| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.131067 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.114168 |
| TMSB10 | thymosin beta 10 | 0.100005 |
| NLGN1 | neuroligin 1 | 0.0968938 |
| YAP1 | Yes-associated protein 1 | 0.0836674 |
| WWOX | WW domain containing oxidoreductase | 0.0668361 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.064741 |
| PFN1 | profilin 1 | 0.0561322 |
| PCBP2 | poly(rC) binding protein 2 | 0.0558204 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0534992 |
| EPHA6 | EPH receptor A6 | 0.0499662 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0495965 |
| TENM3 | teneurin transmembrane protein 3 | 0.047767 |
| VMP1 | vacuole membrane protein 1 | 0.047366 |
| ANKRD12 | ankyrin repeat domain 12 | 0.047273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0467332 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.045682 |
| POTEF | POTE ankyrin domain family, member F | 0.0456746 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0452713 |
| PTMS | parathymosin | 0.0451722 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.044821 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0447266 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0435929 |
| IPO7 | importin 7 | 0.0429167 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0422305 |
| PCDH7 | protocadherin 7 | 0.0412218 |
| PCDH9 | protocadherin 9 | 0.0378292 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0378201 |
| TBK1 | TANK-binding kinase 1 | 0.0365933 |
| TXNRD1 | thioredoxin reductase 1 | 0.0350548 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0350131 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0347546 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0320206 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0316586 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.031332 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0312246 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0309337 |
| PRELID2 | PRELI domain containing 2 | 0.0306202 |
| RPS19 | ribosomal protein S19 | 0.0291043 |
| RSF1 | remodeling and spacing factor 1 | 0.0283019 |
| CPOX | coproporphyrinogen oxidase | 0.0282273 |
| CCNL1 | cyclin L1 | 0.0280658 |
| CCDC88A | coiled-coil domain containing 88A | 0.0280412 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0279334 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0276176 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0275494 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.027294 |
| TMEM41B | transmembrane protein 41B | 0.027172 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0265496 |
| RPS4X | ribosomal protein S4, X-linked | 0.0264094 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0262677 |
| EML6 | echinoderm microtubule associated protein like 6 | 0.0260825 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0255264 |
| ATP11A | ATPase, class VI, type 11A | 0.025521 |
| CDK6 | cyclin-dependent kinase 6 | 0.0247024 |
| ZNF207 | zinc finger protein 207 | 0.0240332 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0240243 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0239494 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0235923 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0234913 |
| RBM25 | RNA binding motif protein 25 | 0.0231388 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.023131 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0228433 |
| NBAS | neuroblastoma amplified sequence | 0.0225297 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0223943 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0221113 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0221008 |
| CBX3 | chromobox homolog 3 | 0.0220118 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0216636 |
| SQSTM1 | sequestosome 1 | 0.0214982 |
| ARRDC3 | arrestin domain containing 3 | 0.0214573 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0213422 |
| EPHA5 | EPH receptor A5 | 0.0213398 |
| HELLS | helicase, lymphoid-specific | 0.0211381 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0211184 |
| RPS6 | ribosomal protein S6 | 0.0210993 |
| ZNF292 | zinc finger protein 292 | 0.0209801 |
| FHIT | fragile histidine triad | 0.0209344 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0207866 |
| ANXA5 | annexin A5 | 0.0204386 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0203725 |
| LDHA | lactate dehydrogenase A | 0.0203325 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0203161 |
| JMJD1C | jumonji domain containing 1C | 0.0203131 |
| YBX1 | Y box binding protein 1 | 0.0202184 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0200676 |
| CEP126 | centrosomal protein 126kDa | 0.0198112 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.019769 |
| TUSC3 | tumor suppressor candidate 3 | 0.0197512 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0196887 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0196141 |
| PCM1 | pericentriolar material 1 | 0.0192079 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.0191714 |
| SON | SON DNA binding protein | 0.0190394 |
| ATP11B | ATPase, class VI, type 11B | 0.0186412 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0186395 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0186182 |
| TNPO1 | transportin 1 | 0.0185915 |
| TPM3 | tropomyosin 3 | 0.0185631 |
| PNN | pinin, desmosome associated protein | 0.0185078 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0815177 |
| RPL26 | ribosomal protein L26 | -0.0788038 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0678458 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0650543 |
| RPL37A | ribosomal protein L37a | -0.0625341 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0611683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0601753 |
| LMO7 | LIM domain 7 | -0.0587451 |
| MMP12 | matrix metallopeptidase 12 | -0.0562761 |
| AREG | amphiregulin | -0.0548186 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0545399 |
| RPS27A | ribosomal protein S27a | -0.0514483 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0514132 |
| CLDN1 | claudin 1 | -0.0505505 |
| RASAL2 | RAS protein activator like 2 | -0.0482377 |
| RPL35A | ribosomal protein L35a | -0.0477004 |
| RPS8 | ribosomal protein S8 | -0.0470591 |
| RPS12 | ribosomal protein S12 | -0.0461452 |
| GCG | glucagon | -0.0457981 |
| RPS3 | ribosomal protein S3 | -0.0455774 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0446982 |
| ANXA1 | annexin A1 | -0.0446943 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0426868 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0422797 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0422652 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0418687 |
| PTMA | prothymosin, alpha | -0.0416869 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0415969 |
| CAVIN1 | caveolae associated protein 1 | -0.0393664 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0391023 |
| RPL11 | ribosomal protein L11 | -0.0390865 |
| CMIP | c-Maf inducing protein | -0.0389685 |
| DST | dystonin | -0.0378678 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0372408 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0361003 |
| RPS29 | ribosomal protein S29 | -0.03563 |
| MYPN | myopalladin | -0.03535 |
| ZNF804A | zinc finger protein 804A | -0.0351754 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0350166 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0347796 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.034072 |
| RPL12 | ribosomal protein L12 | -0.0340131 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0338807 |
| ZNF217 | zinc finger protein 217 | -0.0335018 |
| RPS24 | ribosomal protein S24 | -0.0334557 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0330967 |
| RPL31 | ribosomal protein L31 | -0.0330068 |
| RPS13 | ribosomal protein S13 | -0.0330025 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0321085 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0319642 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0314358 |
| VIM | vimentin | -0.0309565 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0293336 |
| SYT1 | synaptotagmin I | -0.0292394 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0287705 |
| BCHE | butyrylcholinesterase | -0.0285554 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0285202 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0278908 |
| EGFR | epidermal growth factor receptor | -0.027665 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0273238 |
| RPL13A | ribosomal protein L13a | -0.0266773 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0263332 |
| COMMD10 | COMM domain containing 10 | -0.0262068 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0258239 |
| RPS25 | ribosomal protein S25 | -0.0256634 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0252811 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0251115 |
| SLC38A2 | solute carrier family 38, member 2 | -0.024965 |
| CENPF | centromere protein F, 350/400kDa | -0.0248944 |
| RPL38 | ribosomal protein L38 | -0.02473 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0242516 |
| EZR | ezrin | -0.0239419 |
| RPS23 | ribosomal protein S23 | -0.0239407 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0235992 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0234587 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0234293 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0231622 |
| TPR | translocated promoter region, nuclear basket protein | -0.0229362 |
| INTS6 | integrator complex subunit 6 | -0.0228773 |
| FTL | ferritin, light polypeptide | -0.0227503 |
| RPS16 | ribosomal protein S16 | -0.0227338 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0222625 |
| MAP4 | microtubule-associated protein 4 | -0.0221108 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0220604 |
| WASF2 | WAS protein family, member 2 | -0.0220566 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0219823 |
| ERBIN | erbb2 interacting protein | -0.0218936 |
| HMGA2 | high mobility group AT-hook 2 | -0.0217746 |
| RPS17 | ribosomal protein S17 | -0.0217542 |
| EHBP1 | EH domain binding protein 1 | -0.0211851 |
| PRDX1 | peroxiredoxin 1 | -0.0209045 |
| RPL23 | ribosomal protein L23 | -0.0208796 |
| RAI14 | retinoic acid induced 14 | -0.0208379 |
| RACK1 | receptor for activated C kinase 1 | -0.0207238 |
| KIF5B | kinesin family member 5B | -0.0206925 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0206539 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0205701 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0204514 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.0204174 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0203151 |
