712 |
| COL1A2 | collagen, type I, alpha 2 | -0.0167369 |
| TBCA | tubulin folding cofactor A | -0.0165468 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0162102 |
| RPS15 | ribosomal protein S15 | -0.0161263 |
| SLFN5 | schlafen family member 5 | -0.0160575 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0159975 |
| CCDC138 | coiled-coil domain containing 138 | -0.0157376 |
| RPL37 | ribosomal protein L37 | -0.0157004 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0156191 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0155779 |
| CDK13 | cyclin-dependent kinase 13 | -0.0155637 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0152764 |
| CCND1 | cyclin D1 | -0.0151843 |
| NLGN4Y | neuroligin 4, Y-linked | -0.015173 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0149931 |
| RPL26 | ribosomal protein L26 | -0.0149748 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0149584 |
| RPLP2 | ribosomal protein, large, P2 | -0.0149479 |
