| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cepharanthine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.325477 |
| EGFR | epidermal growth factor receptor | 0.142073 |
| MCL1 | myeloid cell leukemia 1 | 0.137729 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.128259 |
| CES1 | carboxylesterase 1 | 0.126632 |
| GRAMD1B | GRAM domain containing 1B | 0.126531 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.109627 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101505 |
| LAMA4 | laminin, alpha 4 | 0.100778 |
| SMAD3 | SMAD family member 3 | 0.0876524 |
| FAM13A | family with sequence similarity 13, member A | 0.081426 |
| LAMC2 | laminin, gamma 2 | 0.0781046 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0736629 |
| RNF213 | ring finger protein 213 | 0.0701331 |
| PLEC | plectin | 0.0682189 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0627875 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0618566 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0600475 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0573778 |
| SLTM | SAFB-like, transcription modulator | 0.0573519 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0569652 |
| ANXA2 | annexin A2 | 0.0525266 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0513519 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0512602 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0499981 |
| LAMB3 | laminin, beta 3 | 0.0488932 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0476479 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0473845 |
| CALR | calreticulin | 0.0456606 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0444197 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0429894 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.042691 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0420083 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0411811 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0410018 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0402063 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0393344 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0393059 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0387393 |
| AREG | amphiregulin | 0.0371891 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0367666 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0356156 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0355094 |
| MAGEA4 | melanoma antigen family A4 | 0.0340759 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0330994 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0329129 |
| MSN | moesin | 0.0325711 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0323493 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0322906 |
| BMP6 | bone morphogenetic protein 6 | 0.0310625 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0309226 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0308201 |
| EMP1 | epithelial membrane protein 1 | 0.0299023 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0293795 |
| CUL4A | cullin 4A | 0.0292592 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0284801 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.028082 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0280487 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0278628 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0278378 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0274984 |
| CD163L1 | CD163 molecule-like 1 | 0.027264 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.027203 |
| DSPP | dentin sialophosphoprotein | 0.0270292 |
| MT2A | metallothionein 2A | 0.0270024 |
| ATP11A | ATPase, class VI, type 11A | 0.0266858 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0260116 |
| PKM | pyruvate kinase, muscle | 0.0258566 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0257223 |
| CPE | carboxypeptidase E | 0.0253794 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0252435 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0252307 |
| LMO7 | LIM domain 7 | 0.0251744 |
| ACTN1 | actinin, alpha 1 | 0.0251171 |
| TMEM45B | transmembrane protein 45B | 0.0249658 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0248756 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0246849 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.024603 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.02414 |
| YBX3 | Y box binding protein 3 | 0.0238746 |
| FLNA | filamin A, alpha | 0.023804 |
| AHNAK | AHNAK nucleoprotein | 0.0234101 |
| APP | amyloid beta (A4) precursor protein | 0.0233436 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0232444 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0227904 |
| NDRG1 | N-myc downstream regulated 1 | 0.0218669 |
| ZNF638 | zinc finger protein 638 | 0.0218004 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0217432 |
| TPM3 | tropomyosin 3 | 0.0217365 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0217002 |
| C1D | C1D nuclear receptor corepressor | 0.0213359 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0213178 |
| MACROH2A1 | macroH2A.1 histone | 0.0211851 |
| KIAA1217 | KIAA1217 | 0.0207927 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0205962 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0205739 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0205605 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0205601 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0204749 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0200644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.158051 |
| TXNRD1 | thioredoxin reductase 1 | -0.091456 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0828504 |
| ASPH | aspartate beta-hydroxylase | -0.0781629 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0756321 |
| TMSB10 | thymosin beta 10 | -0.0636562 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0545907 |
| PATJ | PATJ crumbs cell polarity complex component | -0.046937 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0433581 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0408202 |
| RPL34 | ribosomal protein L34 | -0.0406518 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.039957 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0387125 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0383592 |
| S100A10 | S100 calcium binding protein A10 | -0.0369051 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0361345 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0350314 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0319975 |
| RPS24 | ribosomal protein S24 | -0.0319879 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0305326 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0300762 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299789 |
| CCND1 | cyclin D1 | -0.029341 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0288094 |
| RPS25 | ribosomal protein S25 | -0.0278537 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0269714 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0267607 |
| S100A6 | S100 calcium binding protein A6 | -0.0265913 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0259091 |
| NF1 | neurofibromin 1 | -0.0257244 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0252895 |
| RBM39 | RNA binding motif protein 39 | -0.0248219 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0240387 |
| TLK1 | tousled-like kinase 1 | -0.0237484 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0234167 |
| FBXO11 | F-box protein 11 | -0.0230994 |
| TMEM165 | transmembrane protein 165 | -0.0223706 |
| RPS2 | ribosomal protein S2 | -0.0223029 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0215362 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0213606 |
| RPLP0 | ribosomal protein, large, P0 | -0.0210875 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0205012 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0204725 |
| FTL | ferritin, light polypeptide | -0.0201358 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0199092 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0198252 |
| GPC6 | glypican 6 | -0.0197659 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0197103 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0196949 |
| WASF2 | WAS protein family, member 2 | -0.0196816 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0196787 |
| RPS6 | ribosomal protein S6 | -0.0194988 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.019465 |
| SBF2 | SET binding factor 2 | -0.0193175 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0191877 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0191678 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0190081 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0189624 |
| SUCO | SUN domain containing ossification factor | -0.018949 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0189215 |
| GNAS | GNAS complex locus | -0.0189058 |
| JMJD1C | jumonji domain containing 1C | -0.0188012 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0184606 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0183799 |
| RPS12 | ribosomal protein S12 | -0.0182948 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0182306 |
| RPL35A | ribosomal protein L35a | -0.0180041 |
| TPD52 | tumor protein D52 | -0.0178601 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0178147 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.017664 |
| SQSTM1 | sequestosome 1 | -0.017578 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0174326 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0174238 |
| USP34 | ubiquitin specific peptidase 34 | -0.0172467 |
| CANX | calnexin | -0.0172456 |
| ZNF217 | zinc finger protein 217 | -0.0172238 |
| USP53 | ubiquitin specific peptidase 53 | -0.0172198 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0171886 |
| CCNI | cyclin I | -0.0171314 |
| RIOK3 | RIO kinase 3 | -0.0171138 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0170633 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0170521 |
| NABP1 | nucleic acid binding protein 1 | -0.0169525 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0168878 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0168358 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0168251 |
| HMGA1 | high mobility group AT-hook 1 | -0.0168073 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0168048 |
| RPL7 | ribosomal protein L7 | -0.0167771 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0166971 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0166312 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0166027 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0164853 |
| RAB10 | RAB10, member RAS oncogene family | -0.0164686 |
| RPLP1 | ribosomal protein, large, P1 | -0.0164498 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0163666 |
| TNS3 | tensin 3 | -0.0161705 |
| IER3 | immediate early response 3 | -0.016033 |
| CD2AP | CD2-associated protein | -0.0158087 |
| SLMAP | sarcolemma associated protein | -0.0157922 |
