| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cepharanthine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.363353 |
| GRAMD1B | GRAM domain containing 1B | 0.153266 |
| MT2A | metallothionein 2A | 0.143957 |
| ACTG1 | actin gamma 1 | 0.10602 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.100233 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0962322 |
| MCL1 | myeloid cell leukemia 1 | 0.0916735 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0781687 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0690058 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0616782 |
| BRD2 | bromodomain containing 2 | 0.0565225 |
| CALR | calreticulin | 0.0548424 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.053942 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0523668 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0504282 |
| FAM107B | family with sequence similarity 107, member B | 0.0499545 |
| FLNA | filamin A, alpha | 0.0493575 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0491274 |
| HLA-B | major histocompatibility complex, class I, B | 0.0480287 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0471482 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0469056 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0459202 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0456936 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.044455 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.043627 |
| USP36 | ubiquitin specific peptidase 36 | 0.0405748 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0403181 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0387763 |
| TPM3 | tropomyosin 3 | 0.0383268 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0379214 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0376346 |
| RPL3 | ribosomal protein L3 | 0.03756 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0363063 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0357508 |
| FLNB | filamin B, beta | 0.0354184 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0347047 |
| EGR1 | early growth response 1 | 0.0334014 |
| CCNL1 | cyclin L1 | 0.0333344 |
| COPA | coatomer protein complex, subunit alpha | 0.0332748 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0329221 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0324537 |
| PLEC | plectin | 0.0319516 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0318271 |
| APP | amyloid beta (A4) precursor protein | 0.0315919 |
| LAMA5 | laminin, alpha 5 | 0.0315898 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0308597 |
| ADM | adrenomedullin | 0.0307745 |
| HLA-A | major histocompatibility complex, class I, A | 0.0307289 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0305522 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0301618 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0299992 |
| IL6 | interleukin 6 | 0.0299947 |
| FMNL2 | formin-like 2 | 0.0298713 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0294811 |
| JUN | jun proto-oncogene | 0.0292293 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292077 |
| SMAD3 | SMAD family member 3 | 0.0284191 |
| WWOX | WW domain containing oxidoreductase | 0.0282936 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0280317 |
| HLA-C | major histocompatibility complex, class I, C | 0.0279325 |
| CMIP | c-Maf inducing protein | 0.027757 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0271089 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0269853 |
| RBM25 | RNA binding motif protein 25 | 0.0268567 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0267465 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0266712 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0263096 |
| ATP11A | ATPase, class VI, type 11A | 0.026232 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0257414 |
| PRRC2C | proline-rich coiled-coil 2C | 0.025649 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0252228 |
| LAMC2 | laminin, gamma 2 | 0.0250702 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.02504 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0249334 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0248963 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0248377 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0244513 |
| AATF | apoptosis antagonizing transcription factor | 0.0243903 |
| NDRG1 | N-myc downstream regulated 1 | 0.0243814 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0239681 |
| SVIL | supervillin | 0.0239631 |
| ANGPTL4 | angiopoietin-like 4 | 0.0236791 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0234177 |
| CCNY | cyclin Y | 0.0232803 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0232488 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0231572 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0230992 |
| CTBP2 | C-terminal binding protein 2 | 0.0230052 |
| PDE8A | phosphodiesterase 8A | 0.0229897 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0229737 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0229664 |
| CABIN1 | calcineurin binding protein 1 | 0.0228718 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.022793 |
| MSN | moesin | 0.022787 |
| ACTN1 | actinin, alpha 1 | 0.022717 |
| RCOR1 | REST corepressor 1 | 0.0226237 |
| RPL7A | ribosomal protein L7a | 0.022542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225386 |
| SQSTM1 | sequestosome 1 | 0.0225003 |
| ITGB5 | integrin, beta 5 | 0.022456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.198477 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174303 |
| FTL | ferritin, light polypeptide | -0.172961 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.145335 |
| VIM | vimentin | -0.134621 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0913244 |
| S100A6 | S100 calcium binding protein A6 | -0.0664724 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.063626 |
| TMSB10 | thymosin beta 10 | -0.0584794 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0541668 |
| S100A10 | S100 calcium binding protein A10 | -0.0513011 |
| RPL19 | ribosomal protein L19 | -0.0506976 |
| RPLP0 | ribosomal protein, large, P0 | -0.0503707 |
| PFN1 | profilin 1 | -0.0499583 |
| PTMA | prothymosin, alpha | -0.0494874 |
| RPS21 | ribosomal protein S21 | -0.04661 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0446756 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0442257 |
| RPS25 | ribosomal protein S25 | -0.0435436 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0433409 |
| RPLP1 | ribosomal protein, large, P1 | -0.0432461 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.042314 |
| RPL34 | ribosomal protein L34 | -0.0419577 |
| STC1 | stanniocalcin 1 | -0.0417594 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0411008 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0395101 |
| TMEM123 | transmembrane protein 123 | -0.03871 |
| TXNRD1 | thioredoxin reductase 1 | -0.0385761 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0384429 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.038267 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0369723 |
| RPS24 | ribosomal protein S24 | -0.0367302 |
| RPS5 | ribosomal protein S5 | -0.0360432 |
| SRGN | serglycin | -0.0358213 |
| NEGR1 | neuronal growth regulator 1 | -0.0346036 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0344752 |
| PYGL | phosphorylase, glycogen, liver | -0.0339284 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336802 |
| CANX | calnexin | -0.0325777 |
| DST | dystonin | -0.0323271 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0321249 |
| AHR | aryl hydrocarbon receptor | -0.0320622 |
| HMGB1 | high mobility group box 1 | -0.0315637 |
| RPS8 | ribosomal protein S8 | -0.0307979 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0307506 |
| LDHA | lactate dehydrogenase A | -0.0299718 |
| DENND4A | DENN/MADD domain containing 4A | -0.0295379 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0292379 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0289789 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0288807 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0288465 |
| USP3 | ubiquitin specific peptidase 3 | -0.0282897 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0279948 |
| BICC1 | BicC family RNA binding protein 1 | -0.0279285 |
| EFNA5 | ephrin-A5 | -0.0275388 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0274346 |
| RPL30 | ribosomal protein L30 | -0.0273681 |
| RHOA | ras homolog family member A | -0.0270435 |
| RPL7 | ribosomal protein L7 | -0.02679 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0267759 |
| S100A9 | S100 calcium binding protein A9 | -0.0267329 |
| RPS23 | ribosomal protein S23 | -0.0265032 |
| DEK | DEK proto-oncogene | -0.0262479 |
| RPL8 | ribosomal protein L8 | -0.0261914 |
| TAGLN2 | transgelin 2 | -0.0260554 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258594 |
| EHBP1 | EH domain binding protein 1 | -0.0258343 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0255947 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0254651 |
| TKT | transketolase | -0.0251714 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0251517 |
| ENO1 | enolase 1, (alpha) | -0.0248186 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0246723 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0242891 |
| RPS20 | ribosomal protein S20 | -0.024243 |
| TUBA1B | tubulin, alpha 1b | -0.0241291 |
| RPS15 | ribosomal protein S15 | -0.0238958 |
| CHN1 | chimerin 1 | -0.0238164 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0237766 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0237194 |
| RPS16 | ribosomal protein S16 | -0.0237026 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0234667 |
| RPL23 | ribosomal protein L23 | -0.0234016 |
| AHNAK | AHNAK nucleoprotein | -0.0233655 |
| SERF2 | small EDRK-rich factor 2 | -0.0232944 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0232703 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0228337 |
| RPS6 | ribosomal protein S6 | -0.0227257 |
| RPL23A | ribosomal protein L23a | -0.0225506 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.022535 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0222193 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0218851 |
| GOLT1B | golgi transport 1B | -0.021758 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0217358 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.021631 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0215784 |
| AK1 | adenylate kinase 1 | -0.0215068 |
| SEPTIN7 | septin 7 | -0.021354 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0213016 |
| RPL11 | ribosomal protein L11 | -0.0211971 |
