| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cepharanthine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.186684 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.135139 |
| EZR | ezrin | 0.114428 |
| TMSB4X | thymosin beta 4, X-linked | 0.11199 |
| CAPRIN2 | caprin family member 2 | 0.0998715 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0824472 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0782286 |
| TXNRD1 | thioredoxin reductase 1 | 0.0656273 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0534047 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0482305 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0461783 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0452601 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0451532 |
| YBX3 | Y box binding protein 3 | 0.0433573 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0430613 |
| RTN4 | reticulon 4 | 0.0420723 |
| EMP1 | epithelial membrane protein 1 | 0.0420156 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0406552 |
| RUNX1 | runt-related transcription factor 1 | 0.0393356 |
| MT1X | metallothionein 1X | 0.0386561 |
| JUN | jun proto-oncogene | 0.0370797 |
| ANGPTL4 | angiopoietin-like 4 | 0.0363446 |
| CALR | calreticulin | 0.0362676 |
| RAI1 | retinoic acid induced 1 | 0.0350803 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0347101 |
| PLEC | plectin | 0.0340836 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0338996 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0337465 |
| FMNL2 | formin-like 2 | 0.0337427 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0337078 |
| TMEM41B | transmembrane protein 41B | 0.033551 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.033392 |
| SPAG9 | sperm associated antigen 9 | 0.0332665 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0328007 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0324782 |
| FOSL1 | FOS-like antigen 1 | 0.0321924 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0317397 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0314701 |
| CCNL1 | cyclin L1 | 0.03078 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.030701 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0305151 |
| CEP250 | centrosomal protein 250kDa | 0.0303774 |
| SDC4 | syndecan 4 | 0.0293942 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0288222 |
| PLAU | plasminogen activator, urokinase | 0.0287135 |
| AREG | amphiregulin | 0.0285683 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0281025 |
| DENND5A | DENN/MADD domain containing 5A | 0.028092 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0276966 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0272117 |
| RBM25 | RNA binding motif protein 25 | 0.027196 |
| TPR | translocated promoter region, nuclear basket protein | 0.0271445 |
| SYAP1 | synapse associated protein 1 | 0.0269257 |
| ERBIN | erbb2 interacting protein | 0.0269201 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0266455 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.02637 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0263543 |
| KLF6 | Kruppel-like factor 6 | 0.0261476 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0260266 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0259738 |
| OGA | O-GlcNAcase | 0.0257753 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0257098 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0250493 |
| FLNB | filamin B, beta | 0.0249665 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0249116 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0247767 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0245218 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.024435 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0243168 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0242288 |
| TPM3 | tropomyosin 3 | 0.0241551 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0237693 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0236724 |
| BRD4 | bromodomain containing 4 | 0.0234873 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0234403 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0234265 |
| RTTN | rotatin | 0.023344 |
| ADM | adrenomedullin | 0.0232029 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0231288 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0231222 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0230389 |
| SETD5 | SET domain containing 5 | 0.0223737 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0222605 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0222166 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.021949 |
| RNF213 | ring finger protein 213 | 0.0218305 |
| SEC24A | SEC24 family member A | 0.0217953 |
| DIAPH1 | diaphanous-related formin 1 | 0.0217708 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0217186 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0215425 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0213813 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0212116 |
| ACTG1 | actin gamma 1 | 0.0210125 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0208992 |
| CEP192 | centrosomal protein 192kDa | 0.0208817 |
| PHF21A | PHD finger protein 21A | 0.0208174 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0207036 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206654 |
| PTMA | prothymosin, alpha | 0.0206456 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0205073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205062 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.166903 |
| TP63 | tumor protein p63 | -0.14301 |
| CD44 | CD44 molecule (Indian blood group) | -0.135779 |
| VIM | vimentin | -0.116146 |
| EHBP1 | EH domain binding protein 1 | -0.0996312 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0991069 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0855469 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0829873 |
| CADM2 | cell adhesion molecule 2 | -0.0825627 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0801419 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0787937 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0714463 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0704196 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0674104 |
| EPHA4 | EPH receptor A4 | -0.0666793 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0661984 |
| EFNA5 | ephrin-A5 | -0.0661569 |
| TNS3 | tensin 3 | -0.063793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.063318 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0584569 |
| RPS8 | ribosomal protein S8 | -0.0575431 |
| EGFR | epidermal growth factor receptor | -0.0556812 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0545028 |
| DST | dystonin | -0.0537343 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0533855 |
| AEBP2 | AE binding protein 2 | -0.0476481 |
| RPS24 | ribosomal protein S24 | -0.0475524 |
| CANX | calnexin | -0.0433369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0426467 |
| RPS6 | ribosomal protein S6 | -0.0419838 |
| FTL | ferritin, light polypeptide | -0.0418719 |
| RPL31 | ribosomal protein L31 | -0.0418205 |
| NEK10 | NIMA-related kinase 10 | -0.0415017 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0410176 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0401051 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0397701 |
| RPL35A | ribosomal protein L35a | -0.0397299 |
| LDHA | lactate dehydrogenase A | -0.0393208 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0375256 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.037476 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0366201 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0364653 |
| PLSCR1 | phospholipid scramblase 1 | -0.0362655 |
| MYOF | myoferlin | -0.036173 |
| RIGI | RNA sensor RIG-I | -0.0351976 |
| RPS27A | ribosomal protein S27a | -0.0343821 |
| STK17A | serine/threonine kinase 17a | -0.0342644 |
| INTS6 | integrator complex subunit 6 | -0.034079 |
| RPS25 | ribosomal protein S25 | -0.0335544 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0334467 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330032 |
| TMEM123 | transmembrane protein 123 | -0.032934 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0327482 |
| RPL27A | ribosomal protein L27a | -0.0326756 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0325006 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0321812 |
| RPL34 | ribosomal protein L34 | -0.0320811 |
| RPL26 | ribosomal protein L26 | -0.0320039 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0317473 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0309639 |
| RACK1 | receptor for activated C kinase 1 | -0.0304391 |
| MAP4 | microtubule-associated protein 4 | -0.0304292 |
| RPS13 | ribosomal protein S13 | -0.0302051 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0291695 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291402 |
| RPS23 | ribosomal protein S23 | -0.029054 |
| HDAC9 | histone deacetylase 9 | -0.0285223 |
| RPL37 | ribosomal protein L37 | -0.0283319 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0277428 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0276642 |
| VCL | vinculin | -0.0275781 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.027575 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0275363 |
| DENND1A | DENN/MADD domain containing 1A | -0.0267363 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0265528 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0265488 |
| SP100 | SP100 nuclear antigen | -0.0264261 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0262863 |
| LRRC49 | leucine rich repeat containing 49 | -0.0262774 |
| RPS20 | ribosomal protein S20 | -0.0261853 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.026094 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0260859 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.02535 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0253422 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0253087 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0245595 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0245497 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0244975 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.02432 |
| OSMR | oncostatin M receptor | -0.0242279 |
| RPL9 | ribosomal protein L9 | -0.0241816 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0241067 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239239 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0237682 |
| HLA-E | major histocompatibility complex, class I, E | -0.0237402 |
| RPS28 | ribosomal protein S28 | -0.0236781 |
| DNER | delta/notch-like EGF repeat containing | -0.0234974 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.023474 |
| RPLP1 | ribosomal protein, large, P1 | -0.0234314 |
