| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.043299 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0389508 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0361564 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0353435 |
| GRAMD1B | GRAM domain containing 1B | 0.0335143 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0298714 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0253903 |
| INTS6 | integrator complex subunit 6 | 0.0211912 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0195005 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0192495 |
| MT2A | metallothionein 2A | 0.0184736 |
| PYGL | phosphorylase, glycogen, liver | 0.0162853 |
| RAD51B | RAD51 paralog B | 0.0161889 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0142882 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0141266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0135282 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0125106 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0121764 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0117461 |
| SIK3 | SIK family kinase 3 | 0.0115968 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0112005 |
| DTNA | dystrobrevin, alpha | 0.011126 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0111133 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.010866 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0106308 |
| BMP6 | bone morphogenetic protein 6 | 0.0100457 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00994898 |
| ATP11A | ATPase, class VI, type 11A | 0.00983919 |
| ATF6 | activating transcription factor 6 | 0.00969848 |
| AREG | amphiregulin | 0.00969561 |
| MAP7 | microtubule-associated protein 7 | 0.00925474 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.00919205 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00872089 |
| VEGFC | vascular endothelial growth factor C | 0.00871626 |
| AJAP1 | adherens junctions associated protein 1 | 0.00861472 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.00847356 |
| MYO1E | myosin IE | 0.00846252 |
| TPI1 | triosephosphate isomerase 1 | 0.00843119 |
| FHIT | fragile histidine triad | 0.00833213 |
| MSN | moesin | 0.00809154 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0076727 |
| IGF2 | insulin-like growth factor 2 | 0.00762373 |
| FAM13A | family with sequence similarity 13, member A | 0.00749091 |
| CENPF | centromere protein F, 350/400kDa | 0.00740537 |
| CAVIN1 | caveolae associated protein 1 | 0.00736578 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.00729692 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00727965 |
| IRS2 | insulin receptor substrate 2 | 0.00720951 |
| TBC1D22A | TBC1 domain family, member 22A | 0.00720463 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.00706198 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00701735 |
| HOMER1 | homer scaffolding protein 1 | 0.00701592 |
| FNIP1 | folliculin interacting protein 1 | 0.00694697 |
| PRKD1 | protein kinase D1 | 0.00672282 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.00670952 |
| S100A11 | S100 calcium binding protein A11 | 0.00657109 |
| MPZL2 | myelin protein zero-like 2 | 0.00651058 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.00647304 |
| GK | glycerol kinase | 0.00645701 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00616029 |
| WWOX | WW domain containing oxidoreductase | 0.00615865 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0061395 |
| C11ORF58 | chromosome 11 open reading frame 58 | 0.00609316 |
| TMEM164 | transmembrane protein 164 | 0.00594142 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0059389 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0059292 |
| NCKAP5 | NCK-associated protein 5 | 0.00591874 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.00590979 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.00589679 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.00588398 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00575666 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.00572569 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00570381 |
| GOLGB1 | golgin B1 | 0.00568518 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00565591 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00562572 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0056202 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00559223 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.00557623 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.00557293 |
| HMGA2 | high mobility group AT-hook 2 | 0.00554422 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.00546611 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.00543402 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0054256 |
| IRF2BPL | interferon regulatory factor 2 binding protein-like | 0.00540543 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00537508 |
| C12ORF57 | chromosome 12 open reading frame 57 | 0.00536465 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00534723 |
| DISC1 | disrupted in schizophrenia 1 | 0.00534251 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.00531034 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.00528744 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00523859 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00518513 |
| STK17A | serine/threonine kinase 17a | 0.00510922 |
| MIDN | midnolin | 0.00509748 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.00505266 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00504527 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0050408 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.00503282 |
| ENSA | endosulfine alpha | 0.00500447 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.213878 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.200421 |
| TXNRD1 | thioredoxin reductase 1 | -0.162927 |
| UBC | ubiquitin C | -0.0731763 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0564352 |
| ANXA2 | annexin A2 | -0.0527262 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0492874 |
| FTL | ferritin, light polypeptide | -0.0489747 |
| PKM | pyruvate kinase, muscle | -0.0486597 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0468828 |
| NDRG1 | N-myc downstream regulated 1 | -0.0461283 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0450823 |
| LMO7 | LIM domain 7 | -0.0447323 |
| LDHA | lactate dehydrogenase A | -0.0421323 |
| ASPH | aspartate beta-hydroxylase | -0.0416734 |
| OSMR | oncostatin M receptor | -0.0406868 |
| EFNA5 | ephrin-A5 | -0.0386737 |
| RPS27A | ribosomal protein S27a | -0.0375106 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336754 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0326972 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0326597 |
| RAB10 | RAB10, member RAS oncogene family | -0.0321128 |
| ENO1 | enolase 1, (alpha) | -0.0315932 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0313736 |
| CES1 | carboxylesterase 1 | -0.0313702 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0311209 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0306374 |
| CPE | carboxypeptidase E | -0.029301 |
| AHNAK | AHNAK nucleoprotein | -0.0291386 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0290478 |
| PCBP2 | poly(rC) binding protein 2 | -0.0283569 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0278881 |
| TMEM165 | transmembrane protein 165 | -0.0278587 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0262401 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0261187 |
| LAMB3 | laminin, beta 3 | -0.025787 |
| KCMF1 | potassium channel modulatory factor 1 | -0.025428 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0251515 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0248943 |
| PGK1 | phosphoglycerate kinase 1 | -0.0243975 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.024369 |
| USP34 | ubiquitin specific peptidase 34 | -0.0242375 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0240711 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0239349 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0231275 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0227973 |
| TES | testin LIM domain protein | -0.0226996 |
| RNF213 | ring finger protein 213 | -0.0226662 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0224913 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0224707 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0222268 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0222009 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0219241 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0219196 |
| RPL37A | ribosomal protein L37a | -0.0211305 |
| LAMA4 | laminin, alpha 4 | -0.0210176 |
| LAMC2 | laminin, gamma 2 | -0.0209513 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0208488 |
| RPS25 | ribosomal protein S25 | -0.0208339 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0207531 |
| SPAG9 | sperm associated antigen 9 | -0.02063 |
| RPS3 | ribosomal protein S3 | -0.0205793 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0204861 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0204469 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0202507 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0202335 |
| CST3 | cystatin C | -0.0199236 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0198619 |
| SLC38A1 | solute carrier family 38, member 1 | -0.019659 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0195061 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0193902 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0193898 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0192926 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0192146 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0190369 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0189929 |
| RPL31 | ribosomal protein L31 | -0.0189895 |
| CANX | calnexin | -0.0189466 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0185443 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0184274 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0181941 |
| JAK1 | Janus kinase 1 | -0.0181532 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0181214 |
| RPL11 | ribosomal protein L11 | -0.0179439 |
| WDR45B | WD repeat domain 45B | -0.0176695 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0175924 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0175294 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0174353 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0172962 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0172936 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0172752 |
| DSPP | dentin sialophosphoprotein | -0.0172289 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0171632 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0171435 |
| RPL34 | ribosomal protein L34 | -0.0171416 |
| RPS24 | ribosomal protein S24 | -0.0171362 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0170481 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0170294 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0168699 |
| RACK1 | receptor for activated C kinase 1 | -0.0166393 |
