| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Celecoxib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Celecoxib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.180008 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.131348 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.127247 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0954083 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0681804 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0679498 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0662557 |
| PRELID2 | PRELI domain containing 2 | 0.0608442 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0526137 |
| HDLBP | high density lipoprotein binding protein | 0.0514973 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0504134 |
| B2M | beta-2-microglobulin | 0.0500303 |
| SEC24D | SEC24 family member D | 0.0471328 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0465464 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0434478 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0430161 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0421057 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0419233 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0411474 |
| PTGES2 | prostaglandin E synthase 2 | 0.0408497 |
| KYNU | kynureninase | 0.0404385 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0403227 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0399265 |
| EGFR | epidermal growth factor receptor | 0.0391859 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0390183 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0389787 |
| FNIP1 | folliculin interacting protein 1 | 0.0388659 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0388216 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0383459 |
| SON | SON DNA binding protein | 0.03791 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0374607 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.037349 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0371635 |
| ANLN | anillin, actin binding protein | 0.0364323 |
| FNDC3A | fibronectin type III domain containing 3A | 0.036146 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0359566 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0357563 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0352691 |
| LOXL2 | lysyl oxidase-like 2 | 0.0349681 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0330261 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326108 |
| CCDC14 | coiled-coil domain containing 14 | 0.0318596 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0318049 |
| MYOF | myoferlin | 0.0317164 |
| MAGT1 | magnesium transporter 1 | 0.0312781 |
| MKI67 | marker of proliferation Ki-67 | 0.0310179 |
| TPM3 | tropomyosin 3 | 0.0308686 |
| NRXN3 | neurexin 3 | 0.030569 |
| IL6ST | interleukin 6 signal transducer | 0.030444 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0304002 |
| CDH13 | cadherin 13 | 0.0300411 |
| XPO1 | exportin 1 | 0.0298487 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0296973 |
| FRMD6 | FERM domain containing 6 | 0.0296918 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0293908 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0289124 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0287947 |
| NBAS | neuroblastoma amplified sequence | 0.0287371 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0286547 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0278434 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.027609 |
| CALR | calreticulin | 0.0275801 |
| FMNL2 | formin-like 2 | 0.0271864 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0269817 |
| ITGAV | integrin, alpha V | 0.026823 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0267027 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0264555 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0262935 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0255232 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0252224 |
| FN1 | fibronectin 1 | 0.0250771 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.024998 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0243416 |
| MYLK | myosin light chain kinase | 0.0243405 |
| RORA | RAR-related orphan receptor A | 0.0241908 |
| RAB14 | RAB14, member RAS oncogene family | 0.0241736 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0240784 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0239152 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0238236 |
| CENPE | centromere protein E, 312kDa | 0.0235793 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0235362 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0235007 |
| GOLGB1 | golgin B1 | 0.0232076 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0231971 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0231085 |
| STAG2 | stromal antigen 2 | 0.0230342 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0228998 |
| ANXA6 | annexin A6 | 0.02276 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0227419 |
| NKTR | natural killer cell triggering receptor | 0.0226538 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0226474 |
| PLAUR | plasminogen activator, urokinase receptor | 0.022505 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0223806 |
| MSN | moesin | 0.0223611 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0222612 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0219371 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0218795 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0217543 |
| COL5A1 | collagen, type V, alpha 1 | 0.0215206 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0215137 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.145453 |
| TMSB10 | thymosin beta 10 | -0.132617 |
| VIM | vimentin | -0.124322 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.092175 |
| COL1A1 | collagen, type I, alpha 1 | -0.0728537 |
| FTL | ferritin, light polypeptide | -0.0695501 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0650607 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0622871 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.056898 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0542856 |
| COL1A2 | collagen, type I, alpha 2 | -0.053994 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0528101 |
| MT1X | metallothionein 1X | -0.0507764 |
| PRSS23 | protease, serine, 23 | -0.0493932 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0477411 |
| RPL37A | ribosomal protein L37a | -0.0441607 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0406015 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0392782 |
| RRBP1 | ribosome binding protein 1 | -0.0386576 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0385613 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0369712 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0365883 |
| CALD1 | caldesmon 1 | -0.0364456 |
| HIP1 | huntingtin interacting protein 1 | -0.0362922 |
| STC2 | stanniocalcin 2 | -0.0362775 |
| CADM1 | cell adhesion molecule 1 | -0.0361412 |
| H3-3B | H3.3 histone B | -0.0356042 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0352694 |
| HLA-B | major histocompatibility complex, class I, B | -0.0347044 |
| KAZN | kazrin, periplakin interacting protein | -0.0346798 |
| ANXA2 | annexin A2 | -0.0342426 |
| PDE10A | phosphodiesterase 10A | -0.0340591 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.033 |
| ADM | adrenomedullin | -0.0328946 |
| ENO1 | enolase 1, (alpha) | -0.0327182 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.031919 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0317364 |
| CD99 | CD99 molecule | -0.0315087 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0314664 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0310796 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0309013 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0305987 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0301948 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0301204 |
| OGA | O-GlcNAcase | -0.0300612 |
| TPM4 | tropomyosin 4 | -0.0300461 |
| GNAS | GNAS complex locus | -0.0300409 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0293204 |
| EFNA5 | ephrin-A5 | -0.0293112 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0291397 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0290524 |
| RPL35A | ribosomal protein L35a | -0.0289251 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0287645 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0285878 |
| ACTG1 | actin gamma 1 | -0.0277135 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0276879 |
| RBM25 | RNA binding motif protein 25 | -0.0272146 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0271635 |
| RNF145 | ring finger protein 145 | -0.0270584 |
| S100A6 | S100 calcium binding protein A6 | -0.0267661 |
| ARF4 | ADP-ribosylation factor 4 | -0.0264793 |
| RPS25 | ribosomal protein S25 | -0.0260865 |
| RPS23 | ribosomal protein S23 | -0.0260347 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.025687 |
| TPI1 | triosephosphate isomerase 1 | -0.0254931 |
| RTN4 | reticulon 4 | -0.0253524 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0253037 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.024862 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0247546 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0247329 |
| POMP | proteasome maturation protein | -0.0245615 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0244373 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0242102 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0241889 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0238927 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0238629 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0238451 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0237501 |
| SYCP2 | synaptonemal complex protein 2 | -0.023713 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0236966 |
| RPS12 | ribosomal protein S12 | -0.023291 |
| RPL23 | ribosomal protein L23 | -0.0230318 |
| IKBIP | IKBKB interacting protein | -0.0226459 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0226404 |
| RAB27A | RAB27A, member RAS oncogene family | -0.0226368 |
| MED13L | mediator complex subunit 13-like | -0.0225945 |
| TNS3 | tensin 3 | -0.0225432 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0225297 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0224396 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221188 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0220836 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0220415 |
| LMNA | lamin A/C | -0.0219306 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0219106 |
| EP300 | E1A binding protein p300 | -0.0218852 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0217295 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0217204 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0216655 |
| CDK6 | cyclin-dependent kinase 6 | -0.0215266 |
| CLMP | CXADR-like membrane protein | -0.0215019 |
