| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.168385 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.146182 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0822178 |
| VEGFA | vascular endothelial growth factor A | 0.0811255 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0769682 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0763704 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0746934 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0719992 |
| CADM1 | cell adhesion molecule 1 | 0.0669021 |
| MT2A | metallothionein 2A | 0.0617859 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0567893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0517167 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0513204 |
| ENO1 | enolase 1, (alpha) | 0.0463852 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0457315 |
| CDH13 | cadherin 13 | 0.0456435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.045566 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0441151 |
| RPS8 | ribosomal protein S8 | 0.0425445 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0365712 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0363591 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0359519 |
| NAV2 | neuron navigator 2 | 0.0331914 |
| RPS12 | ribosomal protein S12 | 0.0330433 |
| B2M | beta-2-microglobulin | 0.0325714 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0325059 |
| RPS6 | ribosomal protein S6 | 0.0323214 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0322493 |
| S100A9 | S100 calcium binding protein A9 | 0.0310834 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0307788 |
| EGFR | epidermal growth factor receptor | 0.0307311 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0302447 |
| RPS3 | ribosomal protein S3 | 0.0296053 |
| MYO10 | myosin X | 0.0289025 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0285889 |
| RUNX1 | runt-related transcription factor 1 | 0.0283588 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.027202 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0259862 |
| RPS19 | ribosomal protein S19 | 0.0255165 |
| SQSTM1 | sequestosome 1 | 0.0253201 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0252587 |
| PGM3 | phosphoglucomutase 3 | 0.0251559 |
| RPL37A | ribosomal protein L37a | 0.0246564 |
| ADM | adrenomedullin | 0.0243442 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0241552 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0239004 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0235364 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.023531 |
| FMNL2 | formin-like 2 | 0.0234966 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.023223 |
| POTEF | POTE ankyrin domain family, member F | 0.0230243 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0224993 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0223396 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0223191 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0219108 |
| ZNF292 | zinc finger protein 292 | 0.0216679 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0216485 |
| ANXA1 | annexin A1 | 0.0212344 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.021225 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0211427 |
| YBX1 | Y box binding protein 1 | 0.020759 |
| FAM219A | family with sequence similarity 219, member A | 0.0205273 |
| RPLP2 | ribosomal protein, large, P2 | 0.0202862 |
| PKM | pyruvate kinase, muscle | 0.0200805 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0200672 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196441 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0194909 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0194607 |
| TNS1 | tensin 1 | 0.0192077 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0191822 |
| ARRDC3 | arrestin domain containing 3 | 0.0191313 |
| IL6 | interleukin 6 | 0.0189946 |
| HYOU1 | hypoxia up-regulated 1 | 0.0187658 |
| IER3 | immediate early response 3 | 0.0187629 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0181219 |
| PDE10A | phosphodiesterase 10A | 0.0180646 |
| BRD4 | bromodomain containing 4 | 0.0179379 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0178976 |
| MSN | moesin | 0.0177965 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0177936 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0175051 |
| HIP1 | huntingtin interacting protein 1 | 0.017366 |
| PTMA | prothymosin, alpha | 0.0173236 |
| RPL36 | ribosomal protein L36 | 0.0172824 |
| MYO1B | myosin IB | 0.0172467 |
| RPL7 | ribosomal protein L7 | 0.0172303 |
| BBX | bobby sox homolog (Drosophila) | 0.017013 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.016907 |
| EFNA5 | ephrin-A5 | 0.0169023 |
| RPS2 | ribosomal protein S2 | 0.016835 |
| QKI | QKI, KH domain containing, RNA binding | 0.0167468 |
| FAM120A | family with sequence similarity 120A | 0.016696 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0166493 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0165884 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0164759 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0162717 |
| ASPH | aspartate beta-hydroxylase | 0.0161403 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0160271 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0160078 |
| CA12 | carbonic anhydrase XII | 0.0158936 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.231899 |
| COL1A1 | collagen, type I, alpha 1 | -0.142106 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0931035 |
| VIM | vimentin | -0.0745184 |
| COL1A2 | collagen, type I, alpha 2 | -0.0684217 |
| HMGA2 | high mobility group AT-hook 2 | -0.0604062 |
| GLIS3 | GLIS family zinc finger 3 | -0.0603903 |
| LOX | lysyl oxidase | -0.0587313 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0532543 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0528385 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0502614 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0499994 |
| FBN1 | fibrillin 1 | -0.0494675 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.04641 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0457927 |
| PALLD | palladin, cytoskeletal associated protein | -0.0426111 |
| VCL | vinculin | -0.0411581 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0410736 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0399242 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0396192 |
| OSMR | oncostatin M receptor | -0.0380067 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0368639 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0357862 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0334805 |
| CD44 | CD44 molecule (Indian blood group) | -0.0325504 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0319405 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.030551 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0290375 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0284248 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0255959 |
| RRBP1 | ribosome binding protein 1 | -0.025426 |
| RAD21 | RAD21 homolog (S. pombe) | -0.024535 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0235317 |
| EGR1 | early growth response 1 | -0.0233378 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0232198 |
| RSU1 | Ras suppressor protein 1 | -0.0229 |
| ACTG1 | actin gamma 1 | -0.0228582 |
| TPM4 | tropomyosin 4 | -0.0228179 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0224486 |
| ANXA2 | annexin A2 | -0.022088 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0220018 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.021528 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0213183 |
| MT1X | metallothionein 1X | -0.0210238 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0209767 |
| MAP1B | microtubule-associated protein 1B | -0.0209395 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0206851 |
| RIGI | RNA sensor RIG-I | -0.0203664 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0203385 |
| CAVIN1 | caveolae associated protein 1 | -0.0203117 |
| VCAN | versican | -0.0202963 |
| EBF1 | early B-cell factor 1 | -0.0201278 |
| NREP | neuronal regeneration related protein | -0.0199449 |
| CALD1 | caldesmon 1 | -0.0199288 |
| SPAG9 | sperm associated antigen 9 | -0.0187116 |
| JAK2 | Janus kinase 2 | -0.0182031 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0181965 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0178099 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0177251 |
| ATM | ATM serine/threonine kinase | -0.0173543 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0172378 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0172156 |
| ERBIN | erbb2 interacting protein | -0.0171159 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0170651 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.0170189 |
| FRMD4A | FERM domain containing 4A | -0.0169954 |
| KLF6 | Kruppel-like factor 6 | -0.0169113 |
| HDLBP | high density lipoprotein binding protein | -0.0167518 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0165753 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0161043 |
| CALU | calumenin | -0.0159903 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0156799 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0150298 |
| ARF1 | ADP-ribosylation factor 1 | -0.0147677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0147597 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0146734 |
| TPM1 | tropomyosin 1 (alpha) | -0.0144918 |
| AK1 | adenylate kinase 1 | -0.0144487 |
| POSTN | periostin, osteoblast specific factor | -0.0141634 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0141 |
| TENM1 | teneurin transmembrane protein 1 | -0.0139969 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0139833 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0138919 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0138686 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0136883 |
| AHNAK | AHNAK nucleoprotein | -0.0136642 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0134979 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.013371 |
| FAM20C | family with sequence similarity 20, member C | -0.0133306 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0132186 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0130956 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0130035 |
| FHL2 | four and a half LIM domains 2 | -0.0129873 |
| SMYD3 | SET and MYND domain containing 3 | -0.0129756 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0128981 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0127778 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.0127564 |
| ZNF644 | zinc finger protein 644 | -0.012704 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0126336 |
| NF1 | neurofibromin 1 | -0.0125911 |
