Cellular response to hypoxia Gene Set

Dataset	Reactome Pathways 2014
Category	structural or functional annotations
Type	pathway
Description	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. (Gene Ontology, GO_0071456)
External Link	http://www.reactome.org/PathwayBrowser/#/R-HSA-2262749
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Genes

25 proteins participating in the Cellular response to hypoxia pathway from the Reactome Pathways dataset.

Symbol	Name
ARNT	aryl hydrocarbon receptor nuclear translocator
CA9	carbonic anhydrase IX
CREBBP	CREB binding protein
CUL2	cullin 2
EGLN1	egl-9 family hypoxia-inducible factor 1
EGLN2	egl-9 family hypoxia-inducible factor 2
EGLN3	egl-9 family hypoxia-inducible factor 3
EP300	E1A binding protein p300
EPAS1	endothelial PAS domain protein 1
EPO	erythropoietin
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor
HIF3A	hypoxia inducible factor 3, alpha subunit
RBX1	ring-box 1, E3 ubiquitin protein ligase
RPS27A	ribosomal protein S27a
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1
UBB	ubiquitin B
UBC	ubiquitin C
UBE2D1	ubiquitin-conjugating enzyme E2D 1
UBE2D2	ubiquitin-conjugating enzyme E2D 2
UBE2D3	ubiquitin-conjugating enzyme E2D 3
VEGFA	vascular endothelial growth factor A
VHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase