| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.33043 |
| FN1 | fibronectin 1 | 0.235709 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.138574 |
| VEGFA | vascular endothelial growth factor A | 0.138235 |
| CALR | calreticulin | 0.127357 |
| NDRG1 | N-myc downstream regulated 1 | 0.119186 |
| TMSB10 | thymosin beta 10 | 0.0899171 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0835733 |
| MT2A | metallothionein 2A | 0.0696248 |
| PLEC | plectin | 0.0640396 |
| COL7A1 | collagen, type VII, alpha 1 | 0.062211 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0605815 |
| HLA-B | major histocompatibility complex, class I, B | 0.0595223 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0469319 |
| CADM1 | cell adhesion molecule 1 | 0.0442205 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0438079 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0407446 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0395803 |
| RPL35A | ribosomal protein L35a | 0.0379509 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0379462 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0376783 |
| HLA-A | major histocompatibility complex, class I, A | 0.0359088 |
| CDH13 | cadherin 13 | 0.0340992 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0340617 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0329644 |
| FLNA | filamin A, alpha | 0.0325337 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0322012 |
| EGR1 | early growth response 1 | 0.0318317 |
| ACTG1 | actin gamma 1 | 0.0309062 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0301089 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0294171 |
| RND3 | Rho family GTPase 3 | 0.0287371 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0286632 |
| RPL23 | ribosomal protein L23 | 0.0284626 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0278584 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0274866 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0269615 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0266893 |
| RPN1 | ribophorin I | 0.0264294 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0262638 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0253655 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0252837 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0251112 |
| APP | amyloid beta (A4) precursor protein | 0.0241183 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0238626 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0238106 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0235636 |
| FTL | ferritin, light polypeptide | 0.0234405 |
| NAV2 | neuron navigator 2 | 0.023174 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0230392 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022506 |
| BRD2 | bromodomain containing 2 | 0.0223893 |
| ADM | adrenomedullin | 0.0223296 |
| SQSTM1 | sequestosome 1 | 0.0221354 |
| RPL7A | ribosomal protein L7a | 0.0215911 |
| COL5A1 | collagen, type V, alpha 1 | 0.0213499 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0212142 |
| HYOU1 | hypoxia up-regulated 1 | 0.0212012 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0210472 |
| RPL36 | ribosomal protein L36 | 0.0210209 |
| RPS19 | ribosomal protein S19 | 0.0208655 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.020407 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0202916 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0202794 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0202275 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0201789 |
| ITGA11 | integrin, alpha 11 | 0.0195999 |
| HDAC9 | histone deacetylase 9 | 0.0195662 |
| INTS6 | integrator complex subunit 6 | 0.0195178 |
| TGFB1 | transforming growth factor, beta 1 | 0.019476 |
| RPL37A | ribosomal protein L37a | 0.0193609 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0192144 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0189418 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0187307 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0187105 |
| FUS | FUS RNA binding protein | 0.0185865 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0180508 |
| RPL13A | ribosomal protein L13a | 0.0180197 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0179432 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0177974 |
| PMM2 | phosphomannomutase 2 | 0.0175972 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0174544 |
| C1D | C1D nuclear receptor corepressor | 0.0172474 |
| RPL8 | ribosomal protein L8 | 0.017019 |
| CCNL1 | cyclin L1 | 0.0168035 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0164853 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.016482 |
| TNS1 | tensin 1 | 0.016439 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0162527 |
| CTBP2 | C-terminal binding protein 2 | 0.0161557 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.016134 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0160277 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0158453 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0157411 |
| RPS3 | ribosomal protein S3 | 0.0157161 |
| RPL28 | ribosomal protein L28 | 0.0155279 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0154623 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0154562 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0153492 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0151732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.159981 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.135506 |
| COL1A1 | collagen, type I, alpha 1 | -0.131217 |
| COL1A2 | collagen, type I, alpha 2 | -0.123022 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.121357 |
| VIM | vimentin | -0.113095 |
| VCAN | versican | -0.110222 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101255 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0972801 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0971298 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0945595 |
| FBN1 | fibrillin 1 | -0.0809097 |
| STC1 | stanniocalcin 1 | -0.0771201 |
| ATP13A3 | ATPase type 13A3 | -0.0748768 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0747246 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0746266 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0725117 |
| TPM4 | tropomyosin 4 | -0.0687672 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0677323 |
| IL6ST | interleukin 6 signal transducer | -0.0644218 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0635927 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0612455 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0611625 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0596767 |
| LDHA | lactate dehydrogenase A | -0.0572812 |
| DST | dystonin | -0.0570704 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0567052 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0550856 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0549715 |
| CD44 | CD44 molecule (Indian blood group) | -0.0549092 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0543702 |
| GLIS3 | GLIS family zinc finger 3 | -0.054241 |
| HMGA2 | high mobility group AT-hook 2 | -0.0513852 |
| MTSS1 | metastasis suppressor 1 | -0.0502594 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0480029 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0467703 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0467655 |
| ZNF292 | zinc finger protein 292 | -0.0461148 |
| MAP1B | microtubule-associated protein 1B | -0.0457832 |
| CALD1 | caldesmon 1 | -0.0451752 |
| SBF2 | SET binding factor 2 | -0.0447577 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0440239 |
| PRELID2 | PRELI domain containing 2 | -0.0426227 |
| POSTN | periostin, osteoblast specific factor | -0.0421202 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0420049 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.041525 |
| CANX | calnexin | -0.0398384 |
| PDE10A | phosphodiesterase 10A | -0.0397093 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0371049 |
| BBX | bobby sox homolog (Drosophila) | -0.0367953 |
| PGK1 | phosphoglycerate kinase 1 | -0.0353325 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0352171 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0350132 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0346371 |
| CNTN5 | contactin 5 | -0.0346359 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0337586 |
| ARRDC3 | arrestin domain containing 3 | -0.0329314 |
| PKM | pyruvate kinase, muscle | -0.0323643 |
| LOX | lysyl oxidase | -0.0320897 |
| RLF | rearranged L-myc fusion | -0.0318609 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0315576 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0315435 |
| RPS2 | ribosomal protein S2 | -0.0309759 |
| ENO1 | enolase 1, (alpha) | -0.0307236 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0305333 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0305288 |
| ECE1 | endothelin converting enzyme 1 | -0.0304269 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0302402 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0301233 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0295708 |
| ANXA2 | annexin A2 | -0.0293728 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0291839 |
| CLIC4 | chloride intracellular channel 4 | -0.0290529 |
| PTK2 | protein tyrosine kinase 2 | -0.0288549 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0286076 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0285728 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0282592 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0281949 |
| RUNX1 | runt-related transcription factor 1 | -0.027993 |
| GOLGA4 | golgin A4 | -0.0274337 |
| DSTN | destrin (actin depolymerizing factor) | -0.0272758 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0272248 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0271233 |
| NRP1 | neuropilin 1 | -0.0270694 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0268766 |
| FRMD4A | FERM domain containing 4A | -0.0264519 |
| SEPTIN7 | septin 7 | -0.0257389 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0256697 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0253539 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0252227 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0245633 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0243723 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0241083 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0237905 |
| TPM1 | tropomyosin 1 (alpha) | -0.0235683 |
| NKTR | natural killer cell triggering receptor | -0.0235279 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0234238 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0232634 |
| SPAG9 | sperm associated antigen 9 | -0.0232191 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0231888 |
