| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.164731 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.157629 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.120529 |
| PDE10A | phosphodiesterase 10A | 0.100345 |
| LDHA | lactate dehydrogenase A | 0.0980986 |
| EFNA5 | ephrin-A5 | 0.0932939 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0918171 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0916997 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0905629 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0866951 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0849745 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0817742 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0807836 |
| WWOX | WW domain containing oxidoreductase | 0.0750977 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0739725 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0719575 |
| KMT5B | lysine methyltransferase 5B | 0.0659352 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0630384 |
| LSAMP | limbic system-associated membrane protein | 0.0607297 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0588275 |
| RPL36 | ribosomal protein L36 | 0.0585757 |
| RPL11 | ribosomal protein L11 | 0.0578702 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0565962 |
| ACTN4 | actinin, alpha 4 | 0.0556923 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0550795 |
| HDLBP | high density lipoprotein binding protein | 0.0543202 |
| TXNRD1 | thioredoxin reductase 1 | 0.0537339 |
| PDZD8 | PDZ domain containing 8 | 0.0533182 |
| ZNF292 | zinc finger protein 292 | 0.053199 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0528749 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0528553 |
| HDAC4 | histone deacetylase 4 | 0.0523077 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0518065 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0512286 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.051112 |
| PGK1 | phosphoglycerate kinase 1 | 0.0504679 |
| CREBBP | CREB binding protein | 0.0503806 |
| RPL12 | ribosomal protein L12 | 0.050073 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0497815 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.049684 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0490063 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0489479 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0488961 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0479998 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0479696 |
| RUNX1 | runt-related transcription factor 1 | 0.0476609 |
| CD109 | CD109 molecule | 0.0472169 |
| SPAG9 | sperm associated antigen 9 | 0.0469237 |
| PDE8A | phosphodiesterase 8A | 0.0458266 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0453308 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0447562 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0447372 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0446534 |
| RPS12 | ribosomal protein S12 | 0.044371 |
| RPL26 | ribosomal protein L26 | 0.0438462 |
| TPR | translocated promoter region, nuclear basket protein | 0.0434815 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0432186 |
| ZNF638 | zinc finger protein 638 | 0.041308 |
| MYO1E | myosin IE | 0.0411456 |
| USP34 | ubiquitin specific peptidase 34 | 0.0398876 |
| RPS13 | ribosomal protein S13 | 0.0397461 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0394403 |
| ATXN2 | ataxin 2 | 0.0393732 |
| RPS25 | ribosomal protein S25 | 0.0389695 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0384888 |
| NBAS | neuroblastoma amplified sequence | 0.0382571 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0380572 |
| RPL23 | ribosomal protein L23 | 0.037162 |
| SETD5 | SET domain containing 5 | 0.0371165 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0369583 |
| FAM168A | family with sequence similarity 168, member A | 0.0369175 |
| MT2A | metallothionein 2A | 0.0366549 |
| THOC2 | THO complex 2 | 0.0357869 |
| RPL19 | ribosomal protein L19 | 0.0356379 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0354187 |
| JMJD1C | jumonji domain containing 1C | 0.0350786 |
| VCL | vinculin | 0.0340884 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0340198 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0330634 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0328482 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0318465 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.03097 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0290845 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0288671 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0285951 |
| TMSB10 | thymosin beta 10 | 0.0276776 |
| PKM | pyruvate kinase, muscle | 0.0275349 |
| RPL38 | ribosomal protein L38 | 0.0270731 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0268614 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0264326 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0261219 |
| RPS29 | ribosomal protein S29 | 0.0256581 |
| RPL15 | ribosomal protein L15 | 0.0256301 |
| DTNA | dystrobrevin, alpha | 0.0255466 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0251417 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0246033 |
| RPS19 | ribosomal protein S19 | 0.0240873 |
| EGFR | epidermal growth factor receptor | 0.0240767 |
| RPS27 | ribosomal protein S27 | 0.0240101 |
| RPS23 | ribosomal protein S23 | 0.0234891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.156224 |
| FN1 | fibronectin 1 | -0.151924 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.146165 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.123077 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.112583 |
| FNDC3B | fibronectin type III domain containing 3B | -0.106327 |
| PRKCA | protein kinase C, alpha | -0.102938 |
| VIM | vimentin | -0.100812 |
| VMP1 | vacuole membrane protein 1 | -0.0989708 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0987799 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0928676 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0900823 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0839592 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0831413 |
| IGF2 | insulin-like growth factor 2 | -0.0815012 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0796116 |
| HELZ | helicase with zinc finger | -0.0793606 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.079157 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0784099 |
| RORA | RAR-related orphan receptor A | -0.0773283 |
| PTK2 | protein tyrosine kinase 2 | -0.0766128 |
| FLNB | filamin B, beta | -0.0760017 |
| RAB10 | RAB10, member RAS oncogene family | -0.0741633 |
| GOLGB1 | golgin B1 | -0.0738053 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.070987 |
| NFIA | nuclear factor I/A | -0.0693074 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0641344 |
| FMNL2 | formin-like 2 | -0.0628764 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0619328 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0610138 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0590623 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0587821 |
| CANX | calnexin | -0.0562125 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0558829 |
| MATR3 | matrin 3 | -0.055598 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0542458 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0537704 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0527735 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0524012 |
| FAM13A | family with sequence similarity 13, member A | -0.0503883 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0490085 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0482277 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0456319 |
| RPL37A | ribosomal protein L37a | -0.0447495 |
| ACTG1 | actin gamma 1 | -0.0446936 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0428607 |
| MED13L | mediator complex subunit 13-like | -0.0422021 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0416677 |
| TFG | TRK-fused gene | -0.0412544 |
| RAD51B | RAD51 paralog B | -0.0408594 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0401367 |
| RPL7 | ribosomal protein L7 | -0.0389547 |
| PTMA | prothymosin, alpha | -0.0389411 |
| ASPH | aspartate beta-hydroxylase | -0.0388986 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0385795 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0365526 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0341975 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0331487 |
| TENM3 | teneurin transmembrane protein 3 | -0.0313711 |
| RSF1 | remodeling and spacing factor 1 | -0.02985 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0293142 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0291531 |
| ENO1 | enolase 1, (alpha) | -0.0285368 |
| TPD52 | tumor protein D52 | -0.0285198 |
| PARD3 | par-3 family cell polarity regulator | -0.0284532 |
| OGA | O-GlcNAcase | -0.0283712 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0278877 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0278647 |
| SMYD3 | SET and MYND domain containing 3 | -0.0277196 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0275286 |
| AHNAK | AHNAK nucleoprotein | -0.0274465 |
| GOLGA4 | golgin A4 | -0.0269702 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.026681 |
| RPL31 | ribosomal protein L31 | -0.0259935 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0255338 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0252251 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0247207 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0218453 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0216638 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0210177 |
| POTEF | POTE ankyrin domain family, member F | -0.0209273 |
| RBM39 | RNA binding motif protein 39 | -0.0202233 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0201349 |
| RPS8 | ribosomal protein S8 | -0.0190868 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.018736 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.018118 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0173574 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0171896 |
| EXOC6B | exocyst complex component 6B | -0.0168105 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.015925 |
| RPL5 | ribosomal protein L5 | -0.0159111 |
| MYOF | myoferlin | -0.0144523 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0136422 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.013277 |
| B2M | beta-2-microglobulin | -0.0131145 |
| RPS6 | ribosomal protein S6 | -0.0122995 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0118856 |
| RPS21 | ribosomal protein S21 | -0.0116229 |
| SBF2 | SET binding factor 2 | -0.0115859 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0115467 |
