Cell cycle Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. (Gene Ontology, GO_0007049)
External Link https://www.kegg.jp/entry/hsa04110
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Genes

157 proteins participating in the Cell cycle pathway from the KEGG Pathways 2026 dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC13 anaphase promoting complex subunit 13
ANAPC15 anaphase promoting complex subunit 15
ANAPC16 anaphase promoting complex subunit 16
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ATM ATM serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
AURKB aurora kinase B
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNB3 cyclin B3
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNH cyclin H
CDC14A cell division cycle 14A
CDC14C cell division cycle 14C
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDC7 cell division cycle 7
CDCA5 cell division cycle associated 5
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDPF1 cysteine-rich, DPF motif domain containing 1
CDT1 chromatin licensing and DNA replication factor 1
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CREBBP CREB binding protein
CUL1 cullin 1
DBF4 DBF4 zinc finger
DBF4B DBF4 zinc finger B
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
EP300 E1A binding protein p300
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FBXO5 F-box protein 5
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC8 histone deacetylase 8
KNL1 kinetochore scaffold 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAU2 MAU2 sister chromatid cohesion factor
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTBP MDM2 binding protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDC80 NDC80 kinetochore complex component
NIPBL Nipped-B homolog (Drosophila)
ORC3 origin recognition complex, subunit 3
ORC4 origin recognition complex, subunit 4
ORC5 origin recognition complex, subunit 5
ORC6 origin recognition complex, subunit 6
PCNA proliferating cell nuclear antigen
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLK1 polo-like kinase 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTTG1 pituitary tumor-transforming 1
PTTG2 pituitary tumor-transforming 2
RAD21 RAD21 homolog (S. pombe)
RB1 retinoblastoma 1
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RBX1 ring-box 1, E3 ubiquitin protein ligase
REXO2 RNA exonuclease 2
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SGO1 shugoshin 1
SKP1 S-phase kinase-associated protein 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMC1A structural maintenance of chromosomes 1A
SMC1B structural maintenance of chromosomes 1B
SMC3 structural maintenance of chromosomes 3
STAG2 stromal antigen 2
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TICRR TOPBP1-interacting checkpoint and replication regulator
TP53 tumor protein p53
TRIP13 thyroid hormone receptor interactor 13
TTK TTK protein kinase
UXT ubiquitously-expressed, prefoldin-like chaperone
WAPL WAPL cohesin release factor
WEE1 WEE1 G2 checkpoint kinase
WEE2 WEE1 homolog 2 (S. pombe)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB17 zinc finger and BTB domain containing 17
ZNF367 zinc finger protein 367