| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.173122 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.125433 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.105981 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0928467 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0846387 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0605223 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.055768 |
| LSAMP | limbic system-associated membrane protein | 0.0553712 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0493652 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0449099 |
| NBEAL1 | neurobeachin-like 1 | 0.044108 |
| PRELID2 | PRELI domain containing 2 | 0.0441067 |
| RPS6 | ribosomal protein S6 | 0.0429175 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0419707 |
| VIM | vimentin | 0.0415222 |
| AUTS2 | autism susceptibility candidate 2 | 0.0411534 |
| MCL1 | myeloid cell leukemia 1 | 0.0408191 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0388989 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0385885 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0380327 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0359071 |
| XYLT1 | xylosyltransferase I | 0.0347416 |
| RAD51B | RAD51 paralog B | 0.0346064 |
| FNIP1 | folliculin interacting protein 1 | 0.0334518 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0329147 |
| SQSTM1 | sequestosome 1 | 0.0324817 |
| CTBP2 | C-terminal binding protein 2 | 0.0324694 |
| CDH13 | cadherin 13 | 0.0322422 |
| TENM2 | teneurin transmembrane protein 2 | 0.0319823 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0316981 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0314621 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.03142 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0308974 |
| MAP7 | microtubule-associated protein 7 | 0.0304735 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0298647 |
| DENND1A | DENN/MADD domain containing 1A | 0.0298296 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0298178 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0292524 |
| NDRG1 | N-myc downstream regulated 1 | 0.029155 |
| CHL1 | cell adhesion molecule L1-like | 0.0289785 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0289741 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0283427 |
| NRXN3 | neurexin 3 | 0.0282744 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0282377 |
| RPS12 | ribosomal protein S12 | 0.0281886 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0281321 |
| ENO1 | enolase 1, (alpha) | 0.0279268 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.027829 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0277299 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.02761 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0275581 |
| IL6 | interleukin 6 | 0.0273922 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0273676 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0271609 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0269199 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.026839 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0266876 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0264341 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0263592 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0260706 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0257636 |
| DNER | delta/notch-like EGF repeat containing | 0.0252206 |
| TPM3 | tropomyosin 3 | 0.0252162 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249175 |
| PKM | pyruvate kinase, muscle | 0.0245163 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0244716 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0244544 |
| FAM107B | family with sequence similarity 107, member B | 0.0242093 |
| SMAD2 | SMAD family member 2 | 0.0238835 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0238439 |
| FAM13A | family with sequence similarity 13, member A | 0.0236015 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0232716 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0231778 |
| FMNL2 | formin-like 2 | 0.0231661 |
| GLRX | glutaredoxin (thioltransferase) | 0.0228921 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0227071 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0222271 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0220951 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217846 |
| CANX | calnexin | 0.0210997 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0209586 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0209059 |
| RPS19 | ribosomal protein S19 | 0.0208492 |
| STC1 | stanniocalcin 1 | 0.0205501 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0205273 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0205089 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0203134 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0199783 |
| LMNA | lamin A/C | 0.0197081 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0196767 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0196336 |
| SVIL | supervillin | 0.0195672 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0195304 |
| UBC | ubiquitin C | 0.019529 |
| RORA | RAR-related orphan receptor A | 0.0194665 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0194641 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0192904 |
| SPAG9 | sperm associated antigen 9 | 0.0192888 |
| PTMA | prothymosin, alpha | 0.0190998 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0189757 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.191826 |
| GDA | guanine deaminase | -0.16431 |
| TXNRD1 | thioredoxin reductase 1 | -0.112865 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.10453 |
| EFNA5 | ephrin-A5 | -0.0975348 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0881473 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0852621 |
| SMYD3 | SET and MYND domain containing 3 | -0.0771675 |
| NEK7 | NIMA-related kinase 7 | -0.0762074 |
| ASPH | aspartate beta-hydroxylase | -0.075299 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.06575 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0576055 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0570988 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.055981 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0547373 |
| NRCAM | neuronal cell adhesion molecule | -0.0520076 |
| TNPO1 | transportin 1 | -0.0509016 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0499533 |
| ENAH | enabled homolog (Drosophila) | -0.0492682 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0475852 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0450065 |
| COL5A2 | collagen, type V, alpha 2 | -0.0431413 |
| RTN1 | reticulon 1 | -0.0422291 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0392459 |
| CTSC | cathepsin C | -0.0384931 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0379209 |
| RTN4 | reticulon 4 | -0.0370882 |
| VCL | vinculin | -0.036602 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.036164 |
| DST | dystonin | -0.0361285 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0347174 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0342269 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0339033 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0326317 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0323337 |
| OSMR | oncostatin M receptor | -0.0319495 |
| PHF20 | PHD finger protein 20 | -0.031254 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0309513 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0305955 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.030446 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0303017 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0300494 |
| KYNU | kynureninase | -0.0295969 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0287384 |
| NF1 | neurofibromin 1 | -0.0286775 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0286253 |
| RBM39 | RNA binding motif protein 39 | -0.0285242 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0284923 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0284438 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.028186 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0279463 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0270715 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0270663 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0269898 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0267612 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0262028 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0261709 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0260768 |
| MFF | mitochondrial fission factor | -0.0256916 |
| AOPEP | aminopeptidase O (putative) | -0.0255989 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0250882 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0250083 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0249696 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249184 |
| OGA | O-GlcNAcase | -0.0248779 |
| CD109 | CD109 molecule | -0.024586 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0241555 |
| CENPF | centromere protein F, 350/400kDa | -0.0240793 |
| WDR43 | WD repeat domain 43 | -0.0240473 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0238165 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0236783 |
| PALLD | palladin, cytoskeletal associated protein | -0.0235614 |
| MKI67 | marker of proliferation Ki-67 | -0.0232871 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0231005 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0230267 |
| RAB10 | RAB10, member RAS oncogene family | -0.0228663 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0228187 |
| LAMA1 | laminin, alpha 1 | -0.0227707 |
| TUSC3 | tumor suppressor candidate 3 | -0.0225734 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.022293 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0222792 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0220543 |
| PTGR1 | prostaglandin reductase 1 | -0.0215116 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0213886 |
| GRAMD1B | GRAM domain containing 1B | -0.0213375 |
| PHF14 | PHD finger protein 14 | -0.0212591 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0212433 |
| ACTG1 | actin gamma 1 | -0.0207852 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.020416 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0202303 |
| POU2F1 | POU class 2 homeobox 1 | -0.0202166 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0199613 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0199588 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.0199282 |
| DPYD | dihydropyrimidine dehydrogenase | -0.019901 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0194179 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0194125 |
| MYOF | myoferlin | -0.0193461 |
| KIF21A | kinesin family member 21A | -0.0193312 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0192956 |
