| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cepharanthine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cepharanthine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.209848 |
| FN1 | fibronectin 1 | 0.153327 |
| ACTG1 | actin gamma 1 | 0.142206 |
| NDRG1 | N-myc downstream regulated 1 | 0.122496 |
| PLEC | plectin | 0.111669 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111389 |
| VEGFA | vascular endothelial growth factor A | 0.0994629 |
| CALR | calreticulin | 0.0946186 |
| TMSB4X | thymosin beta 4, X-linked | 0.0885534 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0858708 |
| SDC4 | syndecan 4 | 0.0793542 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0624813 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0624392 |
| HLA-B | major histocompatibility complex, class I, B | 0.0619172 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0602269 |
| LAMB3 | laminin, beta 3 | 0.058283 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0560705 |
| ADM | adrenomedullin | 0.0537319 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0530857 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0530453 |
| CTSB | cathepsin B | 0.0525775 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0520447 |
| LAMC2 | laminin, gamma 2 | 0.0490103 |
| MSN | moesin | 0.0443521 |
| TPM3 | tropomyosin 3 | 0.0438496 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0433167 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0426243 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0412642 |
| G0S2 | G0/G1 switch 2 | 0.0404243 |
| RBM25 | RNA binding motif protein 25 | 0.0377185 |
| TJP2 | tight junction protein 2 | 0.0376283 |
| CCNL1 | cyclin L1 | 0.0375902 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0373499 |
| FLNA | filamin A, alpha | 0.0361401 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0359964 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0353792 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0352596 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0349806 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0345637 |
| APP | amyloid beta (A4) precursor protein | 0.034533 |
| SMAD3 | SMAD family member 3 | 0.0342872 |
| NECTIN4 | nectin cell adhesion molecule 4 | 0.034133 |
| MT2A | metallothionein 2A | 0.0341059 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0338947 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.032747 |
| TXNIP | thioredoxin interacting protein | 0.032249 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0314995 |
| EZR | ezrin | 0.0313122 |
| DUSP10 | dual specificity phosphatase 10 | 0.0312308 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0311852 |
| MYO5B | myosin VB | 0.0311847 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0302678 |
| CLDN4 | claudin 4 | 0.0292581 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0288172 |
| HLA-A | major histocompatibility complex, class I, A | 0.0287776 |
| MYO10 | myosin X | 0.0283814 |
| DSPP | dentin sialophosphoprotein | 0.0283237 |
| BRD2 | bromodomain containing 2 | 0.0264975 |
| MCL1 | myeloid cell leukemia 1 | 0.026378 |
| RPL3 | ribosomal protein L3 | 0.0261658 |
| GPX4 | glutathione peroxidase 4 | 0.0259685 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0257733 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0257593 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0256648 |
| RNF213 | ring finger protein 213 | 0.0252825 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0249472 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0247656 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.02447 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0238966 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0238646 |
| BCL2L1 | BCL2-like 1 | 0.0238146 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0237319 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0235546 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0234781 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0231758 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0229068 |
| DUSP5 | dual specificity phosphatase 5 | 0.0225597 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0223846 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0221871 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.022119 |
| PLAU | plasminogen activator, urokinase | 0.0220694 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0218601 |
| NOTCH2 | notch 2 | 0.0218138 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0216767 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0215495 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.021518 |
| RPN1 | ribophorin I | 0.0214765 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0213405 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0202012 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0201976 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0201881 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0200444 |
| RPL7A | ribosomal protein L7a | 0.0200049 |
| JUP | junction plakoglobin | 0.0198914 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0198285 |
| UPP1 | uridine phosphorylase 1 | 0.0197427 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0197303 |
| SEPTIN9 | septin 9 | 0.0196946 |
| MKRN1 | makorin ring finger protein 1 | 0.0195602 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0194755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.262908 |
| S100A6 | S100 calcium binding protein A6 | -0.0993061 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0990367 |
| RPL34 | ribosomal protein L34 | -0.08758 |
| HMGA1 | high mobility group AT-hook 1 | -0.074438 |
| ASPH | aspartate beta-hydroxylase | -0.0679277 |
| RPLP0 | ribosomal protein, large, P0 | -0.066973 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0644556 |
| CANX | calnexin | -0.0637993 |
| RPLP1 | ribosomal protein, large, P1 | -0.0612933 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0594586 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0590574 |
| RACK1 | receptor for activated C kinase 1 | -0.0569336 |
| S100A10 | S100 calcium binding protein A10 | -0.0552546 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0535106 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0526485 |
| RPS24 | ribosomal protein S24 | -0.0496193 |
| RPS8 | ribosomal protein S8 | -0.0495514 |
| CCND1 | cyclin D1 | -0.0494814 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0475807 |
| SQSTM1 | sequestosome 1 | -0.0474676 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0467904 |
| RPS6 | ribosomal protein S6 | -0.0465019 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0456113 |
| ENO1 | enolase 1, (alpha) | -0.0448405 |
| RPL30 | ribosomal protein L30 | -0.0445653 |
| RPS23 | ribosomal protein S23 | -0.0440719 |
| TMSB10 | thymosin beta 10 | -0.0434317 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0429301 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0424515 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0423111 |
| CD2AP | CD2-associated protein | -0.0422269 |
| RPL35A | ribosomal protein L35a | -0.0420899 |
| GOLGA4 | golgin A4 | -0.0415026 |
| RPL27A | ribosomal protein L27a | -0.0395352 |
| RPS13 | ribosomal protein S13 | -0.0393998 |
| ARF1 | ADP-ribosylation factor 1 | -0.0389047 |
| VIM | vimentin | -0.0380705 |
| TMEM123 | transmembrane protein 123 | -0.037758 |
| VCL | vinculin | -0.0376362 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0374759 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0356706 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0356647 |
| RPL32 | ribosomal protein L32 | -0.0350683 |
| TPM4 | tropomyosin 4 | -0.0338915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0338232 |
| GNAS | GNAS complex locus | -0.0336472 |
| FBXO32 | F-box protein 32 | -0.0335932 |
| LDHA | lactate dehydrogenase A | -0.0335751 |
| TKT | transketolase | -0.0332165 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0323941 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0319701 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0318005 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0317238 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0316984 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0315232 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0314309 |
| CERT1 | ceramide transporter 1 | -0.0307071 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0304258 |
| MAP4 | microtubule-associated protein 4 | -0.0304122 |
| RPL11 | ribosomal protein L11 | -0.0296755 |
| TMEM263 | transmembrane protein 263 | -0.0294039 |
| KRT7 | keratin 7, type II | -0.0287926 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0287536 |
| RPS25 | ribosomal protein S25 | -0.028678 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0285182 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0284223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283107 |
| RPL7 | ribosomal protein L7 | -0.0280597 |
| CEP350 | centrosomal protein 350kDa | -0.0275324 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0274043 |
| RPS27A | ribosomal protein S27a | -0.0273987 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0266406 |
| ZNF292 | zinc finger protein 292 | -0.026469 |
| EPCAM | epithelial cell adhesion molecule | -0.0264224 |
| RPS16 | ribosomal protein S16 | -0.0263598 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0260093 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0259589 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0259504 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0259368 |
| TFG | TRK-fused gene | -0.0259281 |
| FBXO34 | F-box protein 34 | -0.0253664 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0248877 |
| JMJD1C | jumonji domain containing 1C | -0.0248028 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0247516 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0246829 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0244357 |
| NPC2 | Niemann-Pick disease, type C2 | -0.024368 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0240981 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0240747 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0240692 |
| RPL37 | ribosomal protein L37 | -0.0240328 |
| RAB1A | RAB1A, member RAS oncogene family | -0.023984 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0237085 |
| NF1 | neurofibromin 1 | -0.0233983 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0233158 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0233014 |
| FAM162A | family with sequence similarity 162, member A | -0.0232886 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.023226 |
| RTN3 | reticulon 3 | -0.0230591 |
