| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cepharanthine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.142007 |
| SMAD3 | SMAD family member 3 | 0.126383 |
| LMO7 | LIM domain 7 | 0.125815 |
| MACC1 | metastasis associated in colon cancer 1 | 0.101227 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0882914 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0872015 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0852281 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0758626 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0725693 |
| ATP11A | ATPase, class VI, type 11A | 0.0693589 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0661815 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0624296 |
| MLPH | melanophilin | 0.0623173 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0599759 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0586715 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0579045 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0548947 |
| TRIM2 | tripartite motif containing 2 | 0.054831 |
| SPATA13 | spermatogenesis associated 13 | 0.0543079 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0529815 |
| STK24 | serine/threonine kinase 24 | 0.0527904 |
| BCL2L1 | BCL2-like 1 | 0.0523051 |
| MYO1E | myosin IE | 0.0507325 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0499906 |
| ERBIN | erbb2 interacting protein | 0.0487718 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0484759 |
| ATP10B | ATPase, class V, type 10B | 0.0483737 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0479751 |
| TJP2 | tight junction protein 2 | 0.0476179 |
| ASPH | aspartate beta-hydroxylase | 0.0468754 |
| TMC5 | transmembrane channel-like 5 | 0.046698 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0460238 |
| LCN2 | lipocalin 2 | 0.0457368 |
| ETV6 | ets variant 6 | 0.0456137 |
| JUN | jun proto-oncogene | 0.0441569 |
| APP | amyloid beta (A4) precursor protein | 0.0425671 |
| SDC4 | syndecan 4 | 0.0424868 |
| FHL2 | four and a half LIM domains 2 | 0.0417676 |
| DUSP10 | dual specificity phosphatase 10 | 0.0415472 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0394873 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0388461 |
| CTBP2 | C-terminal binding protein 2 | 0.0383644 |
| AREG | amphiregulin | 0.037497 |
| ANXA2 | annexin A2 | 0.037116 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370156 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0364128 |
| EZR | ezrin | 0.0361925 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0361635 |
| EPHB2 | EPH receptor B2 | 0.0360565 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.035826 |
| RNF213 | ring finger protein 213 | 0.035623 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0354862 |
| MSI2 | musashi RNA-binding protein 2 | 0.0341836 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0332596 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0329996 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0328038 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0326477 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0325609 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0325379 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0323 |
| PRELID2 | PRELI domain containing 2 | 0.0317235 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0315926 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0315738 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0314011 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0313153 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0307502 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.030663 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0305047 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.03045 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0303922 |
| HLA-B | major histocompatibility complex, class I, B | 0.0302745 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0302486 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0299461 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0298644 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0295693 |
| SEPTIN9 | septin 9 | 0.0295625 |
| ACTN4 | actinin, alpha 4 | 0.029507 |
| VCL | vinculin | 0.0294453 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0291618 |
| MYO5B | myosin VB | 0.0290094 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0289113 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0285524 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0283543 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0281109 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0276356 |
| ADM | adrenomedullin | 0.027603 |
| KIF13B | kinesin family member 13B | 0.0275622 |
| DOCK1 | dedicator of cytokinesis 1 | 0.027559 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0275541 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0275349 |
| VEGFA | vascular endothelial growth factor A | 0.027445 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0274337 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0273419 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0272538 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.027171 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0269236 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0266247 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0266234 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0265936 |
| PRKCA | protein kinase C, alpha | 0.0264432 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120923 |
| B2M | beta-2-microglobulin | -0.110783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105389 |
| PERP | PERP, TP53 apoptosis effector | -0.0952397 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0866395 |
| LYZ | lysozyme | -0.0771946 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0749396 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.07012 |
| EGR1 | early growth response 1 | -0.068469 |
| RPS6 | ribosomal protein S6 | -0.0684497 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0674042 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0668088 |
| RPLP1 | ribosomal protein, large, P1 | -0.0589536 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0569935 |
| PLSCR2 | phospholipid scramblase 2 | -0.0535018 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0534696 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0525574 |
| XAF1 | XIAP associated factor 1 | -0.0518054 |
| PKM | pyruvate kinase, muscle | -0.0515975 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0495418 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0486924 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0480454 |
| IRF1 | interferon regulatory factor 1 | -0.0475877 |
| RPL34 | ribosomal protein L34 | -0.0455528 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0453067 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0445858 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.044511 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0440842 |
| SP100 | SP100 nuclear antigen | -0.0433419 |
| INTS6 | integrator complex subunit 6 | -0.0430175 |
| DSTN | destrin (actin depolymerizing factor) | -0.0418733 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0396724 |
| CST3 | cystatin C | -0.0390524 |
| S100A10 | S100 calcium binding protein A10 | -0.0389694 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0380805 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0379554 |
| RPL35A | ribosomal protein L35a | -0.0378551 |
| NPSR1 | neuropeptide S receptor 1 | -0.0372996 |
| S100A6 | S100 calcium binding protein A6 | -0.0369681 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0369582 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0368789 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0366706 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0354917 |
| RPL21 | ribosomal protein L21 | -0.035422 |
| RPLP0 | ribosomal protein, large, P0 | -0.0343264 |
| RIGI | RNA sensor RIG-I | -0.0335775 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0335189 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0334943 |
| NUCB2 | nucleobindin 2 | -0.0334537 |
| RPLP2 | ribosomal protein, large, P2 | -0.0332276 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0330668 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0329444 |
| RPS27 | ribosomal protein S27 | -0.0328667 |
| RTN3 | reticulon 3 | -0.0326441 |
| DIAPH3 | diaphanous-related formin 3 | -0.0325706 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0322203 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0320767 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0315728 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0307704 |
| ATF4 | activating transcription factor 4 | -0.0307655 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.030688 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0303702 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0297973 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0296928 |
| ENO1 | enolase 1, (alpha) | -0.0295443 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0291908 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0291311 |
| NDRG1 | N-myc downstream regulated 1 | -0.0290081 |
| EHF | ets homologous factor | -0.0288816 |
| PTMA | prothymosin, alpha | -0.0286036 |
| TRIM25 | tripartite motif containing 25 | -0.0283576 |
| RPS23 | ribosomal protein S23 | -0.0276199 |
| BPTF | bromodomain PHD finger transcription factor | -0.0275153 |
| HMGB1 | high mobility group box 1 | -0.0273535 |
| POTEF | POTE ankyrin domain family, member F | -0.026965 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0267821 |
| RPS8 | ribosomal protein S8 | -0.0265197 |
| LDHA | lactate dehydrogenase A | -0.0262301 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0259542 |
| APOL6 | apolipoprotein L, 6 | -0.0255778 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0255125 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0254371 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0254213 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.025265 |
| RPS19 | ribosomal protein S19 | -0.025175 |
| CTSD | cathepsin D | -0.0250996 |
| SQSTM1 | sequestosome 1 | -0.0250631 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0249116 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0245675 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0244354 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0244022 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0243841 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0240147 |
| MTDH | metadherin | -0.0238305 |
| IRS2 | insulin receptor substrate 2 | -0.0237411 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0236914 |
| RPS28 | ribosomal protein S28 | -0.0235907 |
| CSTB | cystatin B (stefin B) | -0.0235906 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0232327 |
| RPL7 | ribosomal protein L7 | -0.0231967 |