| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111708 |
| TMSB10 | thymosin beta 10 | 0.103931 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0944985 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0831619 |
| B2M | beta-2-microglobulin | 0.0801738 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0604952 |
| TXNRD1 | thioredoxin reductase 1 | 0.0585764 |
| GOLGA4 | golgin A4 | 0.0565874 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0560893 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0560174 |
| TMC5 | transmembrane channel-like 5 | 0.0486895 |
| ANXA1 | annexin A1 | 0.048266 |
| S100A6 | S100 calcium binding protein A6 | 0.0476333 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0454945 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0452449 |
| FTL | ferritin, light polypeptide | 0.0446112 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0424464 |
| AGR3 | anterior gradient 3 | 0.0422981 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0411289 |
| EZR | ezrin | 0.0405009 |
| TES | testin LIM domain protein | 0.0397388 |
| S100A9 | S100 calcium binding protein A9 | 0.0394933 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0390736 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0383883 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0373576 |
| ATF5 | activating transcription factor 5 | 0.0356523 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0356103 |
| AGR2 | anterior gradient 2 | 0.0351398 |
| RPS19 | ribosomal protein S19 | 0.0350731 |
| RPS6 | ribosomal protein S6 | 0.0349743 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0330561 |
| KRT18 | keratin 18, type I | 0.0326185 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0325593 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0321846 |
| DSTN | destrin (actin depolymerizing factor) | 0.0318926 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0318843 |
| ASTN2 | astrotactin 2 | 0.0317539 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0317162 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0304509 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0297721 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0294133 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0290297 |
| H1-0 | H1.0 linker histone | 0.0288627 |
| PFN1 | profilin 1 | 0.0284597 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0283876 |
| EMP1 | epithelial membrane protein 1 | 0.0277269 |
| MYADM | myeloid-associated differentiation marker | 0.0274538 |
| POTEF | POTE ankyrin domain family, member F | 0.027104 |
| CLDN7 | claudin 7 | 0.0270051 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0267247 |
| LIMA1 | LIM domain and actin binding 1 | 0.0261757 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0260249 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0256687 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0254437 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0253244 |
| ENO1 | enolase 1, (alpha) | 0.0252294 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0251683 |
| RPL23 | ribosomal protein L23 | 0.0251472 |
| RPL32 | ribosomal protein L32 | 0.0249367 |
| PLS1 | plastin 1 | 0.0248088 |
| CALR | calreticulin | 0.024691 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0245465 |
| HYOU1 | hypoxia up-regulated 1 | 0.0245287 |
| RPL18 | ribosomal protein L18 | 0.0239591 |
| SNX9 | sorting nexin 9 | 0.023811 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0237442 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0236091 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0227157 |
| PGK1 | phosphoglycerate kinase 1 | 0.0221771 |
| RPS25 | ribosomal protein S25 | 0.022059 |
| RPL12 | ribosomal protein L12 | 0.0218818 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0218387 |
| CLTC | clathrin, heavy chain (Hc) | 0.0218192 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0217821 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0216633 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0216391 |
| TMEM45B | transmembrane protein 45B | 0.0215754 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0215298 |
| PTMA | prothymosin, alpha | 0.0213414 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0212726 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0212372 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0211421 |
| RPL8 | ribosomal protein L8 | 0.0210097 |
| TRAM1 | translocation associated membrane protein 1 | 0.0207627 |
| S100A11 | S100 calcium binding protein A11 | 0.0203368 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0202218 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0201802 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0201563 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0201461 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.02013 |
| TMSB4X | thymosin beta 4, X-linked | 0.0200413 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.0198383 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0197289 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0196782 |
| COG5 | component of oligomeric golgi complex 5 | 0.0196571 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0194521 |
| SFTPA2 | surfactant protein A2 | 0.0194412 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0194114 |
| RPL19 | ribosomal protein L19 | 0.0193283 |
| TXNIP | thioredoxin interacting protein | 0.0191753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.291274 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.185952 |
| NPSR1 | neuropeptide S receptor 1 | -0.162226 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.150575 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.111506 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0873383 |
| INTS6 | integrator complex subunit 6 | -0.0652647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0609161 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0551224 |
| FLNB | filamin B, beta | -0.0528118 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0512416 |
| RUNX1 | runt-related transcription factor 1 | -0.0490933 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0416267 |
| TFRC | transferrin receptor | -0.0410047 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0401342 |
| EHBP1 | EH domain binding protein 1 | -0.0390676 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0377755 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0374948 |
| ATXN1 | ataxin 1 | -0.0372798 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0372389 |
| VCL | vinculin | -0.0369345 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0369287 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368564 |
| FRMD5 | FERM domain containing 5 | -0.0360141 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.035685 |
| CDK6 | cyclin-dependent kinase 6 | -0.0356363 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0352765 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0343321 |
| MECOM | MDS1 and EVI1 complex locus | -0.034159 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0341207 |
| YAP1 | Yes-associated protein 1 | -0.0340797 |
| POF1B | premature ovarian failure, 1B | -0.0336769 |
| CTBP2 | C-terminal binding protein 2 | -0.0327138 |
| PRKCA | protein kinase C, alpha | -0.031884 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0314353 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0308971 |
| ACTG1 | actin gamma 1 | -0.030336 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0303127 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0303088 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0297283 |
| MSI2 | musashi RNA-binding protein 2 | -0.0296943 |
| AHNAK | AHNAK nucleoprotein | -0.0293763 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.029281 |
| FAT1 | FAT atypical cadherin 1 | -0.0287922 |
| RAD51B | RAD51 paralog B | -0.0285905 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0284503 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0282831 |
| MYO1E | myosin IE | -0.0272959 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0269799 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0267494 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.026019 |
| AEBP2 | AE binding protein 2 | -0.0256792 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.025503 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0252021 |
| ACTN4 | actinin, alpha 4 | -0.0248583 |
| PHF14 | PHD finger protein 14 | -0.0247527 |
| CAPN8 | calpain 8 | -0.0245966 |
| CNKSR3 | CNKSR family member 3 | -0.0245953 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0244284 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.024291 |
| EGFR | epidermal growth factor receptor | -0.0242443 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0242149 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0241877 |
| NFIA | nuclear factor I/A | -0.0240513 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0240032 |
| RNF213 | ring finger protein 213 | -0.0238533 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0237162 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0234572 |
| HLA-C | major histocompatibility complex, class I, C | -0.0232508 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0232483 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0230949 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0230496 |
| GPHN | gephyrin | -0.0229339 |
| XYLT1 | xylosyltransferase I | -0.0227539 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0226409 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0226118 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0225959 |
| WWOX | WW domain containing oxidoreductase | -0.0225666 |
| FUS | FUS RNA binding protein | -0.0224079 |
| DIAPH2 | diaphanous-related formin 2 | -0.0223635 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0223506 |
| KRT86 | keratin 86, type II | -0.0221988 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0219506 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0219308 |
| PLEC | plectin | -0.0216891 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0215478 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0214298 |
| AUTS2 | autism susceptibility candidate 2 | -0.0213668 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0213362 |
| FBXO11 | F-box protein 11 | -0.0212191 |
| DENND1A | DENN/MADD domain containing 1A | -0.0210851 |
| ABR | active BCR-related | -0.0210105 |
| UBAP2 | ubiquitin associated protein 2 | -0.0209925 |
| PALLD | palladin, cytoskeletal associated protein | -0.0209571 |
| CENPP | centromere protein P | -0.0209131 |
| CFAP161 | cilia and flagella associated protein 161 | -0.0208431 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0206924 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0206546 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0205837 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0205094 |
