| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117532 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0596282 |
| TXNIP | thioredoxin interacting protein | 0.0402241 |
| H1-0 | H1.0 linker histone | 0.0389023 |
| PTMA | prothymosin, alpha | 0.0369582 |
| MED13 | mediator complex subunit 13 | 0.0307292 |
| CALR | calreticulin | 0.0306591 |
| MT2A | metallothionein 2A | 0.0300355 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0292491 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0286767 |
| RNF145 | ring finger protein 145 | 0.0275699 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0268921 |
| GOLGA4 | golgin A4 | 0.0264069 |
| RPL32 | ribosomal protein L32 | 0.0254635 |
| PLS1 | plastin 1 | 0.0247097 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0229498 |
| MT1X | metallothionein 1X | 0.0228178 |
| TMF1 | TATA element modulatory factor 1 | 0.0224279 |
| CENPF | centromere protein F, 350/400kDa | 0.0210398 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0208714 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.020508 |
| TMSB10 | thymosin beta 10 | 0.0198638 |
| FAM13A | family with sequence similarity 13, member A | 0.0198598 |
| ENO1 | enolase 1, (alpha) | 0.0198353 |
| CANX | calnexin | 0.0197704 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0195875 |
| RPL18 | ribosomal protein L18 | 0.0192062 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0185924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0183709 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.017991 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0179277 |
| EZR | ezrin | 0.0174276 |
| USP6NL | USP6 N-terminal like | 0.0170487 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0169805 |
| KRT8 | keratin 8, type II | 0.0169447 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0168964 |
| ANXA1 | annexin A1 | 0.0163797 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0161489 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0161351 |
| PFN1 | profilin 1 | 0.0158887 |
| KRT18 | keratin 18, type I | 0.0155448 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0154299 |
| ZNF292 | zinc finger protein 292 | 0.0153366 |
| VEGFA | vascular endothelial growth factor A | 0.0147156 |
| NKTR | natural killer cell triggering receptor | 0.0144942 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0144599 |
| PCM1 | pericentriolar material 1 | 0.0141552 |
| POTEF | POTE ankyrin domain family, member F | 0.0140272 |
| PDZD8 | PDZ domain containing 8 | 0.0139869 |
| LMO7 | LIM domain 7 | 0.0137322 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0136266 |
| WHRN | whirlin | 0.013583 |
| HMGB2 | high mobility group box 2 | 0.0135511 |
| DSPP | dentin sialophosphoprotein | 0.0135316 |
| SON | SON DNA binding protein | 0.0134526 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0134213 |
| TFG | TRK-fused gene | 0.0134192 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0133419 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0132867 |
| RPS19 | ribosomal protein S19 | 0.0132732 |
| WASF2 | WAS protein family, member 2 | 0.0132113 |
| RPL36 | ribosomal protein L36 | 0.0132048 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0129337 |
| MLF1 | myeloid leukemia factor 1 | 0.012858 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0127537 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0126692 |
| MT1G | metallothionein 1G | 0.0126643 |
| HYOU1 | hypoxia up-regulated 1 | 0.0126301 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0124163 |
| RRBP1 | ribosome binding protein 1 | 0.0121558 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0121439 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0121054 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0120781 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0119427 |
| TES | testin LIM domain protein | 0.0119406 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0118426 |
| COPA | coatomer protein complex, subunit alpha | 0.0118132 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0118059 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0116459 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0116263 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0111401 |
| TSPAN3 | tetraspanin 3 | 0.0111024 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0110463 |
| OGA | O-GlcNAcase | 0.0110058 |
| CEP290 | centrosomal protein 290kDa | 0.0109062 |
| EXPH5 | exophilin 5 | 0.0108692 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0108325 |
| RPL3 | ribosomal protein L3 | 0.0108209 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0107794 |
| REST | RE1-silencing transcription factor | 0.0107235 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0107021 |
| TPD52 | tumor protein D52 | 0.0103723 |
| ASPH | aspartate beta-hydroxylase | 0.0103555 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0103176 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0102626 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.0102247 |
| ZFP36 | ZFP36 ring finger protein | 0.0101883 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.010164 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.010075 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0100596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.144278 |
| VCL | vinculin | -0.119684 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11711 |
| NPSR1 | neuropeptide S receptor 1 | -0.116618 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.114921 |
| MYO1E | myosin IE | -0.0787977 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0677306 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0615509 |
| ANXA2 | annexin A2 | -0.0523713 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0503574 |
| ONECUT3 | one cut homeobox 3 | -0.0488313 |
| LAMA4 | laminin, alpha 4 | -0.0476356 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0475814 |
| TPM4 | tropomyosin 4 | -0.0453881 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0453589 |
| IER3 | immediate early response 3 | -0.0452041 |
| RPS27A | ribosomal protein S27a | -0.0440476 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0438838 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0428829 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0410462 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0381571 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0380314 |
| FHL2 | four and a half LIM domains 2 | -0.0378833 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0372532 |
| FLNB | filamin B, beta | -0.0364873 |
| RPS8 | ribosomal protein S8 | -0.0361139 |
| FHIT | fragile histidine triad | -0.0357669 |
| GPHN | gephyrin | -0.0349644 |
| RIGI | RNA sensor RIG-I | -0.0343769 |
| SMYD3 | SET and MYND domain containing 3 | -0.0329147 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0317736 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0317719 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0315328 |
| RPL35A | ribosomal protein L35a | -0.031179 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0306189 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0300123 |
| PALLD | palladin, cytoskeletal associated protein | -0.0297786 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0295213 |
| PIGR | polymeric immunoglobulin receptor | -0.0292697 |
| TNS4 | tensin 4 | -0.0289982 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0282236 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0276257 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0272182 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0270286 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0269987 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0260854 |
| POF1B | premature ovarian failure, 1B | -0.0260452 |
| RPS24 | ribosomal protein S24 | -0.0258038 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0255815 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0252932 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0251778 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0250263 |
| RPL9 | ribosomal protein L9 | -0.024847 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0246271 |
| RPS20 | ribosomal protein S20 | -0.0245808 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0244391 |
| TFF1 | trefoil factor 1 | -0.0244035 |
| EGR1 | early growth response 1 | -0.0240992 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0240823 |
| RAB10 | RAB10, member RAS oncogene family | -0.0232922 |
| RPL26 | ribosomal protein L26 | -0.023194 |
| ABR | active BCR-related | -0.0230149 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0230044 |
| RPL31 | ribosomal protein L31 | -0.0224688 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0221448 |
| AHNAK | AHNAK nucleoprotein | -0.0220293 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0219284 |
| FBXO11 | F-box protein 11 | -0.0215381 |
| CUX1 | cut-like homeobox 1 | -0.0214733 |
| RPL37 | ribosomal protein L37 | -0.021224 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0210613 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0208042 |
| TFF3 | trefoil factor 3 (intestinal) | -0.020799 |
| PKP2 | plakophilin 2 | -0.0207207 |
| RPL34 | ribosomal protein L34 | -0.020669 |
| RPS25 | ribosomal protein S25 | -0.020594 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0205518 |
| ACTG1 | actin gamma 1 | -0.0205449 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0205412 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0205326 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0204505 |
| SPAG9 | sperm associated antigen 9 | -0.0204249 |
| DIAPH2 | diaphanous-related formin 2 | -0.0204028 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0203401 |
| RPL12 | ribosomal protein L12 | -0.0201269 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0198879 |
| HEPH | hephaestin | -0.0198542 |
| MUC17 | mucin 17, cell surface associated | -0.01957 |
| PCDH9 | protocadherin 9 | -0.0194538 |
| PRSS3 | protease, serine, 3 | -0.0192587 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.019176 |
| RAD51B | RAD51 paralog B | -0.019029 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0189761 |
| GPR39 | G protein-coupled receptor 39 | -0.0188927 |
| ACTN4 | actinin, alpha 4 | -0.0188593 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0187648 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0186681 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0184868 |
| S100A6 | S100 calcium binding protein A6 | -0.0184748 |
| DENND1A | DENN/MADD domain containing 1A | -0.0183174 |
