| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.298723 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.180388 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.174185 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.147275 |
| SVIL | supervillin | 0.12804 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.125309 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.109329 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0854716 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.082216 |
| MT2A | metallothionein 2A | 0.0771496 |
| TNS1 | tensin 1 | 0.0752124 |
| VEGFA | vascular endothelial growth factor A | 0.0709662 |
| PEG3 | paternally expressed 3 | 0.0663596 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0597793 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0597565 |
| NDRG1 | N-myc downstream regulated 1 | 0.0594072 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0587579 |
| SDC4 | syndecan 4 | 0.0565639 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0558774 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0526998 |
| DSPP | dentin sialophosphoprotein | 0.0526056 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0522727 |
| SMAD3 | SMAD family member 3 | 0.0504501 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0499775 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0491001 |
| FAM107B | family with sequence similarity 107, member B | 0.0475684 |
| ATXN1 | ataxin 1 | 0.0455919 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0449196 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0431106 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0429473 |
| KIAA1217 | KIAA1217 | 0.0425537 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.042063 |
| ASPH | aspartate beta-hydroxylase | 0.0415072 |
| FOXP1 | forkhead box P1 | 0.0410806 |
| BCL2L1 | BCL2-like 1 | 0.0408034 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0380646 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0377695 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0377339 |
| ITGB5 | integrin, beta 5 | 0.0370806 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0370647 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0363483 |
| KYNU | kynureninase | 0.0360909 |
| VCL | vinculin | 0.0359495 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0354578 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0352716 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0351886 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0348973 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0346764 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0343629 |
| FLNA | filamin A, alpha | 0.0339207 |
| DIAPH1 | diaphanous-related formin 1 | 0.0338446 |
| ALPK2 | alpha-kinase 2 | 0.0336161 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0334841 |
| ITGAV | integrin, alpha V | 0.0334734 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0325076 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0324816 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0319224 |
| FAT1 | FAT atypical cadherin 1 | 0.0318453 |
| FRMD5 | FERM domain containing 5 | 0.031582 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0313794 |
| ACTG1 | actin gamma 1 | 0.0310807 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0306628 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0306114 |
| DOCK5 | dedicator of cytokinesis 5 | 0.030587 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0302868 |
| DST | dystonin | 0.0297876 |
| PMM2 | phosphomannomutase 2 | 0.0293757 |
| RUNX1 | runt-related transcription factor 1 | 0.0292769 |
| PLEC | plectin | 0.0292267 |
| CTSB | cathepsin B | 0.0282642 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0282444 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0280152 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0277939 |
| JAG1 | jagged 1 | 0.0271543 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0267747 |
| FHL2 | four and a half LIM domains 2 | 0.0264485 |
| FLNB | filamin B, beta | 0.0262176 |
| CLTB | clathrin, light chain B | 0.0255846 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0255569 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0252985 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0252244 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0252057 |
| MYO5B | myosin VB | 0.0251589 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0246664 |
| STC2 | stanniocalcin 2 | 0.0245852 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0241299 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0238421 |
| FAM13A | family with sequence similarity 13, member A | 0.0238394 |
| RPL3 | ribosomal protein L3 | 0.023791 |
| GSE1 | Gse1 coiled-coil protein | 0.023608 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0232592 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0231442 |
| RAD51B | RAD51 paralog B | 0.0230905 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0226984 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.022348 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0223214 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0221641 |
| NABP1 | nucleic acid binding protein 1 | 0.0220659 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0220274 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0220086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.146356 |
| APOA2 | apolipoprotein A-II | -0.134832 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.104982 |
| GPC3 | glypican 3 | -0.102253 |
| RPS6 | ribosomal protein S6 | -0.10016 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.095146 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0938956 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0813313 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0807387 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0802398 |
| CP | ceruloplasmin (ferroxidase) | -0.0774515 |
| A2M | alpha-2-macroglobulin | -0.0772465 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0716161 |
| RPL11 | ribosomal protein L11 | -0.0714828 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0686164 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0677531 |
| RPS8 | ribosomal protein S8 | -0.0676086 |
| EHBP1 | EH domain binding protein 1 | -0.0670922 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0655955 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0612858 |
| RPS24 | ribosomal protein S24 | -0.0606698 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0605313 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0594956 |
| FTL | ferritin, light polypeptide | -0.0575928 |
| RPL34 | ribosomal protein L34 | -0.0552512 |
| LYZ | lysozyme | -0.0529615 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0521895 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0513688 |
| TRIM26 | tripartite motif containing 26 | -0.0509261 |
| RPLP2 | ribosomal protein, large, P2 | -0.0485588 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0472078 |
| C3 | complement component 3 | -0.0460368 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0457638 |
| RPL35A | ribosomal protein L35a | -0.0457173 |
| TMEM123 | transmembrane protein 123 | -0.0449471 |
| RPLP1 | ribosomal protein, large, P1 | -0.0445379 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0431655 |
| RPS13 | ribosomal protein S13 | -0.0431457 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0426076 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0422227 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0414917 |
| PTCHD4 | patched domain containing 4 | -0.0414686 |
| RPS27A | ribosomal protein S27a | -0.0413588 |
| PTMA | prothymosin, alpha | -0.0404823 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0402018 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0393978 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.038887 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0384658 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0381013 |
| SELENOP | selenoprotein P | -0.0381012 |
| RPL37A | ribosomal protein L37a | -0.0374678 |
| RPL31 | ribosomal protein L31 | -0.0370737 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0365157 |
| PARD3 | par-3 family cell polarity regulator | -0.0359144 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0356227 |
| RPS23 | ribosomal protein S23 | -0.0353888 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0353242 |
| PERP | PERP, TP53 apoptosis effector | -0.0348238 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0347918 |
| RACK1 | receptor for activated C kinase 1 | -0.034686 |
| RPS25 | ribosomal protein S25 | -0.0346086 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0341939 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0334818 |
| NPR2 | natriuretic peptide receptor 2 | -0.0332322 |
| MATN3 | matrilin 3 | -0.0331687 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0326688 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.0326172 |
| CST3 | cystatin C | -0.0325885 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0322862 |
| RPS12 | ribosomal protein S12 | -0.0322433 |
| GNAS | GNAS complex locus | -0.0322233 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0320403 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0319074 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0314618 |
| APOE | apolipoprotein E | -0.0314266 |
| RPL27A | ribosomal protein L27a | -0.0308144 |
| RPL5 | ribosomal protein L5 | -0.0303189 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0299668 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0298621 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0296057 |
| RPS29 | ribosomal protein S29 | -0.0291136 |
| APOC1 | apolipoprotein C-I | -0.027751 |
| RPL30 | ribosomal protein L30 | -0.0275996 |
| IER3 | immediate early response 3 | -0.027397 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272409 |
| ENO1 | enolase 1, (alpha) | -0.0272346 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0271991 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0269463 |
| RPL36A | ribosomal protein L36a | -0.0269145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0268419 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0265641 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0264293 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0263932 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0260584 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0260091 |
| AHSG | alpha-2-HS-glycoprotein | -0.0259488 |
| RPL26 | ribosomal protein L26 | -0.025612 |
| DOK6 | docking protein 6 | -0.0254662 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0254399 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0253582 |
