| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cepharanthine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.168207 |
| FN1 | fibronectin 1 | 0.145924 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.115107 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0973329 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0898432 |
| VEGFA | vascular endothelial growth factor A | 0.0813316 |
| NAV2 | neuron navigator 2 | 0.0751401 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0723235 |
| SMAD3 | SMAD family member 3 | 0.0722996 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0697488 |
| ADM | adrenomedullin | 0.0613486 |
| FAM20C | family with sequence similarity 20, member C | 0.0600208 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0580683 |
| LOXL2 | lysyl oxidase-like 2 | 0.0559586 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0539856 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0502313 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0500781 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0463634 |
| TMSB4X | thymosin beta 4, X-linked | 0.0462101 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0450333 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0441862 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0416578 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0398504 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0375154 |
| RNF213 | ring finger protein 213 | 0.0373326 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0371979 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370215 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0358604 |
| CEP250 | centrosomal protein 250kDa | 0.035646 |
| PFKP | phosphofructokinase, platelet | 0.0350614 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0349202 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0347572 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0331661 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0300386 |
| MLPH | melanophilin | 0.0296068 |
| PLEC | plectin | 0.0290989 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0288795 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0288226 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0288055 |
| SEPTIN9 | septin 9 | 0.0286252 |
| TNS1 | tensin 1 | 0.0275504 |
| ANGPTL4 | angiopoietin-like 4 | 0.0274018 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.027366 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0273402 |
| ZNF469 | zinc finger protein 469 | 0.0272438 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0272142 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0271259 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0265654 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0260346 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0259188 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0257123 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0255176 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0246577 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0245906 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0241618 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.023997 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0238322 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0234179 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0231377 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0228252 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0223736 |
| C1D | C1D nuclear receptor corepressor | 0.0223686 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0222517 |
| JUN | jun proto-oncogene | 0.0219778 |
| PKP1 | plakophilin 1 | 0.0219123 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0218397 |
| MMP2 | matrix metallopeptidase 2 | 0.0217102 |
| FAM13A | family with sequence similarity 13, member A | 0.0213139 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0210846 |
| TGFB1 | transforming growth factor, beta 1 | 0.0210174 |
| SVIL | supervillin | 0.0209693 |
| SFTPA2 | surfactant protein A2 | 0.0208141 |
| CA12 | carbonic anhydrase XII | 0.0208017 |
| RND3 | Rho family GTPase 3 | 0.0207552 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0207471 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | 0.02074 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0204297 |
| HLA-B | major histocompatibility complex, class I, B | 0.0202802 |
| PYGL | phosphorylase, glycogen, liver | 0.0201678 |
| SIK3 | SIK family kinase 3 | 0.0199872 |
| RNF144A | ring finger protein 144A | 0.0198734 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0193361 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0190118 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0189737 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0188949 |
| EZR | ezrin | 0.0188056 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0187164 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0184484 |
| TMOD1 | tropomodulin 1 | 0.0182924 |
| FLNA | filamin A, alpha | 0.0180097 |
| STRA6 | stimulated by retinoic acid 6 | 0.0179026 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0177565 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0175734 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0174409 |
| FAM219A | family with sequence similarity 219, member A | 0.0174307 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0173579 |
| NDRG1 | N-myc downstream regulated 1 | 0.0173325 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0171757 |
| STX1A | syntaxin 1A (brain) | 0.0171051 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0169763 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126506 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109256 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0927365 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0866833 |
| RBM39 | RNA binding motif protein 39 | -0.0780429 |
| USP34 | ubiquitin specific peptidase 34 | -0.0759601 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0740506 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0675934 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0664715 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0634049 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0620375 |
| VIM | vimentin | -0.0609178 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0598137 |
| GOLGA4 | golgin A4 | -0.059511 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0587962 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0577372 |
| PTMA | prothymosin, alpha | -0.0492858 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0487819 |
| CANX | calnexin | -0.0478533 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0464581 |
| NRG1 | neuregulin 1 | -0.0457115 |
| S100A6 | S100 calcium binding protein A6 | -0.04204 |
| GPC6 | glypican 6 | -0.0412737 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0412119 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0407138 |
| CD44 | CD44 molecule (Indian blood group) | -0.0402795 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0393968 |
| PCBP2 | poly(rC) binding protein 2 | -0.0393643 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0387973 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0374709 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0373437 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0370722 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0367976 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0367496 |
| NUMB | numb homolog (Drosophila) | -0.0367238 |
| TMSB10 | thymosin beta 10 | -0.0365718 |
| SBF2 | SET binding factor 2 | -0.0358102 |
| NF1 | neurofibromin 1 | -0.0353335 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0351554 |
| VMP1 | vacuole membrane protein 1 | -0.0350065 |
| JMJD1C | jumonji domain containing 1C | -0.0348496 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0346973 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343584 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0343079 |
| RIOK3 | RIO kinase 3 | -0.0340843 |
| RPL34 | ribosomal protein L34 | -0.0338967 |
| PARD3 | par-3 family cell polarity regulator | -0.0337304 |
| ZNF292 | zinc finger protein 292 | -0.0333208 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.033158 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0329172 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0328991 |
| VRK2 | vaccinia related kinase 2 | -0.0328127 |
| TMEM263 | transmembrane protein 263 | -0.0327583 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0322466 |
| STC1 | stanniocalcin 1 | -0.0320995 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0318765 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0316634 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.031314 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0312404 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0310883 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0310455 |
| RPS24 | ribosomal protein S24 | -0.0308996 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0305274 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0302005 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0298154 |
| EHBP1 | EH domain binding protein 1 | -0.029493 |
| VCL | vinculin | -0.029363 |
| PRRC2C | proline-rich coiled-coil 2C | -0.029311 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0292635 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0291826 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0290651 |
| ENO1 | enolase 1, (alpha) | -0.0281413 |
| COG5 | component of oligomeric golgi complex 5 | -0.0280576 |
| DIAPH2 | diaphanous-related formin 2 | -0.0279042 |
| RPS2 | ribosomal protein S2 | -0.0279028 |
| RPS21 | ribosomal protein S21 | -0.0277581 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0277249 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275225 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0273115 |
| SP100 | SP100 nuclear antigen | -0.0273101 |
| EXOC4 | exocyst complex component 4 | -0.0270215 |
| ZNF609 | zinc finger protein 609 | -0.0270154 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0269667 |
| IL6ST | interleukin 6 signal transducer | -0.0268976 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0264885 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0263866 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0263648 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0263376 |
| DST | dystonin | -0.0262514 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0261999 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0260148 |
| RPLP0 | ribosomal protein, large, P0 | -0.0257639 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0257091 |
| SLC38A1 | solute carrier family 38, member 1 | -0.025673 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0255592 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0254421 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0253985 |
| FTL | ferritin, light polypeptide | -0.0253489 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0250489 |
| KYNU | kynureninase | -0.0250023 |
