| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cepharanthine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.184849 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.175169 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.144258 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.142375 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.130425 |
| SVIL | supervillin | 0.129477 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.118333 |
| RIGI | RNA sensor RIG-I | 0.114712 |
| TXNRD1 | thioredoxin reductase 1 | 0.0981294 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.09757 |
| LMO7 | LIM domain 7 | 0.0968333 |
| MYO5B | myosin VB | 0.0956431 |
| KYNU | kynureninase | 0.0909787 |
| KRT17 | keratin 17, type I | 0.0885986 |
| ATP11A | ATPase, class VI, type 11A | 0.0882012 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0878796 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0861056 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0845207 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0842733 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0833543 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0747935 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.07351 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0716436 |
| ANXA2 | annexin A2 | 0.0713421 |
| INTS1 | integrator complex subunit 1 | 0.0712628 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0691397 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0656693 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0625121 |
| NDRG1 | N-myc downstream regulated 1 | 0.0593453 |
| TJP1 | tight junction protein 1 | 0.0589272 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0581889 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0571137 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.056094 |
| CALR | calreticulin | 0.055351 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0552299 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0542305 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0533948 |
| RBM5 | RNA binding motif protein 5 | 0.0529613 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0525395 |
| FA2H | fatty acid 2-hydroxylase | 0.0521259 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0510248 |
| TUFT1 | tuftelin 1 | 0.0509574 |
| TSC22D2 | TSC22 domain family, member 2 | 0.049534 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0490692 |
| RNF213 | ring finger protein 213 | 0.048298 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0480084 |
| TOP1 | topoisomerase (DNA) I | 0.0466074 |
| RNF149 | ring finger protein 149 | 0.0461501 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0457692 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0454808 |
| EGFR | epidermal growth factor receptor | 0.0454143 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0452866 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0447909 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0447496 |
| DSG2 | desmoglein 2 | 0.044224 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.044182 |
| FOXO3 | forkhead box O3 | 0.0437149 |
| PFKP | phosphofructokinase, platelet | 0.0436141 |
| ABLIM1 | actin binding LIM protein 1 | 0.043417 |
| DUSP4 | dual specificity phosphatase 4 | 0.0433715 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0433555 |
| KRT8 | keratin 8, type II | 0.0419985 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0418426 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0415 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0393417 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0386398 |
| SECISBP2L | SECIS binding protein 2-like | 0.0381368 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0377182 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0376411 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0374495 |
| NPTN | neuroplastin | 0.0373715 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0372042 |
| DUSP10 | dual specificity phosphatase 10 | 0.0368532 |
| RHOA | ras homolog family member A | 0.0367334 |
| VCL | vinculin | 0.0360222 |
| ABHD17C | abhydrolase domain containing 17C | 0.0357327 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0355082 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0353448 |
| GLG1 | golgi glycoprotein 1 | 0.0351655 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0348263 |
| JUP | junction plakoglobin | 0.0347539 |
| TMSB10 | thymosin beta 10 | 0.0344148 |
| RREB1 | ras responsive element binding protein 1 | 0.0343755 |
| ADM | adrenomedullin | 0.0342216 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0337826 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0332591 |
| C3 | complement component 3 | 0.033146 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0330737 |
| MYO5C | myosin VC | 0.0327598 |
| MUC16 | mucin 16, cell surface associated | 0.0327228 |
| SIK3 | SIK family kinase 3 | 0.0326961 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0326136 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0325462 |
| TCF12 | transcription factor 12 | 0.032508 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0324726 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0323839 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0320871 |
| SDC4 | syndecan 4 | 0.0319707 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0318838 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.031727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10906 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0967008 |
| FN1 | fibronectin 1 | -0.0904915 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0892186 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0851368 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0843871 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0832875 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0823346 |
| ASPH | aspartate beta-hydroxylase | -0.0823004 |
| PRKCA | protein kinase C, alpha | -0.0764835 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0753951 |
| PTK2 | protein tyrosine kinase 2 | -0.0701177 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0698668 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0672688 |
| RORA | RAR-related orphan receptor A | -0.0648649 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0648176 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.063302 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0632255 |
| SBF2 | SET binding factor 2 | -0.0629646 |
| NF1 | neurofibromin 1 | -0.0620629 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0618396 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0618061 |
| GPC6 | glypican 6 | -0.0601371 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0567294 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0566992 |
| PTMA | prothymosin, alpha | -0.0559415 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.05471 |
| DST | dystonin | -0.0543756 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0539446 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0538766 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0534249 |
| MED13L | mediator complex subunit 13-like | -0.0527346 |
| VIM | vimentin | -0.0516865 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0513351 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0507007 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0504172 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0486677 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0484832 |
| GOLGA4 | golgin A4 | -0.0463868 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0462193 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0460432 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0453564 |
| DENND4A | DENN/MADD domain containing 4A | -0.0447867 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0446745 |
| INTS6 | integrator complex subunit 6 | -0.0445291 |
| CD2AP | CD2-associated protein | -0.044343 |
| RBM47 | RNA binding motif protein 47 | -0.0441017 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0431588 |
| MYO10 | myosin X | -0.0430591 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0430039 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0428965 |
| SETD5 | SET domain containing 5 | -0.0428499 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0422398 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0420304 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0410717 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0407987 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0407145 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0403607 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0403436 |
| MCL1 | myeloid cell leukemia 1 | -0.0402559 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0402462 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0396152 |
| XPO1 | exportin 1 | -0.0394189 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0393747 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0390202 |
| RASA2 | RAS p21 protein activator 2 | -0.0385329 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0384259 |
| ATP13A3 | ATPase type 13A3 | -0.0384084 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0383114 |
| PARD3 | par-3 family cell polarity regulator | -0.0381585 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0379713 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0379698 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0375248 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0373325 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0373041 |
| TAOK3 | TAO kinase 3 | -0.0365331 |
| PGK1 | phosphoglycerate kinase 1 | -0.0362171 |
| GLIS3 | GLIS family zinc finger 3 | -0.0360237 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0358914 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0357593 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0357239 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0356976 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0356359 |
| FRMD5 | FERM domain containing 5 | -0.0356154 |
| MYO1E | myosin IE | -0.035222 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0348845 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0341396 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0339132 |
| DENND1A | DENN/MADD domain containing 1A | -0.0337867 |
| TMEM87A | transmembrane protein 87A | -0.0336087 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033354 |
| MAP4 | microtubule-associated protein 4 | -0.0332026 |
| PMM2 | phosphomannomutase 2 | -0.0331374 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.03306 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0330418 |
| GSK3B | glycogen synthase kinase 3 beta | -0.032778 |
| FTL | ferritin, light polypeptide | -0.0322334 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0319673 |
| ATOSA | atos homolog A | -0.031866 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0316553 |
