| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Celecoxib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | 0.0848951 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0635839 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0573766 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0447164 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0441232 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0353975 |
| DST | dystonin | 0.0346705 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0343721 |
| PEG10 | paternally expressed 10 | 0.0316104 |
| METAP2 | methionyl aminopeptidase 2 | 0.0298971 |
| STAG2 | stromal antigen 2 | 0.0293839 |
| MED13L | mediator complex subunit 13-like | 0.0281198 |
| NTM | neurotrimin | 0.028062 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0279477 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0265445 |
| CFL2 | cofilin 2 (muscle) | 0.0263458 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0263445 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0263329 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0261319 |
| NCAM2 | neural cell adhesion molecule 2 | 0.025121 |
| IGF2 | insulin-like growth factor 2 | 0.0246263 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0245775 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0244454 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0238413 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0230128 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0223212 |
| TCF12 | transcription factor 12 | 0.0219454 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0214142 |
| DENND4A | DENN/MADD domain containing 4A | 0.0213432 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.020656 |
| CCN2 | cellular communication network factor 2 | 0.0201943 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0200916 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0199602 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0199081 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0196467 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0194911 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.019469 |
| MEF2C | myocyte enhancer factor 2C | 0.0194667 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0192109 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0190513 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.018821 |
| PCM1 | pericentriolar material 1 | 0.0188191 |
| TMSB4X | thymosin beta 4, X-linked | 0.0186568 |
| SVIL | supervillin | 0.0184544 |
| TCF20 | transcription factor 20 (AR1) | 0.018453 |
| XPO1 | exportin 1 | 0.0179421 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0175593 |
| CDC42 | cell division cycle 42 | 0.0175347 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0171327 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0169663 |
| MAGT1 | magnesium transporter 1 | 0.0169432 |
| CNTN6 | contactin 6 | 0.0168809 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0168117 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0168107 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0167671 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0167589 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0167212 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0167018 |
| MCM9 | minichromosome maintenance complex component 9 | 0.016647 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.016627 |
| OLA1 | Obg-like ATPase 1 | 0.0166149 |
| BNC2 | basonuclin 2 | 0.0165044 |
| UTRN | utrophin | 0.0164227 |
| PCDH18 | protocadherin 18 | 0.0163993 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0163355 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0163073 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0162945 |
| TJP1 | tight junction protein 1 | 0.0162734 |
| SET | SET nuclear proto-oncogene | 0.0162386 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0161808 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0161754 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0161735 |
| TFG | TRK-fused gene | 0.0161598 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0158836 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0156529 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0155448 |
| RCOR3 | REST corepressor 3 | 0.0155321 |
| RAB11A | RAB11A, member RAS oncogene family | 0.0155213 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0155199 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0154626 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0151937 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0149707 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0148645 |
| ULK4 | unc-51 like kinase 4 | 0.0148005 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.0146767 |
| HYOU1 | hypoxia up-regulated 1 | 0.0146088 |
| WWC2 | WW and C2 domain containing 2 | 0.0145831 |
| GPHN | gephyrin | 0.0144124 |
| CREBBP | CREB binding protein | 0.0143516 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0143326 |
| C7ORF57 | chromosome 7 open reading frame 57 | 0.0141363 |
| TENM3 | teneurin transmembrane protein 3 | 0.0140483 |
| ZNF644 | zinc finger protein 644 | 0.0138413 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0137925 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.0137444 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0137411 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 0.0136454 |
| AHNAK | AHNAK nucleoprotein | 0.0136434 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0136225 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0135384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0797862 |
| VIM | vimentin | -0.0728074 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.064078 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0626447 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0623164 |
| GPC3 | glypican 3 | -0.0600277 |
| RPS16 | ribosomal protein S16 | -0.0574512 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0558333 |
| RPS8 | ribosomal protein S8 | -0.0558148 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0527935 |
| PTMA | prothymosin, alpha | -0.0512797 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0506582 |
| RPL37A | ribosomal protein L37a | -0.0483755 |
| RPL26 | ribosomal protein L26 | -0.0473522 |
| RPLP1 | ribosomal protein, large, P1 | -0.0461025 |
| RPS12 | ribosomal protein S12 | -0.0461005 |
| GNAS | GNAS complex locus | -0.0433372 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0427623 |
| RPL35A | ribosomal protein L35a | -0.0425125 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0414994 |
| RPL12 | ribosomal protein L12 | -0.0393713 |
| TMSB10 | thymosin beta 10 | -0.0389206 |
| CENPF | centromere protein F, 350/400kDa | -0.038 |
| RPL31 | ribosomal protein L31 | -0.0378753 |
| RPS3 | ribosomal protein S3 | -0.0375581 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0374424 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0364137 |
| RPL11 | ribosomal protein L11 | -0.0353996 |
| ENAH | enabled homolog (Drosophila) | -0.0345956 |
| PHIP | pleckstrin homology domain interacting protein | -0.033208 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0330582 |
| UPP1 | uridine phosphorylase 1 | -0.0328506 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0322231 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0321039 |
| RPL23 | ribosomal protein L23 | -0.0316649 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0314256 |
| RPS13 | ribosomal protein S13 | -0.0311991 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0307163 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0306169 |
| TPR | translocated promoter region, nuclear basket protein | -0.0302774 |
| CALR | calreticulin | -0.029966 |
| RPLP0 | ribosomal protein, large, P0 | -0.0298588 |
| RPS6 | ribosomal protein S6 | -0.0295529 |
| RACK1 | receptor for activated C kinase 1 | -0.0295414 |
| ATXN2 | ataxin 2 | -0.0293763 |
| SRP54 | signal recognition particle 54kDa | -0.0291146 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0285549 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0280813 |
| MT2A | metallothionein 2A | -0.0279789 |
| FUS | FUS RNA binding protein | -0.0278799 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0276464 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0275735 |
| FST | follistatin | -0.0275427 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0274383 |
| RPS29 | ribosomal protein S29 | -0.0273219 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0267347 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0265725 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0262353 |
| LDHA | lactate dehydrogenase A | -0.0261303 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0259072 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0257607 |
| FBL | fibrillarin | -0.0256643 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0247712 |
| CEP350 | centrosomal protein 350kDa | -0.0246583 |
| PRTG | protogenin | -0.024529 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0244792 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0244236 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0243895 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0243434 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0241367 |
| THOC2 | THO complex 2 | -0.0241137 |
| PLD3 | phospholipase D family, member 3 | -0.0240213 |
| TMEM165 | transmembrane protein 165 | -0.0239805 |
| RFPL4B | ret finger protein-like 4B | -0.0237755 |
| FN1 | fibronectin 1 | -0.0237501 |
| ZNF292 | zinc finger protein 292 | -0.023723 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0236385 |
| SERF2 | small EDRK-rich factor 2 | -0.0236022 |
| RPS27A | ribosomal protein S27a | -0.0233844 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0232776 |
| RPS19 | ribosomal protein S19 | -0.023237 |
| FBXO11 | F-box protein 11 | -0.0232127 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0231489 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0231392 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0230639 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0228093 |
| SNX6 | sorting nexin 6 | -0.0227103 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0226102 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0225734 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.022505 |
| RPL36 | ribosomal protein L36 | -0.0222833 |
| RBM39 | RNA binding motif protein 39 | -0.022162 |
| RPL5 | ribosomal protein L5 | -0.022131 |
| PCDH17 | protocadherin 17 | -0.0220529 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0220432 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0219903 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0219464 |
| STMN1 | stathmin 1 | -0.0218504 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.021786 |
| TPX2 | TPX2, microtubule-associated | -0.0217144 |
