| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.161543 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.128254 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.106622 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0893111 |
| ASPH | aspartate beta-hydroxylase | 0.0851746 |
| NDRG1 | N-myc downstream regulated 1 | 0.0851129 |
| ENO1 | enolase 1, (alpha) | 0.0779987 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0676933 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0648149 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0646377 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0620838 |
| TMSB10 | thymosin beta 10 | 0.0620378 |
| PGK1 | phosphoglycerate kinase 1 | 0.0614476 |
| VIM | vimentin | 0.0576159 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0550586 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0549836 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0540883 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0506255 |
| PKM | pyruvate kinase, muscle | 0.0493572 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.048821 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0485279 |
| CCNI | cyclin I | 0.0460747 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.045156 |
| HELZ | helicase with zinc finger | 0.0449417 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0447914 |
| RPS3 | ribosomal protein S3 | 0.0444075 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444074 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0430795 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 0.042169 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0410241 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0406155 |
| DST | dystonin | 0.0405198 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0396802 |
| PRKCA | protein kinase C, alpha | 0.039458 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0382772 |
| RPS17 | ribosomal protein S17 | 0.0382353 |
| STC1 | stanniocalcin 1 | 0.0379584 |
| RAB10 | RAB10, member RAS oncogene family | 0.0379469 |
| RPL19 | ribosomal protein L19 | 0.0371478 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0360709 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0357817 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0350324 |
| PGM3 | phosphoglucomutase 3 | 0.0347313 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0345341 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.034435 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0337401 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.033616 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0332373 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0328499 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0327331 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0325676 |
| RPL5 | ribosomal protein L5 | 0.0319699 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0317854 |
| UBXN4 | UBX domain protein 4 | 0.0316128 |
| RPS12 | ribosomal protein S12 | 0.0313306 |
| MT2A | metallothionein 2A | 0.0312895 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0311411 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.030814 |
| IRS2 | insulin receptor substrate 2 | 0.0307006 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0306343 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0305604 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0303944 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.030359 |
| EXOC4 | exocyst complex component 4 | 0.0302511 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0301454 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0299768 |
| DTNA | dystrobrevin, alpha | 0.0299549 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0296461 |
| RAD51B | RAD51 paralog B | 0.0294214 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0293034 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.029188 |
| SPAG9 | sperm associated antigen 9 | 0.029104 |
| EFNA5 | ephrin-A5 | 0.0289876 |
| RPL30 | ribosomal protein L30 | 0.0289408 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0288901 |
| FOSL1 | FOS-like antigen 1 | 0.0284815 |
| RDX | radixin | 0.0284797 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0284722 |
| RPS8 | ribosomal protein S8 | 0.0283666 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0283558 |
| RPS6 | ribosomal protein S6 | 0.0281399 |
| XDH | xanthine dehydrogenase | 0.0277559 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0277078 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0276199 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0275495 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0275409 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0274736 |
| RPL32 | ribosomal protein L32 | 0.0273785 |
| RPS27 | ribosomal protein S27 | 0.0272499 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0271732 |
| VMP1 | vacuole membrane protein 1 | 0.0271546 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0271541 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0270686 |
| FNBP1L | formin binding protein 1-like | 0.0268241 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0268056 |
| HDAC4 | histone deacetylase 4 | 0.0264283 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.026238 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0261578 |
| TLK1 | tousled-like kinase 1 | 0.0259423 |
| RPL23 | ribosomal protein L23 | 0.0259272 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.164718 |
| LMO7 | LIM domain 7 | -0.143774 |
| GRB10 | growth factor receptor-bound protein 10 | -0.12911 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.122762 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0859882 |
| ATOSA | atos homolog A | -0.0856782 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0848173 |
| LAMC2 | laminin, gamma 2 | -0.084692 |
| MYO1E | myosin IE | -0.0750247 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.071591 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0691282 |
| SVIL | supervillin | -0.0671356 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0621114 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0603447 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0600658 |
| LAMB3 | laminin, beta 3 | -0.0568892 |
| ANXA2 | annexin A2 | -0.0556626 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0544073 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0525752 |
| MUC16 | mucin 16, cell surface associated | -0.051194 |
| RBM47 | RNA binding motif protein 47 | -0.0488555 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0472719 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0450805 |
| TJP2 | tight junction protein 2 | -0.0442678 |
| CMIP | c-Maf inducing protein | -0.0432691 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0432646 |
| ZNF217 | zinc finger protein 217 | -0.0432559 |
| PARD3 | par-3 family cell polarity regulator | -0.0429553 |
| MYO6 | myosin VI | -0.0418784 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0418576 |
| FOXO3 | forkhead box O3 | -0.0400197 |
| AHNAK | AHNAK nucleoprotein | -0.0397241 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0393495 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0386873 |
| STEAP4 | STEAP family member 4 | -0.0385988 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0382182 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0381102 |
| PRELID2 | PRELI domain containing 2 | -0.0375505 |
| ABHD17C | abhydrolase domain containing 17C | -0.0372131 |
| FN1 | fibronectin 1 | -0.0368011 |
| SGMS2 | sphingomyelin synthase 2 | -0.0364911 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.03649 |
| MYO5B | myosin VB | -0.0361906 |
| GLUL | glutamate-ammonia ligase | -0.0360905 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0360344 |
| CNKSR3 | CNKSR family member 3 | -0.0357584 |
| RESF1 | retroelement silencing factor 1 | -0.035299 |
| TJP1 | tight junction protein 1 | -0.0352879 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0342211 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0337205 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0334347 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0334239 |
| TAOK3 | TAO kinase 3 | -0.0334239 |
| JUP | junction plakoglobin | -0.0334195 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0332006 |
| FOXO1 | forkhead box O1 | -0.0327937 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.032279 |
| NHSL1 | NHS-like 1 | -0.0319405 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0318752 |
| FBXO34 | F-box protein 34 | -0.0318229 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.031687 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0314798 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0313167 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | -0.031138 |
| TC2N | tandem C2 domains, nuclear | -0.0310843 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0310655 |
| GOLGA4 | golgin A4 | -0.0309056 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0308382 |
| CLDN4 | claudin 4 | -0.0306962 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.030446 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0304165 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0302751 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0302049 |
| RCOR1 | REST corepressor 1 | -0.0293881 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0293358 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0293108 |
| YME1L1 | YME1-like 1 ATPase | -0.0291313 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0291012 |
| EGFR | epidermal growth factor receptor | -0.0290851 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0288894 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0286763 |
| ETV6 | ets variant 6 | -0.0276684 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0274585 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0273009 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.027181 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0270323 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0270246 |
| OCLN | occludin | -0.0269622 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0268049 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0267283 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0261218 |
| GPATCH8 | G patch domain containing 8 | -0.0258142 |
| SETX | senataxin | -0.0257717 |
| PDE10A | phosphodiesterase 10A | -0.0253493 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0253088 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0250552 |
| AK1 | adenylate kinase 1 | -0.0250219 |
| VGF | VGF nerve growth factor inducible | -0.0250144 |
| CTBP2 | C-terminal binding protein 2 | -0.0249994 |
| PALLD | palladin, cytoskeletal associated protein | -0.0246605 |
